Bio-based N-acetyl-L-methionine and use thereof
US-10750762-B2 · Aug 25, 2020 · US
Methods for preparing n-acetyl-l-methionine
US2022042000A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2022042000-A1 |
| Application number | US-202117452565-A |
| Country | US |
| Kind code | A1 |
| Filing date | Oct 27, 2021 |
| Priority date | Jul 20, 2016 |
| Publication date | Feb 10, 2022 |
| Grant date | — |
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Abstract
Official abstract text for this publication.
The present disclosure relates to a polypeptide having an acyltransferase activity or a microorganism including the same; a composition for preparing N-acetyl-L-methionine, the composition including the polypeptide or microorganism; and a method of preparing N-acetyl-L-methionine using the polypeptide or microorganism. Further, the present disclosure relates to a polynucleotide encoding the polypeptide and an expression vector including the polynucleotide. Since the microorganism including a novel acyltransferase according to the present disclosure has enhanced acyltransferase activity, this microorganism can be efficiently used for producing N-acetyl-L-methionine by acetylating L-methionine.
First claim
Opening claim text (preview).
1 - 8 . (canceled) 9 . The method according to claim 10 , further comprising: recovering N-acetyl-L-methionine, which is the acetylated L-methionine. 10 . A method of preparing N-acetyl-L-methionine, comprising: acetylating L-methionine using (i) a polypeptide having an acyltransferase activity and having the amino acid sequence of any one of SEQ ID NOS. 1 to 3 or the amino acid sequence having 90% or more homology to one of such amino acid sequences; (ii) a microorganism producing N-acetyl-L-methionine from L-methionine, the microorganism comprising the polypeptide or a culture of the microorganism; or (iii) a combination of (i) and (ii). 11 . The method according to claim 10 , wherein the microorganism is selected from the group consisting of Escherichia sp., Corynebacterium sp., Saccharomyces sp., and Yarrowia sp. 12 . The method according to claim 9 , wherein the microorganism is selected from the group consisting of Escherichia sp., Corynebacterium sp., Saccharomyces sp., and Yarrowia sp.
Assignees
Inventors
Classifications
Corynebacterium · CPC title
Bacillus subtilis {; Hay bacillus; Grass bacillus} · CPC title
transferring groups other than amino-acyl groups (2.3.1) · CPC title
Pseudomonas putida · CPC title
- C12P13/12Primary
Methionine; Cysteine; Cystine · CPC title
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- What does patent US2022042000A1 cover?
- The present disclosure relates to a polypeptide having an acyltransferase activity or a microorganism including the same; a composition for preparing N-acetyl-L-methionine, the composition including the polypeptide or microorganism; and a method of preparing N-acetyl-L-methionine using the polypeptide or microorganism. Further, the present disclosure relates to a polynucleotide encoding the pol…
- Who is the assignee on this patent?
- Cj Cheiljedang Corp
- What technology area does this patent fall under?
- Primary CPC classification C12P13/12. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Thu Feb 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).