Detection of allergen exposure

Patent metadata

Field	Value
Publication number	US-2021282702-A1
Application number	US-202117333710-A
Country	US
Kind code	A1
Filing date	May 28, 2021
Priority date	Dec 23, 2014
Publication date	Sep 16, 2021
Grant date	—

Abstract

One example implementation includes an extractor controller to control extraction of blood from a user; a detection fluid manager to mix the blood and a detection fluid to form magnetized test particles, the detection fluid comprising dye coated magnetic particles; a particle flow controller to remove magnetized test particles from the mixed blood and detection fluid; and an allergen detector to detect exposure to an allergen based on a color of the test particles.

First claim

1 - 15 . (canceled)

16 . An apparatus comprising:
a detection fluid container containing detection fluid comprising dye coated magnetic particles, wherein the dye coated magnetic particles comprise a dye coating including histamine antibodies that change color when exposed to histamines and antibodies of the histamines; a particle flow controller comprising a magnet or an electromagnet that removes magnetic test particles from a mixing of blood extracted from a user with the detection fluid; a photodetector to determine a color of the dye coating based on a measurement of voltage of light reflecting from the magnetic test particles; an allergen detector system comprising a processor and memory storing executable stored instructions that, when executed, cause the processor to perform operations comprising:
control a flow of the detection fluid from the detection fluid container to facilitate mixing of the blood extracted from the user and the detection fluid in a blood extraction pad to generate the magnetic test particles; and
determine a color of the magnetic test particles based on the photodetector; and
perform a blood analysis on the blood based on the color of the magnetic test particles, wherein the blood analysis determines a severity of an exposure to an allergen based on a threshold difference in the color of the magnetic test particles and a baseline measurement color due to the presence of histamines in the blood.

17 . The apparatus of claim 16 , further comprising:
a light emitter, wherein the color of the magnetic test particles is determined further based on light emitted from the light emitter.

18 . The apparatus of claim 16 , further comprising:
a blood extraction pad, wherein the mixing of the blood and the detection fluid occurs in the blood extraction pad.

19 . The apparatus of claim 16 , further comprising:
a treatment provider comprising a drug container and a treatment cannula, wherein the allergen detector system notifies the treatment provider of an exposure to an allergen based on the blood analysis, causing the treatment provider to treat the user by injecting the user with a drug from the drug container via the treatment cannula.

20 . The apparatus of claim 16 , further comprising:
a blood extractor comprising: a blood extraction pad, wherein the blood extracted from the user is received by the blood extraction pad; and an extraction cannula, wherein the blood extracted from the user is extracted by the extraction cannula.

21 . The apparatus of claim 16 , further comprising:
a waste container, wherein the blood, the detection fluid, and the magnetized test particles are stored in the waste container after the blood analysis is performed.

22 . The apparatus of claim 16 , wherein the executable instructions further cause the processor to:
perform a second blood analysis on second blood extracted from the user to confirm that an exposure to an allergen has occurred.

23 . The apparatus of claim 16 , wherein the color of the magnetic test particles are determined further based on a measurement of voltage.

24 . The apparatus of claim 16 , further comprising:
a magnet; and a valve, wherein the magnetized test particles are moved toward a location of the allergen detector system based on the magnet and the valve.

25 . The apparatus of claim 16 , wherein the particle flow controller control the flow of magnetic test particles from the detection fluid to move toward a location of the allergen detector system.

Assignees

• Hewlett Packard Entpr Dev Lp

Inventors

• Kaur Satwant
• Schmidt Larry

Classifications

• G16H50/20

  for computer-aided diagnosis, e.g. based on medical expert systems · CPC title

• G01N2800/24

  Immunology or allergic disorders · CPC title

• A61B5/411 Primary

  Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance · CPC title

• A61B5/746

  Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms · CPC title

• G01N33/52

  Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper {and including single- and multilayer analytical elements (immunological elements G01N33/54386; involving labelled immunochemicals G01N33/58; for haemoglobin or occult blood G01N33/72)} · CPC title