Sucrose isomerases as food and nutritional supplements

Patent metadata

Field	Value
Publication number	US-2021196804-A1
Application number	US-201917269951-A
Country	US
Kind code	A1
Filing date	Aug 21, 2019
Priority date	Aug 22, 2018
Publication date	Jul 1, 2021
Grant date	—

Abstract

Sucrose isomerase is used as a nutritional supplement, or can be mixed in with a powderous food/beverage formulation. When an animal, including a human, consumes sucrose, the sucrose isomerase will act on the sucrose present in the food, and will convert the sucrose to other sugars. This results in lowering of the glycemic index of the food without changing the formulation of the food.

First claim

1 . A nutraceutical, pharmaceutical or nutritional supplement composition comprising a sucrose isomerase.

2 . A composition according to claim 1 which is suitable for humans.

3 . A composition according to claim 2 which is suitable for companion animals.

4 . A composition according to claim 1 comprising a sucrose isomerase with at least 60% identity, preferably 90%, 95%, 98%, 99%, 100% identity, to any one of the sequences of SEQ ID NO:1-6.

5 . A composition according to claim 4 comprising a sucrose isomerase with at least 60% identity, preferably 90%, 95%, 98%, 99%, 100% identity, to SEQ ID NO: 4.

6 . A method of lowering the increase of blood glucose levels in an animal, including a human ingesting sucrose, comprising administering a nutraceutical, pharmaceutical or nutritional supplement of claim 1 to the animal including a human in need thereof.

7 . A method of lowering the glycemic index of a food or feed which is consumed by a human or companion animal comprising administering to the human or companion animal a nutraceutical, pharmaceutical or nutritional supplement comprising a sucrose isomerase according to claim 1 .

8 . A method of losing weight or maintaining weight loss in a human or companion animal comprising administering to the human or companion animal a nutraceutical, pharmaceutical or nutritional supplement comprising a sucrose isomerase according to claim 1 .

9 . Use of a nutraceutical, pharmaceutical or nutritional supplement comprising a sucrose isomerase to achieve a condition in an animal, including a human, selected from the group consisting of:
a) lower the increase of blood sugar levels; b) increased endurance of an animal performing endurance exercise; c) loss of weight, or maintenance of lost weight d) lowering the glycemic index of ingested food or feed; and e) sustained energy release and/or prevention or minimization of a fast blood sugar rise and the so-called after-meal “dip” after a sucrose-containing meal.

10 . A dry food or beverage mixture comprising a sucrose isomerase.

Assignees

• Dsm Ip Assets Bv

Inventors

• Bruins Maaike Johanna
• Dekker Petrus Jacobus Theodorus
• Nooijens Jeroen Adrianus Johannes

Classifications

• A23L29/06

  Enzymes · CPC title

• A23V2200/332

  Promoters of weight control and weight loss · CPC title

• A23L33/195 Primary

  Proteins from microorganisms · CPC title

• A61K38/52 Primary

  Isomerases (5) · CPC title

• A23L33/30

  Dietetic or nutritional methods, e.g. for losing weight (A23L33/10 takes precedence) · CPC title