Low hygroscopic aripiprazole drug substance and processes for the preparation thereof

US2020123110A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2020123110-A1
Application numberUS-201916718281-A
CountryUS
Kind codeA1
Filing dateDec 18, 2019
Priority dateSep 25, 2001
Publication dateApr 23, 2020
Grant date

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the anhydrous aripiprazole crystals is stored for an extended period.

First claim

Opening claim text (preview).

1 . Hydrate A of aripiprazole having a powder x-ray diffraction spectrum comprising characteristic peaks at 2θ=12.6°, 15.4°, 17.3°, 18.0°, 18.6°, 22.5°, and 24.8° using a Cu K α x-ray.

Assignees

Inventors

Classifications

  • Antidepressants · CPC title

  • attached in position 2 or 4 · CPC title

  • Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates · CPC title

  • A61K9/1652Primary

    Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin (homeopathic globules A61K9/1623) · CPC title

  • Hypnotics; Sedatives · CPC title

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Frequently asked questions

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What does patent US2020123110A1 cover?
The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the anhydrous aripiprazole crystals is stored for an extended period.
Who is the assignee on this patent?
Otsuka Pharma Co Ltd
What technology area does this patent fall under?
Primary CPC classification A61K9/1652. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Thu Apr 23 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).