Quinazoline analogs as receptor tyrosine kinase inhibitors

US2021284656A9 · US · A9

Patent metadata
FieldValue
Publication numberUS-2021284656-A9
Application numberUS-201916264194-A
CountryUS
Kind codeA9
Filing dateJan 31, 2019
Priority dateAug 14, 2003
Publication dateSep 16, 2021
Grant date

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The invention includes methods of using compounds of Formula I as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

First claim

Opening claim text (preview).

What is claimed is: 1 . A method of treating gliomas, cancer of the ovary, bladder cancer, cancer of the esophagus, cancer of the uterus, prostate cancer, kidney cancer, skin cancer, cancer of the pancreas, leukemias, or lymphomas comprising administering a therapeutically effective amount of a compound selected from the group consisting of: 2 . The method of claim 1 , wherein the compound is: 3 . A method of inhibiting the activity of ErbB2 comprising administering a compound selected from the group consisting of: 4 . The method of claim 3 , wherein the compound is: 5 . A method of treating diseases or medical conditions mediated by type I receptor tyrosine kinases which comprises administering to a warm-blooded animal an effective amount of a compound selected from the group consisting of: 6 . The method of claim 5 , wherein the type I receptor tyrosine kinase is ErbB2. 7 . The method of claim 5 , wherein the compound is: 8 . The method of claim 6 , wherein the compound is:

Assignees

Inventors

Classifications

  • Organic additives · CPC title

  • Antineoplastic agents · CPC title

  • Nitrogen atoms · CPC title

  • linked by a chain containing hetero atoms as chain links · CPC title

  • linked by a chain containing hetero atoms as chain links · CPC title

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Frequently asked questions

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What does patent US2021284656A9 cover?
The invention includes methods of using compounds of Formula I as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
Who is the assignee on this patent?
Array Biopharma Inc
What technology area does this patent fall under?
Primary CPC classification C07D498/10. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Thu Sep 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) (A9). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).