Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
US-8993761-B2 · Mar 31, 2015 · US
US2020123110A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2020123110-A1 |
| Application number | US-201916718281-A |
| Country | US |
| Kind code | A1 |
| Filing date | Dec 18, 2019 |
| Priority date | Sep 25, 2001 |
| Publication date | Apr 23, 2020 |
| Grant date | — |
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The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the anhydrous aripiprazole crystals is stored for an extended period.
Opening claim text (preview).
1 . Hydrate A of aripiprazole having a powder x-ray diffraction spectrum comprising characteristic peaks at 2θ=12.6°, 15.4°, 17.3°, 18.0°, 18.6°, 22.5°, and 24.8° using a Cu K α x-ray.
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