Electrically enhanced retrieval of material from vessel lumens

Patent metadata

Field	Value
Publication number	US-2022125455-A1
Application number	US-202217647319-A
Country	US
Kind code	A1
Filing date	Jan 6, 2022
Priority date	Dec 11, 2017
Publication date	Apr 28, 2022
Grant date	—

Abstract

Retrieval of material from vessel lumens can be improved by electrically enhancing attachment of the material to the removal device. The removal device can have a core assembly that includes a hypotube coupled to a first electrical terminal and a pushwire coupled to a second electrical terminal, the pushwire extending through the hypotube lumen. An insulating layer separates the hypotube and the pushwire, and an interventional element is coupled to a distal end of the pushwire. The interventional element can be disposed adjacent to a thrombus. An electrical signal is delivered to the interventional element to promote adhesion of the thrombus to the interventional element. The electrical signal can optionally be a periodic waveform, and the total energy delivered can be between 0.75-24,000 mJ and the peak current delivered via the electrical signal can be between 0.5-5 mA.

First claim

1 . (canceled)

2 . A system for removing a thrombus, the system comprising:
a delivery electrode comprising an interventional element configured to be disposed proximate to or adjacent to a thrombus within a blood vessel, the interventional element comprising a self-expandable mesh; a pushwire having a distal end portion coupled to the interventional element; a return electrode; and a current generator having a first terminal in electrical communication with the delivery electrode and a second terminal electrically coupled to the return electrode, the current generator configured to deliver an electrical signal to the interventional element for a predetermined time period, wherein the peak current delivered via the electrical signal is between 0.5-5 mA, and wherein the predetermined time period is no more than 5 minutes.

3 . The system of claim 2 , wherein the current generator comprises a power source and a processor coupled to a memory, the memory storing the instructions for causing the power source to deliver the electrical signal to the interventional element.

4 . The system of claim 2 , wherein the current generator comprises a power source and drive circuitry configured to deliver the electrical signal to the interventional element.

5 . The system of claim 2 , wherein the predetermined time period is no more than 2 minutes.

6 . The system of claim 2 , wherein the total energy delivered via the electrical signal over the predetermined time period is between 120-24,000 mJ.

7 . The system of claim 2 , wherein the total energy delivered via the electrical signal over the predetermined time period is between 120-5000 mJ.

8 . The system of claim 2 , wherein the total charge delivered via the electrical signal over the predetermined time period is between 30-1200 mC.

9 . The system of claim 2 , wherein the total charge delivered via the electrical signal over the predetermined time period is between 120-160 mC.

10 . The system of claim 2 , wherein the electrical signal comprises a square waveform.

11 . The system of claim 2 , wherein the interventional element comprises an electrically conductive self-expandable device.

12 . The system of claim 2 , wherein the interventional element comprises a stent retriever.

13 . The system of claim 2 , wherein the interventional element comprises a thrombectomy device.

14 . The system of claim 2 , wherein the interventional element comprises a removal device.

15 . The system of claim 2 , wherein the electrical signal comprises a periodic waveform or a constant direct current.

16 . A system for removing a thrombus, the system comprising:
a first electrode comprising an interventional element, the interventional element comprising a self-expandable mesh; a core member having a distal end portion coupled to the interventional element; a second electrode; and a current generator having a first terminal in electrical communication with the first electrode and a second terminal electrically coupled to the second electrode, the current generator configured to deliver an electrical signal to the interventional element for a predetermined time period, wherein the peak current delivered via the electrical signal is between 0.5-5 mA, and wherein the predetermined time period is no more than 5 minutes.

17 . The system of claim 16 , wherein the electrical signal comprises a monopolar square wave.

18 . The system of claim 16 , wherein the interventional element comprises a tubular thrombectomy device.

19 . The system of claim 16 , wherein the predetermined time period is no more than 2 minutes.

20 . The system of claim 16 , wherein the total energy delivered via the electrical signal over the predetermined time period is between 120-5000 mJ.

21 . The system of claim 16 , wherein the total charge delivered via the electrical signal over the predetermined time period is between 120-160 mC.

Assignees

• Covidien Lp

Inventors

• Girdhar Gaurav
• Nguyen Hoai
• Huynh Andy
• Nageswaran Ashok
• Andrews Christopher

Classifications

• A61B2018/00601

  Cutting · CPC title

• A61B2018/00273

  Anchoring means for temporary attachment of a device to tissue · CPC title

• A61B2017/00867

  shape memory effect · CPC title

• A61B2017/22034

  for gripping the obstruction or the tissue part from inside · CPC title

• A61B2017/00929

  isolating electrical current · CPC title