Aqueous dispersion of (meth)acrylic polymer and polysilsesquioxane nano particles
US-2022049024-A1 · Feb 17, 2022 · US
US2021305034A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2021305034-A1 |
| Application number | US-201817057964-A |
| Country | US |
| Kind code | A1 |
| Filing date | May 29, 2018 |
| Priority date | May 29, 2018 |
| Publication date | Sep 30, 2021 |
| Grant date | — |
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A precursor ion selection processing unit ( 22 ) sequentially selects precursor ions having different mass-to-charge ratios, and causes an MS/MS spectrum data acquisition processing unit ( 23 ) to acquire MS/MS spectrum data corresponding to each precursor ion. The precursor ion selection processing unit ( 22 ) sequentially selects the precursor ion having a mass-to-charge ratio which is not included in a predetermined range with respect to a mass-to-charge ratio of the precursor ion for which the MS/MS spectrum data has already been acquired.
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1 . A mass spectrometry device comprising: an MS spectrum data acquisition processing unit that acquires MS spectrum data by ionizing a sample and performing mass spectrometry; a precursor ion selection processing unit that selects a precursor ion on the basis of the MS spectrum data; and an MS/MS spectrum data acquisition processing unit that acquires MS/MS spectrum data by cleaving the selected precursor ion and performing mass spectrometry, wherein the precursor ion selection processing unit sequentially selects precursor ions having different mass-to-charge ratios, causes the MS/MS spectrum data acquisition processing unit to acquire MS/MS spectrum data corresponding to each of the precursor ions, and sequentially selects the precursor ion having a mass-to-charge ratio which is not included in a predetermined range with respect to a mass-to-charge ratio of the precursor ion for which the MS/MS spectrum data has already been acquired. 2 . The mass spectrometry device according to claim 1 , further comprising: a display processing unit that displays the MS/MS spectrum data acquired by the MS/MS spectrum data acquisition processing unit, wherein the display processing unit displays, as the MS/MS spectrum data corresponding to an ion which is not selected as the precursor ion by the precursor ion selection processing unit, the MS/MS spectrum data corresponding to the precursor ion including the mass-to-charge ratio of the ion within the predetermined range. 3 . The mass spectrometry device according to claim 2 , wherein when the MS/MS spectrum data corresponding to the ion which is not selected as the precursor ion by the precursor ion selection processing unit is displayed, the display processing unit displays a retention time in a case of assuming that the ion is selected as the precursor ion and the MS/MS spectrum data is acquired. 4 . A mass spectrometry method comprising: an MS spectrum data acquisition step of acquiring MS spectrum data by ionizing a sample and performing mass spectrometry; a precursor ion selection step of selecting a precursor ion on the basis of the MS spectrum data; and an MS/MS spectrum data acquisition step of acquiring MS/MS spectrum data by cleaving the selected precursor ion and performing mass spectrometry, wherein the precursor ion selection step sequentially selects precursor ions having different mass-to-charge ratios, causes the MS/MS spectrum data acquisition step to acquire MS/MS spectrum data corresponding to each of the precursor ions, and sequentially selects the precursor ion having a mass-to-charge ratio which is not included in a predetermined range with respect to a mass-to-charge ratio of the precursor ion for which the MS/MS spectrum data has already been acquired. 5 . The mass spectrometry method according to claim 4 , further comprising: a display step of displaying the MS/MS spectrum data acquired by the MS/MS spectrum data acquisition step, wherein the display step displays, as the MS/MS spectrum data corresponding to an ion which is not selected as the precursor ion by the precursor ion selection step, the MS/MS spectrum data corresponding to the precursor ion including the mass-to-charge ratio of the ion within the predetermined range. 6 . The mass spectrometry method according to claim 5 , wherein when the MS/MS spectrum data corresponding to the ion which is not selected as the precursor ion by the precursor ion selection step is displayed, in the display step, a retention time in a case of assuming that the ion is selected as the precursor ion and the MS/MS spectrum data is acquired is displayed.
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