System and method for sequestered wash buffer reuse
US-2024326038-A1 · Oct 3, 2024 · US
US2020338556A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2020338556-A1 |
| Application number | US-202016928980-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jul 14, 2020 |
| Priority date | Nov 24, 2015 |
| Publication date | Oct 29, 2020 |
| Grant date | — |
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A low-voltage microfluidic valve device and system for regulating the flow of fluid. One low-voltage microfluidic valve device for regulating the low of fluid includes a nano-textured dendritic metallic filament configured to grow and retract in response to a voltage. The low-voltage microfluidic valve device also includes a microfluidic channel configured to allow fluid flow, wherein the fluid flow is selectively interrupted by the growth of the nano-textured dendritic metallic filament. The low-voltage microfluidic valve device also includes a membrane positioned proximate to the fluid and configured to alter shape in response to the growth of the nano-textured dendritic metallic filament.
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1 - 10 . (canceled) 11 . A system of regulating a flow of a fluid, the system comprising: a low-voltage microfluidic valve device, the low-voltage microfluidic valve device including a first electrode and a second electrode opposite the first electrode, a microfluidic channel formed between the first electrode and the second electrode; a nano-textured dendritic metallic filament configured to grow and retract between the first electrode and the second electrode in response to a voltage applied to the first electrode and the second electrode, a parylene membrane covering the microfluidic channel and configured to alter shape in response to the growth of the nano-textured dendritic metallic filament, and the microfluidic channel configured to allow fluid flow over the parylene membrane, wherein the fluid flow is selectively interrupted by the parylene membrane when the shape of the parylene membrane is altered by the growth of the nano-textured dendritic metallic filament; and a power supply, wherein the power supply is configured to provide the voltage applied to the first electrode and the second electrode of the low-voltage microfluidic valve device. 12 . The system of claim 11 , wherein the low-voltage microfluidic valve device further includes an underlying metal and solid electrolyte. 13 . The system of claim 12 , wherein the parylene membrane is configured to isolate the fluid from the underlying metal and solid electrolyte. 14 . The system of claim 12 , wherein the underlying metal and solid electrolyte is constructed of silver-doped chalcogenide. 15 . The system of claim 11 , wherein the nano-textured dendritic metallic filament is configured to grow and retract in response to the voltage applied across the first electrode and the second electrode. 16 . The system of claim 11 , wherein the growth and retraction of the nano-textured dendritic metallic filament is based on a reversible petal effect that controls the fluid flow through the microfluidic channel. 17 . The system of claim 11 , wherein the nano-textured dentritic metallic filament is configured to grow in response to a positive voltage and wherein the nano-textured dentritic metallic filament is configured to retract in response to a negative voltage. 18 . The system of claim 11 , wherein the first electrode is constructed of silver and the second electrode is constructed of nickel, and wherein the nano-textured dendritic metallic filament is configured to grow and retract from the second electrode in response to a voltage applied across the first electrode and the second electrode.
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Chemistry or biology, e.g. "lab-on-a-chip" technology · CPC title
Electric operating means therefor · CPC title
using photolithography, e.g. etching · CPC title
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