Sglt1/2 inhibitor lik066 for treating obesity

US2020121639A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2020121639-A1
Application numberUS-201816490554-A
CountryUS
Kind codeA1
Filing dateMar 2, 2018
Priority dateMar 3, 2017
Publication dateApr 23, 2020
Grant date

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  1. Title

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  2. Abstract

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  4. Key dates

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  5. First independent claim

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Abstract

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The present invention is drawn to methods for effecting weight loss, e.g.. in the treatment of obesity and related conditions, including conditions associated with and/or caused by obesity per se.

First claim

Opening claim text (preview).

1 . A method of treating obesity comprising administering to a patient in need, a dosage of 1.0-200.0 mg of LIK066, or salt thereof. 2 . The method according to claim 1 , wherein the dosage is selected from the group consisting of 2.5 mg, 5.0 mg, 10.0 mg, 25.0 mg, 35 mg, and 50 mg. 3 . The method according to claim 1 , wherein the dosage is administered once a day. 4 . The method according to claim 1 , wherein the dosage is administered twice a day. 5 . The method according to claim 1 , wherein the administered dosage ameliorates the side effects of diarrhea. 6 . A method for effecting weight loss in a patient having a body mass index of at least 25 kg/m 2 , comprising administering an escalating unit dosage form comprising administering to a patient in need, a dosage of 1.0-200.0 mg of LIK066, or salt thereof. 7 . The method of claim 6 , wherein the subject has a body mass index between 25 kg/m 2 and 29.9 kg/m 2 . 8 . The method of claim 6 , wherein the subject has a body mass index of at least 30 kg/m 2 . 9 . The method of claim 1 , wherein the escalating unit dosage form is formulated for oral administration. 10 . The method of claim 1 , wherein the weight loss is effective to achieve a reduction of at least about 10% of body weight. 11 . The method according to claim 1 , wherein the dosage is administered once a day. 12 . The method according to claim 1 , wherein the dosage is administered twice a day. 13 . The method according to claim 1 , wherein the administered dosage ameliorates the side effects of diarrhea.

Assignees

Inventors

Classifications

  • A61K31/357Primary

    having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel · CPC title

  • Anorexiants; Antiobesity agents · CPC title

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What does patent US2020121639A1 cover?
The present invention is drawn to methods for effecting weight loss, e.g.. in the treatment of obesity and related conditions, including conditions associated with and/or caused by obesity per se.
Who is the assignee on this patent?
Novartis Ag
What technology area does this patent fall under?
Primary CPC classification A61K31/357. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Thu Apr 23 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).