Systems, methods, and devices for developing patient-specific medical treatments, operations, and procedures

Patent metadata

Field	Value
Publication number	US-2019380782-A1
Application number	US-201916404276-A
Country	US
Kind code	A1
Filing date	May 6, 2019
Priority date	Dec 12, 2016
Publication date	Dec 19, 2019
Grant date	—

Abstract

Certain systems, methods, and devices described herein are configured to dynamically model a patient area for surgery and/or other treatment, dynamically identify one or more features and/or characteristics thereon such as the length and/or elasticity of the posterior longitudinal ligament (PLL), dynamically allow modification of the model, dynamically limit and/or assist in modification of the model, and/or dynamically generate guidelines for generation of patient-specific implants and/or treatment kits for a specific patient.

First claim

What is claimed is:

1 . A computer-implemented method for producing a patient-specific spinal implant, the method comprising:
receiving, by a computer system, one or more pre-operative medical images of a spine of a patient; identifying, through the computer system, a posterior longitudinal ligament of the spine on the one or more pre-operative medical images; determining, by the computer system, a length of the posterior longitudinal ligament and a value for ligament elasticity of the posterior longitudinal ligament based on the identified posterior longitudinal ligament, wherein the value for ligament elasticity is derived based on a variance among lengths of a flexion line, extension line, and neutral line; determining, by the computer system, a recommended limit of correction of the spine based at least in part on the determined length of the posterior longitudinal ligament and the value for ligament elasticity of the posterior longitudinal ligament; automatically detecting, by the computer system, one or more vertebrae on the one or more pre-operative medical images of the spine; receiving, by the computer system, one or more modifications to a vertebra of the spine on the one or more pre-operative medical images, wherein the one or more modifications comprise at least one or more of displacement or rotation of the vertebra; dynamically determining, by the computer system, whether the one or more modifications to the vertebra is within the determined recommended limit of correction of the spine; dynamically updating, by the computer system, the one or more pre-operative medical images upon determination that the one or more modifications to the vertebra is within the determined recommended limit of correction of the spine; generating, by the computer system, one or more desired post-operative medical images of the spine based at least in part on the dynamically updated one or more pre-operative medical images; determining, by the computer system, one or more specifications of one or more patient-specific spinal implants for the patient based at least in part on the generated one or more desired post-operative medical images of the spine; and transmitting, by the computer system, the one or more specifications of the one or more patient-specific spinal implants to a spinal implant production system for producing the one or more patient-specific spinal implants, wherein the computer system comprises a computer processor and an electronic storage medium.

2 . The method of claim 1 , wherein the posterior longitudinal ligament is automatically identified by the computer system.

3 . The method of claim 1 , wherein the posterior longitudinal ligament is identified by a user tracing the posterior longitudinal ligament on the one or more pre-operative medical images of the spine.

4 . The method of claim 1 , further comprising generating an alert, by the computer system, upon determination that the one or more modifications to the vertebra is not within the determined recommended limit of correction of the spine.

5 . The method of claim 1 , wherein the one or more vertebrae is automatically detected on the one or more pre-operative medical images of the spine based at least in part on edge detection.

6 . The method of claim 1 , wherein the one or more pre-operative medical images comprises an x-ray image of the spine of the patient in one or more of a flexion, extension, or neutral posture.

7 . The method of claim 1 , wherein the one or more pre-operative medical images comprises one or more of an x-ray image, a CT image, or an MRI image.

8 . The method of claim 1 , further comprising scaling the one or more pre-operative medical images.

9 . The method of claim 8 , wherein the scaling is based at least in part on a reference point or object of the one or more pre-operative medical images.

10 . The method of claim 1 , wherein the one or more patient-specific spinal implants comprises one or more of a spinal rod, intervertebral spacer, cage, or screw for use in spinal surgery.

11 . A system for producing a patient-specific spinal implant, the system comprising:
one or more computer readable storage devices configured to store a plurality of computer executable instructions; and one or more hardware computer processors in communication with the one or more computer readable storage devices and configured to execute the plurality of computer executable instructions in order to cause the system to:
receive one or more pre-operative medical images of a spine of a patient;
identify a posterior longitudinal ligament of the spine on the one or more pre-operative medical images;
determine a length of the posterior longitudinal ligament and a value for ligament elasticity of the posterior longitudinal ligament based on the identified posterior longitudinal ligament, wherein the value for ligament elasticity is derived based on a variance among lengths of a flexion line, extension line, and neutral line;
determine a recommended limit of correction of the spine based at least in part on the determined length of the posterior longitudinal ligament and the value for ligament elasticity of the posterior longitudinal ligament;
automatically detect one or more vertebrae on the one or more pre-operative medical images of the spine;
receive one or more modifications to a vertebra of the spine on the one or more pre-operative medical images, wherein the one or more modifications comprise at least one or more of displacement or rotation of the vertebra;
dynamically determine whether the one or more modifications to the vertebra is within the determined recommended limit of correction of the spine;
dynamically update the one or more pre-operative medical images upon determination that the one or more modifications to the vertebra is within the determined recommended limit of correction of the spine;
generate one or more desired post-operative medical images of the spine based at least in part on the dynamically updated one or more pre-operative medical images;
determine one or more specifications of one or more patient-specific spinal implants for the patient based at least in part on the generated one or more desired post-operative medical images of the spine; and
transmit the one or more specifications of the one or more patient-specific spinal implants to a spinal implant production system for producing the one or more patient-specific spinal implants.

12 . The system of claim 11 , wherein the posterior longitudinal ligament is automatically identified by the system.

13 . The system of claim 11 , wherein the posterior longitudinal ligament is identified by the system based at least in part on user input, wherein the user input comprises tracing the posterior longitudinal ligament on the one or more pre-operative medical images of the spine.

14 . The system of claim 11 , wherein the system is further caused to generate an alert upon determination that the one or more modifications to the vertebra is not within the determined recommended limit of correction of the spine.

15 . The system of claim 11 , wherein the one or more vertebrae is automatically detected on the one or more pre-operative medical images of the spine based at least in part on edge detection.

16 . The system of claim 11 , wherein the one or more pre-operative medical images comprises an x-ray image of the spine of the patient in one or more of a flexion, extension, or neutral posture.

17 . The system of claim 11 , wherein the one or more pre-operative medical images comprises one

Assignees

• Medicrea Int

Inventors

• Mcafee Paul C
• Dobbs Elliott
• Mosnier Thomas

Classifications

• A61B2017/568

  produced with shape and dimensions specific for an individual patient · CPC title

• G06T2207/10088

  Magnetic resonance imaging [MRI] · CPC title

• A61B2034/108

  Computer aided selection or customisation of medical implants or cutting guides · CPC title

• G06T2207/30012

  Spine; Backbone · CPC title

• A61B2034/102

  Modelling of surgical devices, implants or prosthesis · CPC title