Antimicrobial material, layered body, antimicrobial layered body, medical member, antimicrobial material production method, antimicrobial layered body production method, and antimicrobial method

Patent metadata

Field	Value
Publication number	US-2021206136-A1
Application number	US-202117212078-A
Country	US
Kind code	A1
Filing date	Mar 25, 2021
Priority date	Sep 28, 2018
Publication date	Jul 8, 2021
Grant date	—

Abstract

An antimicrobial layered body includes: a non-metal substrate; and a metal oxide layer, in which the metal oxide layer is present on an outermost surface, the metal oxide layer contains an anion, and a total abundance ratio of at least one atom of a sulfur atom, a phosphorus atom, and a carbon atom which are derived from the anion is 1.0 atm % or more when analyzed by XPS.

First claim

What is claimed is:

1 . An antimicrobial layered body comprising a non-metal substrate and a metal oxide layer, wherein the metal oxide layer is present on an outermost surface, the metal oxide layer contains an anion, and a total abundance ratio of at least one atom of a sulfur atom, a phosphorus atom, and a carbon atom which are derived from the anion is 1.0 atm % or more when analyzed by XPS.

2 . The antimicrobial layered body according to claim 1 , wherein the anion is selected from the group consisting of SO 4 2− , PO 4 3− , C 2 O 4 2− , C 3 H 2 O 4 2− , C 4 H 4 O 5 2− , and C 6 H 5 O 7 3− .

3 . The antimicrobial layered body according to claim 1 , wherein, in the metal oxide layer present on the outermost surface, an abundance ratio of at least one atom of a sulfur atom, a phosphorus atom, and a carbon atom derived from the anion is 3.0 atm % or more.

4 . The antimicrobial layered body according to claim 1 , further comprising a metal layer.

5 . The antimicrobial layered body according to claim 4 , wherein a metal contained in the metal oxide layer and the metal layer is a valve metal.

6 . The antimicrobial layered body according to claim 5 , wherein the valve metal is aluminum.

7 . The antimicrobial layered body according to claim 5 , wherein, in the metal oxide layer present on the outermost surface, a total abundance ratio of the valve metal is 10 atm % or more when analyzed by XPS, and a total abundance ratio of a non-valve metal and a halogen atom is 1.0 atm % or less when analyzed by XPS.

8 . The antimicrobial layered body according to claim 7 , wherein the non-valve metal is at least one selected from the group consisting of silver, copper, titanium, and germanium, and the halogen atom is an iodine atom.

9 . The antimicrobial layered body according to claim 1 , wherein, in the metal oxide layer present on the outermost surface, an atom derived from the anion is a sulfur atom and an abundance ratio of an oxygen atom is 45 atm % or more when analyzed by XPS.

10 . The antimicrobial layered body according to claim 1 , wherein a total light transmittance of the metal oxide layer is 30% or more.

11 . The antimicrobial layered body according to claim 1 , wherein a thickness of the metal oxide layer is 50 nm or larger and 10 μm or smaller.

12 . The antimicrobial layered body according to claim 1 , wherein the metal oxide layer present on the outermost surface has a plurality of projection portions on the outermost surface thereof, and an average distance between adjacent projection portions is 20 to 600 nm.

13 . The antimicrobial layered body according to claim 12 , wherein the projection portion is a needle-like protrusion.

14 . An antimicrobial layered body production method which is for the antimicrobial layered body according to claim 4 , the method comprising a step of anodizing a surface of a metal layer containing 95% by mass or more of a valve metal by using a polybasic acid having a concentration of 0.04 M or higher to form the metal oxide layer.

15 . The antimicrobial layered body production method according to claim 14 , wherein a concentration of the polybasic acid is 0.3 M or higher.

16 . The antimicrobial layered body production method according to claim 14 , wherein the valve metal is aluminum, and the polybasic acid is sulfuric acid having a concentration of 3 M or higher.

17 . The antimicrobial layered body production method according to claim 16 , wherein a concentration of the sulfuric acid is 6 M or higher.

18 . An antimicrobial material comprising an oxide film of a metal having a plurality of projection portions on a surface, wherein an average distance between adjacent projection portions is 20 to 400 nm.

19 . The antimicrobial material according to claim 18 , wherein the projection portion is a needle-like protrusion.

20 . A layered body comprising a layer made of the antimicrobial material according to claim 18 .

21 . A medical member comprising the antimicrobial material according to claim 18 .

22 . An antimicrobial material production method for producing the antimicrobial material according to claim 18 , the method comprising:
forming an oxide film having a plurality of projection portions on a surface by performing, once or more times, a combination of a step of anodizing a metal base material to form an oxide film having a pore and a step of expanding a diameter of the pore.

23 . An antimicrobial method comprising:
providing the antimicrobial material according to claim 18 at a place where growth of bacteria is desired to be suppressed.

Assignees

• Mitsubishi Chem Corp

Inventors

• Murata Takaaki
• Masuda Hideki
• Yanagishita Takashi

Classifications

• C25F3/20

  of aluminium · CPC title

• B32B2255/10

  on synthetic resin layer or on natural or synthetic rubber layer · CPC title

• B32B2605/003

  Interior finishings · CPC title

• B32B15/082

  comprising vinyl resins; comprising acrylic resins · CPC title

• B32B15/088

  comprising polyamides · CPC title