Mass spectrometry device and mass spectrometry method

US2021305034A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2021305034-A1
Application numberUS-201817057964-A
CountryUS
Kind codeA1
Filing dateMay 29, 2018
Priority dateMay 29, 2018
Publication dateSep 30, 2021
Grant date

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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Abstract

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A precursor ion selection processing unit ( 22 ) sequentially selects precursor ions having different mass-to-charge ratios, and causes an MS/MS spectrum data acquisition processing unit ( 23 ) to acquire MS/MS spectrum data corresponding to each precursor ion. The precursor ion selection processing unit ( 22 ) sequentially selects the precursor ion having a mass-to-charge ratio which is not included in a predetermined range with respect to a mass-to-charge ratio of the precursor ion for which the MS/MS spectrum data has already been acquired.

First claim

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1 . A mass spectrometry device comprising: an MS spectrum data acquisition processing unit that acquires MS spectrum data by ionizing a sample and performing mass spectrometry; a precursor ion selection processing unit that selects a precursor ion on the basis of the MS spectrum data; and an MS/MS spectrum data acquisition processing unit that acquires MS/MS spectrum data by cleaving the selected precursor ion and performing mass spectrometry, wherein the precursor ion selection processing unit sequentially selects precursor ions having different mass-to-charge ratios, causes the MS/MS spectrum data acquisition processing unit to acquire MS/MS spectrum data corresponding to each of the precursor ions, and sequentially selects the precursor ion having a mass-to-charge ratio which is not included in a predetermined range with respect to a mass-to-charge ratio of the precursor ion for which the MS/MS spectrum data has already been acquired. 2 . The mass spectrometry device according to claim 1 , further comprising: a display processing unit that displays the MS/MS spectrum data acquired by the MS/MS spectrum data acquisition processing unit, wherein the display processing unit displays, as the MS/MS spectrum data corresponding to an ion which is not selected as the precursor ion by the precursor ion selection processing unit, the MS/MS spectrum data corresponding to the precursor ion including the mass-to-charge ratio of the ion within the predetermined range. 3 . The mass spectrometry device according to claim 2 , wherein when the MS/MS spectrum data corresponding to the ion which is not selected as the precursor ion by the precursor ion selection processing unit is displayed, the display processing unit displays a retention time in a case of assuming that the ion is selected as the precursor ion and the MS/MS spectrum data is acquired. 4 . A mass spectrometry method comprising: an MS spectrum data acquisition step of acquiring MS spectrum data by ionizing a sample and performing mass spectrometry; a precursor ion selection step of selecting a precursor ion on the basis of the MS spectrum data; and an MS/MS spectrum data acquisition step of acquiring MS/MS spectrum data by cleaving the selected precursor ion and performing mass spectrometry, wherein the precursor ion selection step sequentially selects precursor ions having different mass-to-charge ratios, causes the MS/MS spectrum data acquisition step to acquire MS/MS spectrum data corresponding to each of the precursor ions, and sequentially selects the precursor ion having a mass-to-charge ratio which is not included in a predetermined range with respect to a mass-to-charge ratio of the precursor ion for which the MS/MS spectrum data has already been acquired. 5 . The mass spectrometry method according to claim 4 , further comprising: a display step of displaying the MS/MS spectrum data acquired by the MS/MS spectrum data acquisition step, wherein the display step displays, as the MS/MS spectrum data corresponding to an ion which is not selected as the precursor ion by the precursor ion selection step, the MS/MS spectrum data corresponding to the precursor ion including the mass-to-charge ratio of the ion within the predetermined range. 6 . The mass spectrometry method according to claim 5 , wherein when the MS/MS spectrum data corresponding to the ion which is not selected as the precursor ion by the precursor ion selection step is displayed, in the display step, a retention time in a case of assuming that the ion is selected as the precursor ion and the MS/MS spectrum data is acquired is displayed.

Assignees

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Classifications

  • by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode · CPC title

  • characterised by the fragmentation or other specific reaction · CPC title

  • Methods for using particle spectrometers · CPC title

  • Details · CPC title

  • Step by step routines describing the use of the apparatus (H01J49/0081 takes precedence) · CPC title

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What does patent US2021305034A1 cover?
A precursor ion selection processing unit ( 22 ) sequentially selects precursor ions having different mass-to-charge ratios, and causes an MS/MS spectrum data acquisition processing unit ( 23 ) to acquire MS/MS spectrum data corresponding to each precursor ion. The precursor ion selection processing unit ( 22 ) sequentially selects the precursor ion having a mass-to-charge ratio which is not in…
Who is the assignee on this patent?
Shimadzu Corp
What technology area does this patent fall under?
Primary CPC classification H01J49/0045. Mapped technology areas include Electricity.
When was this patent published?
Publication date Thu Sep 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 5 related publications on this page (citations in our corpus or others sharing the same primary CPC).