Analysis Apparatus

US2019329240A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2019329240-A1
Application numberUS-201615998963-A
CountryUS
Kind codeA1
Filing dateFeb 17, 2016
Priority dateFeb 17, 2016
Publication dateOct 31, 2019
Grant date

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A conventional solution exchanging method in a next-generation sequencer needs a reagent amount four or more times greater than an in-flow cell flow passage volume in order to efficiently promote a chemical reaction by replacing a reagent A in the flow cell with a new reagent B. Thus, the reagent consumption amount increases, and the cost is high. Meanwhile, an analysis apparatus according to the present invention is provided with: a flow cell used for analyzing samples; a sample container for containing a sample; a reagent container for containing a reagent; and a pressure generation mechanism for feeding the sample and the reagent to the flow cell through the flow passage, and also has an atmospheric opening in the flow passage of the flow cell on the upstream side.

First claim

Opening claim text (preview).

1 . to 15 . (canceled) 16 . An analysis apparatus comprising: a flow cell used for analyzing samples; a sample container for containing a sample; a reagent container for containing a reagent; and a pressure generation mechanism for feeding the sample and the reagent to the flow cell through the flow passage, wherein an atmospheric opening is provided in the flow passage of the flow cell on the upstream side, wherein a branch portion for branching the flow passage is provided on the downstream side of the flow cell, the pressure generation mechanism is provided on one side of the flow passage branched by the branch portion, and a second pressure generation mechanism is provided on the other side, and wherein segmental air is sandwiched between the reagents and the reagents are fed. 17 . The analysis apparatus according to claim 16 , wherein the pressure generation mechanism is a syringe, and the second pressure generation mechanism is a pump. 18 . The analysis apparatus according to claim 16 , wherein both the pressure generation mechanism and the second pressure generation mechanism are syringes. 19 . The analysis apparatus according to claim 16 , wherein the pressure generation mechanism is a syringe. 20 . The analysis apparatus according to claim 16 , wherein the atmospheric opening is provided in the vicinity of the flow cell. 21 . The analysis apparatus according to claim 16 , wherein the branch portion is provided in the vicinity of the flow cell. 22 . An analysis apparatus comprising: a flow cell used for analyzing samples; a sample container for containing a sample; a reagent container for containing a reagent; a pressure generation mechanism for feeding the sample and the reagent to the flow cell through the flow passage; a merging portion in which a flow passage through which the sample and the reagent flow and another flow passage are merged with each other on the flow passage on the upstream side of the flow cell; and a second pressure generation mechanism provided on the other flow passage, wherein segmental air is sandwiched between the reagents and the reagents are fed. 23 . The analysis apparatus according to claim 22 , wherein the second pressure generation mechanism is a pump. 24 . The analysis apparatus according to claim 22 , wherein the second pressure generation mechanism is a syringe. 25 . The analysis apparatus according to claim 22 , wherein a branch portion for branching the flow passage is provided on the downstream side of the flow cell, the pressure generation mechanism is provided on one side of the flow passage branched by the branch portion, and a third pressure generation mechanism is provided on the other side. 26 . The analysis apparatus according to claim 25 , wherein the third pressure generation mechanism is a pump. 27 . The analysis apparatus according to claim 25 , wherein the third pressure generation mechanism is a syringe. 28 . The analysis apparatus according to claim 25 , wherein the branch portion is provided in the vicinity of the flow cell. 29 . The analysis apparatus according to claim 22 , wherein the merging portion is provided in the vicinity of the flow cell.

Assignees

Inventors

Classifications

  • Cells for testing reactions, e.g. containing reagents · CPC title

  • Washing; Purging · CPC title

  • with temperature control (control of temperature G05D23/00; cryostats F17C3/08) · CPC title

  • for following a reaction, e.g. for determining photometrically a reaction rate (photometric cinetic analysis) · CPC title

  • Flow-through cuvettes (G01N21/09 takes precedence; handling fluid samples G01N1/10) · CPC title

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What does patent US2019329240A1 cover?
A conventional solution exchanging method in a next-generation sequencer needs a reagent amount four or more times greater than an in-flow cell flow passage volume in order to efficiently promote a chemical reaction by replacing a reagent A in the flow cell with a new reagent B. Thus, the reagent consumption amount increases, and the cost is high. Meanwhile, an analysis apparatus according to t…
Who is the assignee on this patent?
Hitachi High Tech Corp
What technology area does this patent fall under?
Primary CPC classification B01L3/567. Mapped technology areas include Operations & Transport.
When was this patent published?
Publication date Thu Oct 31 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).