Composition for improving, preventing or treating skin diseases comprising induced pluripotent stem cell-derived mesenchymal stem cell and exosome derived therefrom

US2020338136A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2020338136-A1
Application numberUS-201916959175-A
CountryUS
Kind codeA1
Filing dateJan 7, 2019
Priority dateJan 5, 2018
Publication dateOct 29, 2020
Grant date

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention may provide a pharmaceutical composition for preventing or treating skin diseases, a cosmetic composition for preventing or improving skin diseases, and a stem cell therapeutic agent, which comprise an induced pluripotent stem cell-derived mesenchymal stem cell (iMSC), a culture thereof, or an exosome isolated from an iMSC or iMSC culture as active ingredients. When the composition of the present invention, etc. is used, it is possible to provide a composition for improving, preventing or treating skin diseases and a stem cell therapeutic agent which have an improved immunomodulating function over conventional mesenchymal stem cells.

First claim

Opening claim text (preview).

1 .- 4 . (canceled) 5 . An exosome isolated from induced pluripotent stem cell-derived mesenchymal stem cells or a culture thereof. 6 .- 9 . (canceled) 10 . A composition comprising one or more exosomes of claim 5 . 11 . A method for treating or alleviating a skin disease in a subject in need thereof, comprising: administering to the subject a composition comprising one or more induced pluripotent stem cell (iPSC)-derived mesenchymal stem cells (iMSC) or a culture thereof 12 . The method of claim 11 , wherein the skin disease is selected from the group consisting of atopic dermatitis, contact dermatitis, and psoriasis. 13 . The method of claim 11 , wherein the subject is a mammal or a human. 14 . A method for treating or alleviating a skin disease in a subject in need thereof, comprising: administering to the subject a composition comprising one or more exosomes isolated from induced pluripotent stem cell-derived mesenchymal stem cells or a culture thereof. 15 . The method of claim 14 , wherein the skin disease is selected from the group consisting of atopic dermatitis, contact dermatitis, and psoriasis. 16 . The method of claim 14 , wherein the subject is a mammal or a human.

Assignees

Inventors

Classifications

  • A61K8/99Primary

    from microorganisms other than algae or fungi, e.g. protozoa or bacteria · CPC title

  • A61K35/545Primary

    Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells · CPC title

  • A61K35/28Primary

    Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells · CPC title

  • Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant · CPC title

  • of mammals or bird · CPC title

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What does patent US2020338136A1 cover?
The present invention may provide a pharmaceutical composition for preventing or treating skin diseases, a cosmetic composition for preventing or improving skin diseases, and a stem cell therapeutic agent, which comprise an induced pluripotent stem cell-derived mesenchymal stem cell (iMSC), a culture thereof, or an exosome isolated from an iMSC or iMSC culture as active ingredients. When the co…
Who is the assignee on this patent?
Asan Found, Univ Ulsan Found Ind Coop
What technology area does this patent fall under?
Primary CPC classification A61K8/99. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Thu Oct 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).