Apparatus and method for treatment of post thrombotic syndrome

Patent metadata

Field	Value
Publication number	US-2022015784-A1
Application number	US-202016928678-A
Country	US
Kind code	A1
Filing date	Jul 14, 2020
Priority date	Jul 14, 2020
Publication date	Jan 20, 2022
Grant date	—

Abstract

A medical apparatus has a thrombectomy device disposed in a sheath lumen of a sheath that is movable between an initial extended position and a retracted position. The thrombectomy device includes a first elongate cannula having a distal tip, a guidewire lumen, and a perforated region, which is proximal to the distal tip and is in fluid communication with the guidewire lumen. A second elongate cannula, which is configured to rotate, has a second lumen and a mechanical thrombectomy whisk, which is proximal to the distal tip. A third elongate cannula has a third exterior surface, a third lumen, an inflation passageway, an inflatable balloon connected to the third exterior surface, and an expandable embolic filter connected to the third exterior surface at a location distal to the inflatable balloon. The first elongate cannula is disposed in the second lumen. The second elongate cannula is disposed in the third lumen.

First claim

What is claimed is:

1 . A medical apparatus, comprising:
a sheath having a sheath distal end and a sheath lumen, the sheath movable between an initial extended sheath position and a retracted sheath position; and a thrombectomy device, the thrombectomy device disposed in the sheath lumen, the thrombectomy device including:
a first elongate cannula having a proximal end, a distal end having a distal tip, a guidewire lumen, and a perforated region, the perforated region having a plurality of perforations in fluid communication with the guidewire lumen, the perforated region proximal to the distal tip;
a second elongate cannula having a second proximal end, a second distal end, a second lumen, and a mechanical thrombectomy whisk, the first elongate cannula disposed in the second lumen, the mechanical thrombectomy whisk proximal to the distal tip, the second elongate cannula configured to rotate;
a third elongate cannula having a third exterior surface, a third proximal end, a third distal end, a third lumen, and an expandable embolic filter connected to the third exterior surface, the second elongate cannula disposed in the third lumen; and
a fourth elongate cannula having a fourth exterior surface, a fourth proximal end, a fourth distal end, a fourth lumen, an inflation passageway, and an inflatable balloon connected to the fourth exterior surface, the third elongate cannula disposed in the fourth lumen, the inflatable balloon in fluid communication with the inflation passageway.

2 . The medical apparatus of claim 1 , wherein in the retracted sheath position, the sheath distal end is entirely proximal to the inflatable balloon.

3 . The medical apparatus of claim 1 , wherein the second elongate cannula is configured to move from an initial second elongate extended position to a plurality of second elongate cannula retracted positions, in at least one of the plurality of second elongate retracted positions the mechanical thrombectomy whisk is proximally adjacent to the perforated region.

4 . The medical apparatus of claim 1 , wherein the second elongate cannula is configured to move from an initial second elongate cannula retracted position to a plurality of second elongate cannula extended positions, the second elongate cannula is configured to move to at least one of the plurality of second elongate cannula extended positions to position the mechanical thrombectomy whisk in alignment with a thrombus in a vessel.

5 . The medical apparatus of claim 4 , wherein the plurality of second elongate cannula extended positions includes a distal-most second elongate cannula extended position, the mechanical thrombectomy whisk is aligned with the perforated region when the second elongate cannula is in the distal-most second elongate cannula extended position.

6 . The medical apparatus of claim 4 , wherein the mechanical thrombectomy whisk is proximally adjacent to the perforated region when the second elongate cannula is in at least one of the plurality of second elongate cannula extended positions.

7 . The medical apparatus of claim 1 , wherein the third elongate cannula is configured to move from an initial third elongate cannula extended position to a third elongate cannula retracted position, the third elongate cannula retracted position proximal to the initial third elongate cannula extended position, when the sheath is in the retracted sheath position and the third elongate cannula is in the third elongate cannula retracted position the mechanical thrombectomy whisk is exposed.

8 . The medical apparatus of claim 1 , wherein the third elongate cannula and fourth elongate cannula are combined into a single cannula, wherein the single cannula has a single cannula exterior surface, a single cannula side wall, a single cannula proximal end, a single cannula distal end, a central lumen, and an inflation passageway extending longitudinally through the single cannula side wall, the inflation passageway extends in parallel to the central lumen, the expandable embolic filter is connected to the single cannula exterior surface at a filter connection point, the inflatable balloon is connected to the single cannula exterior surface at a balloon connection point, the balloon connection point is proximal to the filter connection point, the inflatable balloon is in fluid communication with the inflation passageway, the second elongate cannula is disposed in the central lumen.

9 . A medical apparatus, comprising:
a sheath having a sheath lumen, the sheath movable between an initial extended sheath position and a retracted sheath position; and a thrombectomy device, the thrombectomy device disposed in the sheath lumen, the thrombectomy device including:
a first elongate cannula having a proximal end, a distal end having a distal tip, a guidewire lumen, and a perforated region, the perforated region having a plurality of perforations in fluid communication with the guidewire lumen, the perforated region proximal to the distal tip;
a second elongate cannula having a second proximal end, a second distal end, a second lumen, and a mechanical thrombectomy whisk, the first elongate cannula disposed in the second lumen, the mechanical thrombectomy whisk proximal to the distal tip, the second elongate cannula configured to rotate; and
a third elongate cannula having a third exterior surface, a third proximal end, a third distal end, a third lumen, an inflation passageway, an inflatable balloon connected to the third exterior surface, and an expandable embolic filter connected to the third exterior surface at a location distal to the inflatable balloon, the second elongate cannula disposed in the third lumen, the inflatable balloon in fluid communication with the inflation passageway.

10 . The medical apparatus of claim 9 , wherein the second elongate cannula is configured to move from an initial second elongate cannula retracted position to a plurality of second elongate cannula extended positions, the second elongate cannula is configured to move from each of the plurality of second elongate cannula extended positions to each of the plurality of second elongate cannula extended positions, the second elongate cannula is configured to move from each of the plurality of second elongate cannula extended positions to the initial second elongate cannula retracted position, wherein the initial second elongate cannula retracted position is located at a location proximal to each of the plurality of second elongate cannula extended positions.

11 . The medical apparatus of claim 10 , wherein in at least one of the plurality of second elongate cannula extended positions, the mechanical thrombectomy whisk is proximal to the perforated region.

12 . The medical apparatus of claim 10 , wherein in each of the plurality of second elongate cannula extended positions, the mechanical thrombectomy whisk is distal to the expandable embolic filter.

13 . The medical apparatus of claim 10 , wherein in the initial second elongate cannula retracted position, the mechanical thrombectomy whisk is proximal to the perforated region.

14 . The medical apparatus of claim 9 , wherein the expandable embolic filter is connected to the third exterior surface at the third distal end, the expandable embolic filter has an expandable embolic filter distal end, the third elongate cannula is movable from an initial third elongate cannula extended position to a retracted third elongate cannula position, the expandable embolic filter distal end is proximal to the mechanical thrombectomy whisk when the third elongate cannula is in the retracted third elongate cannula position, the mechanical t

Assignees

• Bard Peripheral Vascular Inc

Inventors

• Erlick Benjamin
• Gerveler Matthew
• Lewis Michael
• Millar Claire
• Sampath Kumaran Ranjani
• Simmons Brandon
• Tessmer Alexander
• Tristan Michael
• Tze David

Classifications

• A61B2090/3966

  Radiopaque markers visible in an X-ray image · CPC title

• A61B2090/376

  using X-rays, e.g. fluoroscopy · CPC title

• A61F2/013

  Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting · CPC title

• A61B2017/22084

  stone- or thrombus-dissolving · CPC title

• A61B17/22032

  having inflatable gripping elements (balloon catheters A61M25/10) · CPC title