Fluorine coating agent having enhanced dental tubule permeability and coating endurance and method for preparing same

Patent metadata

Field	Value
Publication number	US-2020297586-A1
Application number	US-201816651619-A
Country	US
Kind code	A1
Filing date	Sep 28, 2018
Priority date	Sep 29, 2017
Publication date	Sep 24, 2020
Grant date	—

Abstract

A fluorine coating agent having enhanced dental tubule permeability and coating endurance, and a method for preparing the same. The fluorine coating agent applied on the surface of a tooth is enhanced in abrasion resistance to increase a period of time during which a coating membrane lasts, thereby preventing dental caries. Further, the curing time of the fluorine coating agent can be controlled to allow the agent to permeate and thus block the dental tubule.

First claim

1 . A fluoride coating agent with enhanced dentinal tubule penetrability and enhanced coating durability, the fluoride coating agent comprising high-molecular-weight poly(vinyl acetate) (PVAc) having a weight-average molecular weight of 300,000 to 600,000.

2 . The fluoride coating agent of claim 1 , further comprising rosin, a fluoride compound, an emulsifier, and a solvent.

3 . The fluoride coating agent of claim 2 , further comprising low-molecular-weight poly(vinyl acetate) (PVAc) having a weight-average molecular weight of 1,000 to 150,000.

4 . The fluoride coating agent of claim 2 , wherein the fluoride coating agent includes the rosin at 15 to 35 wt %, the poly(vinyl acetate) at 8 to 25 wt %, the fluoride compound at 1 to 10 wt %, the emulsifier at 01 to 15 wt %, and the solvent at 27 to 71 wt %, and
the poly(vinyl acetate) is high-molecular-weight poly(vinyl acetate) or a mixture of high-molecular-weight poly(vinyl acetate) and low-molecular-weight poly(vinyl acetate).

5 . The fluoride coating agent of claim 2 , wherein the emulsifier includes at least one nonionic surfactant selected from the group consisting of glycol ethers, sorbitan fatty acid esters, alkyl polyglycosides, and alkoxylated alcohols.

6 . The fluoride coating agent of claim 2 , wherein the fluoride coating agent has a viscosity of 800 to 1,500 cP.

7 . A method of preparing a fluoride coating agent with enhanced dentinal tubule penetrability and enhanced coating durability, the method comprising:
a first dissolution step in which high-molecular-weight poly(vinyl acetate) (PVAc) having a weight-average molecular weight of 300,000 to 600,000 is dissolved in a solvent to prepare a first solution; a second dissolution step in which rosin is dissolved in a solvent to prepare a second solution; and a mixing step in which the second solution, a fluoride compound, and an emulsifier are added to and stirred with the first solution.

8 . The method of claim 7 , wherein, in the first dissolution step, the first solution is prepared by further including low-molecular-weight poly(vinyl acetate) (PVAc) having a weight-average molecular weight of 1,000 to 150,000.

9 . The method of claim 7 , wherein the first dissolution step or the second dissolution step is performed while heating to 45 to 75° C. in boiling water.

Assignees

• Osstem Implant Co Ltd

Inventors

• Jang Il Seok
• Park Hanna
• Kim Su Kyoung
• Song Ju Dong
• Eom Tae Gwan

Classifications

• A61K6/20 Primary

  Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish · CPC title

• A61K6/887 Primary

  Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds · CPC title