Radiation Carrier and Use Thereof in an Optical Sensor

Patent metadata

Field	Value
Publication number	US-2021072141-A1
Application number	US-202017102388-A
Country	US
Kind code	A1
Filing date	Nov 23, 2020
Priority date	Jun 30, 2015
Publication date	Mar 11, 2021
Grant date	—

Abstract

A radiation carrier for carrying at least a radiation beam has, on a surface thereof, at least one excitation grating, for directing at least an excitation radiation beam directionally out of the radiation carrier, thereby illuminating a region of interest; and at least one structure for redirecting emission radiation emanating from the region of interest. Further a sensor is provided comprising at least one such radiation carrier and at least one detector, the structure being adapted for redirecting radiation from the region of interest into the at least one detector.

First claim

What is claimed is:

1 . A sensor comprising:
at least one radiation carrier comprising:
a surface;
at least one excitation grating on the surface of the radiation carrier, positioned and adapted to couple an excitation radiation beam directionally out of the radiation carrier, thereby illuminating a region of interest; and
at least one structure positioned and adapted for redirecting emission radiation emanating from the region of interest, wherein the radiation carrier is adapted for carrying at least a radiation beam; and
at least one detector, wherein the at least one structure is positioned and adapted for redirecting emission radiation from the region of interest into the at least one detector.

2 . The sensor according to claim 1 , wherein the at least one structure positioned and adapted for redirecting emission radiation is adapted to further collimate the redirected emission radiation from the region of interest to the at least one detector.

3 . The sensor according to claim 1 , wherein the at least one structure positioned and adapted for redirecting emission radiation is adapted to further focus the redirected emission radiation from the region of interest to the at least one detector.

4 . A microfluidic device comprising a sensor according to claim 1 , further comprising a substrate being transparent for at least the radiation beam wherein the region of interest is defined.

5 . A microfluidic device according to claim 4 , wherein the substrate is furthermore transparent for the redirected emission radiation.

6 . The microfluidic device according to claim 4 , wherein the substrate further comprises a microfluidic channel.

7 . The microfluidic device according to claim 6 , wherein the at least one detector is a detector array, and wherein the microfluidic channel is interlayered between the radiation carrier and the detector array.

8 . The microfluidic device according to claim 4 , further comprising:
a microfluidic chip comprising at least one microfluidic channel, wherein the at least one excitation grating is positioned and adapted to couple an excitation radiation signal directionally out of the radiation carrier thereby illuminating a pre-defined volume of the microfluidic channel, and at least one structure, positioned and adapted to redirect emission radiation origination from the pre-defined volume; and a readout device, adapted to be operatively coupled with the microfluidic chip, wherein the readout device comprises at least one detector for detecting the redirected emission radiation originating from the pre-defined volume, when the microfluidic chip and the readout device are operatively coupled.

9 . The system according to claim 8 , wherein the readout device comprises a slot for receiving the microfluidic chip.

10 . A diagnostic device comprising a sensor according to claim 1 , and an output unit for providing an output of the sensor on which a diagnosis can be based.

Assignees

• Imec Vzw

Inventors

• Vercruysse Dries

Classifications

• G01N21/645 Primary

  Specially adapted constructive features of fluorimeters · CPC title

• G01N15/1434

  Optical arrangements · CPC title

• G02B6/124

  Geodesic lenses or integrated gratings · CPC title

• G01N2021/0346

  Capillary cells; Microcells · CPC title

• G02B6/30

  for use between fibre and thin-film device · CPC title