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Methods of synthesis of (1r,2r,5r)-5-amino-2-methylcyclohexanol hydrochloride and intermediates useful therein
US2020369600A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2020369600-A1 |
| Application number | US-202016992219-A |
| Country | US |
| Kind code | A1 |
| Filing date | Aug 13, 2020 |
| Priority date | Jul 24, 2015 |
| Publication date | Nov 26, 2020 |
| Grant date | — |
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Abstract
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Provided herein are methods and intermediates for making (1R,2R,5R)-5-amino-2-methylcyclohexanol hydrochloride, which are useful for the preparation of compounds useful for the treatment of a disease, disorder, or condition associated with the JNK pathway.
First claim
Opening claim text (preview).
What is claimed is: 1 . A method for preparing a compound of formula (3), the method comprising contacting a compound of formula (1), with a compound of formula (2), in the presence of a Lewis acid in a solvent. 2 . The method of claim 1 , wherein the Lewis acid is AlCl 3 . 3 . The method of claim 1 , wherein the solvent is DCM.
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from amines with formation of carbamate groups · CPC title
containing only non-condensed rings · CPC title
by addition to unsaturated carbon-to-carbon bonds · CPC title
Separation of optical isomers · CPC title
- C07C213/02Primary
by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups · CPC title
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Frequently asked questions
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- What does patent US2020369600A1 cover?
- Provided herein are methods and intermediates for making (1R,2R,5R)-5-amino-2-methylcyclohexanol hydrochloride, which are useful for the preparation of compounds useful for the treatment of a disease, disorder, or condition associated with the JNK pathway.
- Who is the assignee on this patent?
- Celgene Corp
- What technology area does this patent fall under?
- Primary CPC classification C07C213/02. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Thu Nov 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).