Microfluidic device

Patent metadata

Field	Value
Publication number	US-2019366341-A1
Application number	US-201616310529-A
Country	US
Kind code	A1
Filing date	Dec 13, 2016
Priority date	Jun 21, 2016
Publication date	Dec 5, 2019
Grant date	—

Abstract

The present invention may provide a microfluidic device including a rotatable body; a first chamber positioned in a direction of an inner wall of the body; a second chamber positioned in a direction of an outer wall of the body from the first chamber; and a backflow prevention unit, and wherein a fluid is transferred from the first chamber to the second chamber, and wherein the backflow prevention unit prevents a backflow of the fluid from the second chamber to the first chamber.

First claim

1 . A microfluidic device comprising:
a rotatable body; a first chamber positioned in a direction of an inner wall of the body; a second chamber positioned in a direction of an outer wall of the body from the first chamber; and a backflow prevention unit, and wherein a fluid is transferred from the first chamber to the second chamber, and wherein the backflow prevention unit prevents a backflow of the fluid from the second chamber to the first chamber.

2 . The microfluidic device of claim 1 , wherein:
the backflow prevention unit includes a moisture absorbent positioned in the second chamber and capable of absorbing a filtered fluid.

3 . The microfluidic device of claim 2 , wherein:
the second chamber has a shape having at least one end portion protruding toward a center of the body, and includes the moisture absorbent in the end portion of the second chamber such that a moisture absorption is possible in a direction opposite to a centrifugal force.

4 . The microfluidic device of claim 2 , wherein:
the moisture absorbent is in a form of powder, and fixed to a support.

5 . (canceled)

6 . The microfluidic device of claim 4 , wherein:
in the second chamber, the moisture absorbent fixed to the support is stacked.

7 . The microfluidic device of claim 6 , wherein:
the support includes polyethylene, polyester, nylon or a combination thereof.

8 . The microfluidic device of claim 2 , wherein:
the moisture absorbent includes natural fibers, acrylonitrile, silica gel, calcium chloride, acrylamide, or combinations thereof.

9 . The microfluidic device of claim 2 , wherein:
the body is a cylindrical structure rotatable with respect to a center

10 . The microfluidic device of claim 2 , wherein:
the second chamber includes an air hole connected to outside air.

11 . (canceled)

12 . The microfluidic device of claim 1 , wherein:
the backflow prevention unit includes a first micro flow channel and a second micro flow channel sequentially positioned between the first chamber and the second chamber, wherein the second micro flow channel has a shape in which a direction in which the fluid flows in from the first micro flow channel to the second micro flow channel and a direction in which the fluid flows out from the second micro flow channel to the second chamber are different with respect to a flow direction of the fluid, and wherein a wall having no permeability to the fluid is positioned between the second micro flow channel and the second chamber.

13 . The microfluidic device of claim 12 , wherein:
in the second micro flow channel, an angle formed by the direction in which the fluid flows in from the first micro flow channel to the second micro flow channel and the direction in which the fluid flows out from the second micro flow channel to the second chamber is more than 0° and less than or equal to 180°.

14 . (canceled)

15 . (canceled)

16 . (canceled)

17 . The microfluidic device of claim 12 , further comprising:
a third chamber positioned in a direction of the center of the body from the second chamber and connected to the second chamber, wherein the third chamber further includes a structure, at one end portion to which the third chamber and the second chamber are connected, protruding in a direction of the inside of the third chamber.

18 . (canceled)

19 . (canceled)

20 . The microfluidic device of claim 1 , wherein:
the backflow prevention unit includes a fourth chamber positioned between the first chamber and the second chamber and blocked from outside air; a third micro flow channel positioned between the first chamber and the fourth chamber; and a fourth micro flow channel positioned between the fourth chamber and the second chamber.

21 . The microfluidic device of claim 20 , wherein:
the fourth chamber is in a form of a column in a direction perpendicular to a fluid flow direction in the third micro flow channel and the fourth micro flow channel

22 . (canceled)

23 . (canceled)

24 . The microfluidic device of claim 20 , wherein:
a diameter of the third micro flow channel is equal to or more than 0.01 mm and equal to or less than 100 mm, and a diameter of the fourth micro flow channel is equal to or more than 0.01 mm and equal to or less than 100 mm.

25 . (canceled)

26 . (canceled)

27 . The microfluidic device of claim 20 , wherein:
the second chamber includes a moisture absorbent capable of absorbing a fluid filtered in the first chamber

28 . The microfluidic device of claim 27 , wherein:
the second chamber has a shape having at least one end portion protruding toward a center of the body, and includes the moisture absorbent in the end portion of the second chamber such that a moisture absorption is possible in a direction opposite to a centrifugal force.

29 . The microfluidic device of claim 20 , further comprising:
a second micro flow channel positioned between the fourth micro flow channel and the second chamber and connecting the fourth micro flow channel and the second chamber wherein the second micro flow channel has a shape in which a direction in which the fluid flows in from the fourth micro flow channel to the second micro flow channel and a direction in which the fluid flows out from the second micro flow channel to the second chamber are different with respect to a flow direction of the fluid, and wherein a wall having no permeability to the fluid is positioned between the second micro flow channel and the second chamber.

30 . The microfluidic device of claim 29 , wherein:
in the second micro flow channel, an angle formed by the direction in which the fluid flows in from the fourth micro flow channel to the second micro flow channel and the direction in which the fluid flows out from the second micro flow channel to the second chamber is equal to or more than 30°.

31 . The microfluidic device of claim 30 , further comprising:
a third chamber positioned in a direction of the center of the body from the second chamber and connected to the second chamber,. wherein the third chamber further includes a structure, at one end portion to which the third chamber and the second chamber are connected, protruding in a direction of the inside of the third chamber.

32 . (canceled)

Assignees

• Ulsan Nat Inst Science & Tech Unist
• Clinomics Co

Inventors

• Cho Yoon Kyoung
• Kim Tae-Hyeong
• Lee Kyusang
• Park Heechul

Classifications

• B01L2300/12

  Specific details about materials · CPC title

• B01L2300/0858

  Side walls · CPC title

• B01L2200/141

  Preventing contamination, tampering · CPC title

• B01L2200/0652

  Sorting or classification of particles or molecules · CPC title

• B01L2300/0681

  Filter · CPC title