Compositions for a dietary supplement to manage senescent cells
US-2024390346-A1 · Nov 28, 2024 · US
US2020121639A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2020121639-A1 |
| Application number | US-201816490554-A |
| Country | US |
| Kind code | A1 |
| Filing date | Mar 2, 2018 |
| Priority date | Mar 3, 2017 |
| Publication date | Apr 23, 2020 |
| Grant date | — |
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The present invention is drawn to methods for effecting weight loss, e.g.. in the treatment of obesity and related conditions, including conditions associated with and/or caused by obesity per se.
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1 . A method of treating obesity comprising administering to a patient in need, a dosage of 1.0-200.0 mg of LIK066, or salt thereof. 2 . The method according to claim 1 , wherein the dosage is selected from the group consisting of 2.5 mg, 5.0 mg, 10.0 mg, 25.0 mg, 35 mg, and 50 mg. 3 . The method according to claim 1 , wherein the dosage is administered once a day. 4 . The method according to claim 1 , wherein the dosage is administered twice a day. 5 . The method according to claim 1 , wherein the administered dosage ameliorates the side effects of diarrhea. 6 . A method for effecting weight loss in a patient having a body mass index of at least 25 kg/m 2 , comprising administering an escalating unit dosage form comprising administering to a patient in need, a dosage of 1.0-200.0 mg of LIK066, or salt thereof. 7 . The method of claim 6 , wherein the subject has a body mass index between 25 kg/m 2 and 29.9 kg/m 2 . 8 . The method of claim 6 , wherein the subject has a body mass index of at least 30 kg/m 2 . 9 . The method of claim 1 , wherein the escalating unit dosage form is formulated for oral administration. 10 . The method of claim 1 , wherein the weight loss is effective to achieve a reduction of at least about 10% of body weight. 11 . The method according to claim 1 , wherein the dosage is administered once a day. 12 . The method according to claim 1 , wherein the dosage is administered twice a day. 13 . The method according to claim 1 , wherein the administered dosage ameliorates the side effects of diarrhea.
having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel · CPC title
Anorexiants; Antiobesity agents · CPC title
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