Anti-paravalvular leakage component for a transcatheter valve prosthesis

Patent metadata

Field	Value
Publication number	US-2021205075-A1
Application number	US-202117210636-A
Country	US
Kind code	A1
Filing date	Mar 24, 2021
Priority date	Feb 1, 2013
Publication date	Jul 8, 2021
Grant date	—

Abstract

A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.

First claim

1 - 20 . (canceled)

21 . A transcatheter valve prosthesis comprising:
a tubular stent having a radially compressed configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve; a prosthetic valve component disposed within and secured to the tubular stent; and an anti-paravalvular leakage component including a plurality of self-expanding segments coupled to and extending from the tubular stent and an annular sealing element coupled to and covering an outer surface or an inner surface of each of the self-expanding segments, the anti-paravalvular leakage component coupled to and circumferentially surrounding an outer surface of the tubular stent, wherein the anti-paravalvular leakage component has an expanded configuration in which the self-expanding segments extend radially away from the outer surface of the tubular stent.

22 . The transcatheter valve prosthesis of claim 21 , wherein the self-expanding segments are bowed outward relative to the outer surface of the tubular stent.

23 . The transcatheter valve prosthesis of claim 22 , wherein the anti-paravalvular leakage component includes a sinusoidal patterned ring of self-expanding material that defines a plurality of peaks and a plurality of valleys, and wherein each self-expanding segment is formed to extend between a respective peak and valley of the pluralities of peaks and valleys.

24 . The transcatheter valve prosthesis of claim 21 , wherein a first end of each self-expanding segment is coupled to the outer surface of the tubular stent.

25 . The transcatheter valve prosthesis of claim 24 , wherein a second end of each self-expanding segment is coupled to the outer surface of the tubular stent.

26 . The transcatheter valve prosthesis of claim 25 , wherein the self-expanding segments curve radially away from the outer surface of the tubular stent.

27 . The transcatheter valve prosthesis of claim 21 , wherein the annular sealing element includes a membrane of impermeable material.

28 . The transcatheter valve prosthesis of claim 27 , wherein the impermeable material is a knit or woven polyester.

29 . The transcatheter valve prosthesis of claim 21 , wherein the annular sealing element is coupled to at least a portion of the tubular stent.

30 . The transcatheter valve prosthesis of claim 21 , wherein the annular sealing element is formed from a swellable material that collapses easily and expands to a larger volume after implantation.

31 . The transcatheter valve prosthesis of claim 21 , wherein the annular sealing element is formed from a compressible foam.

32 . The transcatheter valve prosthesis of claim 21 , wherein the annular sealing element is attached to the outer surface of each self-expanding segment via sutures.

33 . The transcatheter valve prosthesis of claim 21 , wherein the self-expanding segments are spaced apart in approximately equal intervals around the tubular stent.

34 . The transcatheter valve prosthesis of claim 21 , wherein the tubular stent includes a support frame of struts and openings defined between the struts.

35 . The transcatheter valve prosthesis of claim 34 , wherein each segment has a different cross-section and/or size from a strut of the tubular stent.

36 . The transcatheter valve prosthesis of claim 35 , wherein each self-expanding segment is thinner than the struts of the tubular stent.

37 . The transcatheter valve prosthesis of claim 35 , wherein each self-expanding segment has a circular cross-section and the struts of the tubular stent have a non-circular cross-section.

38 . A transcatheter valve prosthesis comprising:
a tubular stent having a radially compressed configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve, wherein the tubular stent includes a support frame of struts and openings defined between the struts; a prosthetic valve component disposed within and secured to the stent; and an anti-paravalvular leakage component including a plurality of self-expanding segments and an annular sealing element coupled to the segments, the anti-paravalvular leakage component coupled to and circumferentially surrounding an outer surface of the tubular stent, wherein the anti-paravalvular leakage component has an expanded configuration in which the self-expanding segments extend radially away from the outer surface of the tubular stent, and wherein each self-expanding segment has a different cross-section and/or size from the struts of the tubular stent.

39 . The transcatheter valve prosthesis of claim 38 , wherein each self-expanding segment is thinner than the struts of the tubular stent.

40 . The transcatheter valve prosthesis of claim 38 , wherein each self-expanding segment has a circular cross-section and the struts of the tubular stent have a non-circular cross-section.

Assignees

• Medtronic Cv Luxembourg S A R L

Inventors

• Eberhardt Carol
• Soundararajan Gopikrishnan
• Dang Kenny
• Rangwala Hussain
• Torrianni Mark
• Richardson Eric
• Garde Kshitija

Classifications

• A61F2250/0069

  Sealing means · CPC title

• A61F2230/0013

  Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped · CPC title

• A61F2220/005

  using adhesives · CPC title

• A61F2/2409 Primary

  Support rings therefor, e.g. for connecting valves to tissue (annuloplasty rings A61F2/2442) · CPC title

• A61F2/2418

  Scaffolds therefor, e.g. support stents · CPC title