Cyclic amine compound and pest control agent

Patent metadata

Field	Value
Publication number	US-2020163336-A1
Application number	US-201816636223-A
Country	US
Kind code	A1
Filing date	Aug 20, 2018
Priority date	Aug 22, 2017
Publication date	May 28, 2020
Grant date	—

Abstract

A pest control agent according to the present invention contains a compound of formula (I) (in the formula, Ar represents a substituted or unsubstituted C6-10 aryl group, R 1 represents a cyano group or a substituted or unsubstituted thiocarbamoyl group, R 2 represents a hydrogen atom, a halogeno group, a substituted or unsubstituted C1-6 alkyl group, a hydroxyl group, or a substituted or unsubstituted C1-6 alkoxy group, R 3 represents a hydrogen atom, a halogeno group, a substituted or unsubstituted C1-6 alkyl group, or the like, and Q represents a cyclic amino group) or a salt thereof.

First claim

1 . A compound of formula (I) or a salt thereof:

in the formula (I),
Ar represents a substituted or unsubstituted C6-10 aryl group,
R 1 represents a cyano group or a substituted or unsubstituted thiocarbamoyl group,
R 2 represents a hydrogen atom, a halogeno group, a substituted or unsubstituted C1-6 alkyl group, a hydroxyl group, or a substituted or unsubstituted C1-6 alkoxy group,
R 3 represents a hydrogen atom, a halogeno group, a substituted or unsubstituted C1-6 alkyl group, a substituted or unsubstituted C3-8 cycloalkyl group, a hydroxyl group, a substituted or unsubstituted C1-6 alkoxy group, a substituted or unsubstituted C6-10 aryl group, or a substituted or unsubstituted 5- or 6-membered heteroaryl group,
Q represents a cyclic amino group of formula (II-a), a cyclic amino group of formula (II-b), or a cyclic amino group of formula (II-c):

in the formulae, an arrow indicates a binding position,
p 1 indicates a number of methylenes in parentheses and is 0 or 1,
p 2 indicates a number of methylenes in parentheses and is an integer of 0 to 2,
X 1 indicates a substituent on the cyclic amino group, and is a halogeno group, a substituted or unsubstituted C1-6 alkyl group, a hydroxyl group, a substituted or unsubstituted C1-6 alkylsulfonyloxy group, or a substituted or unsubstituted C1-6 alkylthio group,
m indicates a number of X 1 and is an integer of 0 to 4,
X 2 represents a hydrogen atom, a halogeno group, a substituted or unsubstituted C1-6 alkyl group, a hydroxyl group, or a substituted or unsubstituted C1-6 alkoxy group,
Y represents a halogeno group, a substituted or unsubstituted C1-6 alkyl group, a substituted or unsubstituted C2-6 alkenyl group, a substituted or unsubstituted C1-6 alkoxy group, a substituted or unsubstituted C1-6 alkylcarbonyl group, a substituted or unsubstituted C1-6 alkoxycarbonyl group, a thiocarbamoyl group, a substituted or unsubstituted C1-6 alkylthio group, a substituted or unsubstituted C1-6 alkylsulfinyl group, a substituted or unsubstituted C1-6 alkylsulfonyl group, a substituted or unsubstituted C3-8 cycloalkyl group, a substituted or unsubstituted C6-10 arylcarbonyl group, a group of R a O—N═CR b —, a group of R c CONR d —, a group of R c COCH 2 NR d —, a group of R e SO 2 NR f —, a group of R g R h N—CO—, a group of R g R h N—SO 2 —, or a cyanothio group,
R a represents a hydrogen atom or a substituted or unsubstituted C1-6 alkyl group,
R b represents a hydrogen atom or a substituted or unsubstituted C1-6 alkyl group,
R c represents a substituted or unsubstituted C1-6 alkyl group, a substituted or unsubstituted C1-6 alkoxy group, or a substituted or unsubstituted C6-10 aryl group,
R d represents a hydrogen atom or a substituted or unsubstituted C1-6 alkyl group,
R c and R d may be combined to form a substituted or unsubstituted C3-6 alkylene group, a substituted or unsubstituted C2-6 alkyleneoxy group, or a substituted or unsubstituted C1-6 alkyleneoxy C1-6 alkylene group,
R e represents a substituted or unsubstituted C1-6 alkyl group, or a substituted or unsubstituted C6-10 aryl group,
R f represents a hydrogen atom or a substituted or unsubstituted C1-6 alkyl group,
R e and R f may be combined to form a substituted or unsubstituted C3-6 alkylene group,
R g represents a substituted or unsubstituted C1-6 alkyl group, a substituted or unsubstituted C1-6 alkoxy group, a substituted or unsubstituted C6-10 aryl group, or a substituted or unsubstituted C1-6 alkylsulfonyl group,
R h represents a hydrogen atom or a substituted or unsubstituted C1-6 alkyl group,
R g and R h may be combined to form a substituted or unsubstituted C3-6 alkylene group,
Z represents an oxo group, a group of G b -O—N═, a substituted or unsubstituted C2-6 alkylene group, a group of —O-G a -, a group of —O-G a -O—, a group of —O—CO-G a -, a group of -G a -O-G a -, a group of —NG b -CO-G a -, a group of —CO—NG b -G a -, or a group of -G-NG b -CO-G a -,
G a each independently represents a substituted or unsubstituted C1-6 alkylene group, G b each independently represents a substituted or unsubstituted C1-6 alkyl group,
Y′ represents a substituted or unsubstituted C1-6 alkylcarbonyl group, a substituted or unsubstituted C1-6 alkoxycarbonyl group, a group of R g′ R h N—CO—, a group of R g′ R h N—CS—, a group of R g′ R h N—CO—CO—, a substituted or unsubstituted C1-6 alkylsulfonyl group, or a group of R g′ R h N—SO 2 —,
R g′ represents a substituted or unsubstituted C1-6 alkyl group, a substituted or unsubstituted C1-6 alkoxy group, or a substituted or unsubstituted C6-10 aryl group, and
R g′ and R h may be combined to form a substituted or unsubstituted C3-6 alkylene group.

2 . The compound of formula (I) or the salt thereof according to claim 1 , wherein Q is a cyclic amino group of the formula (II-a), Y represents a substituted C1-6 alkyl group, a substituent on the substituted C1-6 alkyl group is a halogeno group, a hydroxyl group, a C1-6 alkoxy group, a C1-6 haloalkoxy group, a C1-6 alkylthio group, a C1-6 alkylsulfinyl group, a C1-6 alkylsulfonyl group, a C1-6 haloalkylthio group, a C1-6 haloalkylsulfinyl group, a C1-6 haloalkylsulfonyl group, a substituted or unsubstituted C6-10 aryl group, a substituted or unsubstituted C6-10 aryloxy group, a substituted or unsubstituted 5- or 6-membered heteroaryl group, a substituted or unsubstituted 5- or 6-membered heteroaryloxy group, a S—C1-6 alkylsulfonimidoyl group, a N-cyano-S—C1-6 alkylsulfonimidoyl group, a carboxyl group, a C1-6 alkylcarbonyl group, a C1-6 alkoxycarbonyl group, a C1-6 alkylcarbonylthio group, a group of R j R k N—, a group of R j R k N—CO—, a group of R j R k N—SO 2 —, a group of R m CONR n —, a group of R m SO 2 NR n —, a group of R p O—N═CR q —, or a cyano group,
R j represents a C1-6 alkyl group or a C1-6 alkoxy group, R k represents a hydrogen atom or a C1-6 alkyl group, R j and R k may be combined to form a C3-6 alkylene group,
R m represents a C1-6 alkyl group, R n represents a hydrogen atom or a C1-6 alkyl group,
R p represents a C1-6 alkyl group, and R q represents a hydrogen atom or a C1-6 alkyl group.

3 . A pest control agent comprising, as an active ingredient thereof, at least one selected from the group consisting of a compound and a salt thereof of claim 1 .

4 . An insecticide or acaricide comprising, as an active ingredient thereof, at least one selected from the group consisting of a compound and a salt thereof of claim 1 .

5 . An ectoparasite control or expellant agent comprising, as an active ingredient thereof, at least one selected from the group consisting of a compound and a salt thereof of claim 1 .

Assignees

• Nippon Soda Co

Inventors

• NISHIO Fumiya
• Iwata Jun
• Makino Satoshi
• Iwasa Takao
• Hirata Koichi
• Hamamoto Isami

Classifications

• A01N43/80

  five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2 · CPC title

• A61K31/5377

  not condensed and containing further heterocyclic rings, e.g. timolol · CPC title

• C07D491/107

  with only one oxygen atom as ring hetero atom in the oxygen-containing ring · CPC title

• A61K31/4545

  containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine · CPC title

• C07D401/14

  containing three or more hetero rings · CPC title