Hierarchical magnetic nanoparticle-enzyme mesoporous assemblies embedded in macroporous scaffolds

Patent metadata

Field	Value
Publication number	US-2020002698-A1
Application number	US-201916454714-A
Country	US
Kind code	A1
Filing date	Jun 27, 2019
Priority date	Oct 5, 2012
Publication date	Jan 2, 2020
Grant date	—

Abstract

A hierarchical catalyst composition comprising a continuous or particulate macroporous scaffold in which is incorporated mesoporous aggregates of magnetic nanoparticles, wherein an enzyme is embedded in mesopores of the mesoporous aggregates of magnetic nanoparticles. Methods for synthesizing the hierarchical catalyst composition are also described. Also described are processes that use the recoverable hierarchical catalyst composition for depolymerizing lignin remediation of water contaminated with aromatic substances, polymerizing monomers by a free-radical mechanism, epoxidation of alkenes, halogenation of phenols, inhibiting growth and function of microorganisms in a solution, and carbon dioxide conversion to methanol. Further described are methods for increasing the space time yield and/or total turnover number of a liquid-phase chemical reaction that includes magnetic particles to facilitate the chemical reaction, the method comprising subjecting the chemical reaction to a plurality of magnetic fields of selected magnetic strength, relative position in the chemical reaction, and relative motion.

First claim

1 .- 22 . (canceled)

23 . A method for epoxidation reactions of alkenes, the method comprising reacting alkenes in the presence of oxygen with a hierarchical catalyst composition comprising a continuous macroporous scaffold in which is incorporated self-assembled mesoporous aggregates of magnetic nanoparticles containing an oxygen-transfer enzyme embedded in mesopores of said mesoporous aggregates of magnetic nanoparticles, to produce an alkene oxide.

24 . The method of claim 23 , wherein said oxygen-transfer enzyme is a chloroperoxidase or a lipase.

25 .- 39 . (canceled)

40 . The method of claim 23 , further comprising magnetic particles, not belonging to said mesoporous aggregates of magnetic nanoparticles, embedded in said continuous macroporous scaffold.

41 . The method of claim 23 , wherein said continuous macroporous scaffold has a polymeric composition.

42 . The method of claim 23 , wherein said continuous macroporous scaffold has macropores having a pore size greater than 50 nm.

43 . The method of claim 23 , wherein said continuous macroporous scaffold has macropores having a pore size of at least 200 nm.

44 . The method of claim 23 , wherein said continuous macroporous scaffold has macropores having a pore size up to 100 nm.

45 . The method of claim 23 , wherein said mesopores have a size of at least 1 nm and up to 50 nm.

Assignees

• Univ Cornell

Inventors

• Corgie Stephane C
• Duan Xiaonan
• Giannelis Emmanuel
• Aneshansley Daniel
• Walker Larry P

Classifications

• B01J19/12 Primary

  employing electromagnetic waves · CPC title

• C12N11/089

  obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds · CPC title

• B01J2219/0854

  employing electromagnets · CPC title

• B01J37/02

  Impregnation, coating or precipitation ({B01J37/0009 and B01J37/0018 take precedence } ; protection by coating B01J33/00) · CPC title

• C12P7/22

  aromatic · CPC title