Composition for laminated material used for medical lubricating member, laminated material used for medical lubricating member, medical lubricating member, and medical device

Patent metadata

Field	Value
Publication number	US-2021129511-A1
Application number	US-202117147679-A
Country	US
Kind code	A1
Filing date	Jan 13, 2021
Priority date	Jul 17, 2018
Publication date	May 6, 2021
Grant date	—

Abstract

There is provided a composition for a laminated material used for a medical lubricating member, the composition including a polymer b1 including a polysiloxane structure and a crosslinkable polymer b2 having a particular reactive group that forms a crosslinked body with the polymer b1 and having a number-average molecular weight of 1000 or more. The crosslinkable polymer b2 is at least one of polysaccharides, polyethyleneimines, polyesters, polyethers, polyamides, polyurethanes, polyureas, or polyimides. There are also provided a laminated material used for a medical lubricating member and including the composition, a medical lubricating member, and a medical device.

First claim

What is claimed is:

1 . A composition for a laminated material used for a medical lubricating member, the composition comprising:
a polymer b1 including a polysiloxane structure; and a crosslinkable polymer b2 having a reactive group that forms a crosslinked body with the polymer b1, wherein the reactive group is at least one reactive group in Group I of reactive groups, the crosslinkable polymer b2 is at least one of polysaccharides, polyethyleneimines, polyesters, polyethers, polyamides, polyurethanes, polyureas, or polyimides, and the crosslinkable polymer b2 has a number-average molecular weight of 1000 or more, Group I of reactive groups hydroxy group, carboxy group, amino group, isocyanate group, oxazolinyl group, epoxy group, vinyl group, ethynyl group, sulfanyl group, azide group, trialkoxysilyl group, halogenated methyl group, and acid anhydride structure.

2 . A laminated material used for a medical lubricating member, the laminated material comprising:
a substrate a; and a layer b disposed on the substrate a, wherein the layer b is a layer including a crosslinked body formed from a polymer b1 including a polysiloxane structure and a crosslinkable polymer b2 having at least one reactive group in Group I of reactive groups, the crosslinkable polymer b2 is at least one of polysaccharides, polyethyleneimines, polyesters, polyethers, polyamides, polyurethanes, polyureas, or polyimides, and the crosslinkable polymer b2 has a number-average molecular weight of 1000 or more, Group I of reactive groups hydroxy group, carboxy group, amino group, isocyanate group, oxazolinyl group, epoxy group, vinyl group, ethynyl group, sulfanyl group, azide group, trialkoxysilyl group, halogenated methyl group, and acid anhydride structure.

3 . The laminated material used for a medical lubricating member according to claim 2 , wherein the polymer b1 is a graft polymer having the polysiloxane structure in a graft chain.

4 . The laminated material used for a medical lubricating member according to claim 2 ,
wherein the polymer b1 has a structural unit represented by formula (1) below and has at least one of a structural unit represented by formula (2) below, a structural unit represented by formula (3) below, or a structural unit represented by formula (4) below,

wherein R 1 to R 6 represent a hydrogen atom or an organic group, L 1 represents a single bond or a divalent linking group, and n1 represents 3 to 10000,

wherein R 7 and R a represent a hydrogen atom or an organic group,

wherein R 8 , R b1 , and R b2 represent a hydrogen atom or an organic group, and

wherein R 9 represents a hydrogen atom or an organic group, and R c1 to R c5 represent a hydrogen atom, a halogen atom, or an organic group.

5 . The laminated material used for a medical lubricating member according to claim 4 ,
wherein R a represents a group represented by formula (5) below or a nitrogen-containing organic group,

wherein n2 represents 1 to 10000, R 10 represents a hydrogen atom or an organic group, and * represents a bonding site.

6 . The laminated material used for a medical lubricating member according to claim 4 , wherein n1 represents 135 to 10000.

7 . The laminated material used for a medical lubricating member according to claim 2 , wherein the crosslinkable polymer b2 is at least one of polysaccharides, polyethyleneimines, polyesters, polyethers, polyamides, or polyurethanes.

8 . The laminated material used for a medical lubricating member according to claim 2 , wherein a content of a constituent component derived from the crosslinkable polymer b2 in the crosslinked body is 30 to 90 mass %.

9 . The laminated material used for a medical lubricating member according to claim 2 , wherein the layer b has a surface subjected to hydrophilic treatment.

10 . The laminated material used for a medical lubricating member according to claim 2 , wherein the substrate a is formed of at least one of a urethane resin, a silicone resin, a fluorocarbon resin, an olefin resin, or an acrylic resin.

11 . The laminated material used for a medical lubricating member according to claim 2 , wherein the substrate a is formed of a silicone resin.

12 . The laminated material used for a medical lubricating member according to claim 2 , wherein the medical lubricating member is used as a member of a medical device selected from the group consisting of a medical tube, a guide wire, an endoscope, a surgical needle, a surgical suture, forceps, an artificial blood vessel, an artificial heart, and a contact lens.

13 . A medical lubricating member comprising:
the laminated material used for a medical lubricating member according to claim 2 ; and a layer c that is disposed on the layer b constituting the laminated material and that includes a hydrophilic polymer.

14 . A medical device comprising:
the medical lubricating member according to claim 13 , wherein the medical device is selected from the group consisting of a medical tube, a guide wire, an endoscope, a surgical needle, a surgical suture, forceps, an artificial blood vessel, an artificial heart and a contact lens.

Assignees

• Fujifilm Corp

Inventors

• Inomata Sotaro

Classifications

• C08G18/8006

  with compounds of C08G18/32 · CPC title

• C08G18/61

  Polysiloxanes · CPC title

• C08F230/08

  containing silicon · CPC title

• C09D151/08

  grafted on to macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds · CPC title

• C08F283/12

  on to polysiloxanes · CPC title