Synthesis and application of A Nanomaterial for Removal of Patulin

Patent metadata

Field	Value
Publication number	US-2019329221-A1
Application number	US-201916508332-A
Country	US
Kind code	A1
Filing date	Jul 11, 2019
Priority date	Jul 25, 2018
Publication date	Oct 31, 2019
Grant date	—

Abstract

The present disclosure belongs to the technical field of analytical chemistry, in particular to synthesis and application of a nanomaterial for removal of patulin (Pat). The present disclosure adopts 2-Oxin as a substitute template, AM as a functional monomer, and synthetic Fe3O4@SiO2@CS-GO magnetic nanoparticles as a carrier, for preparing a magnetic MIP specific for Pat adsorption by surface imprinting. The addition of Fe3O4 makes the finally prepared molecular imprinted adsorbent material magnetic, thereby facilitating separation of a material from a matrix, eliminating complicated operation steps such as filtration and centrifugation, and facilitating recovery of materials.

First claim

What is claimed is:

1 . A synthesis method of nanomaterial for removal of patulin, comprising adopting 2-oxindole as a substitute template, acrylamide as a functional monomer, and Fe 3 O 4 @SiO 2 @CS-GO magnetic nanoparticles as a carrier, carrying out surface imprinting and preparing a magnetic molecular imprinted nanomaterial and obtaining the nanornaterial.

2 . The synthesis method according to claim 1 , wherein preparing the magnetic molecular imprinted nanomaterial comprises: preparation of Fe 3 O 4 magnetic cores; preparation of Fe 3 O 4 @SiO 2 nanoparticles; amination of the Fe 3 O 4 @SiO 2 nanoparticles and synthesis of the Fe 3 O 4 @SiO 2 nanoparticles; binding of GO carriers to the Fe 3 O 4 @SiO 2 @CS nanoparticles; and synthesis of Fe 3 O 4 @SiO 2 @CS-GO@MIP by surface imprinting.

3 . The synthesis method according to claim 2 , wherein preparation of the Fe 3 O 4 magnetic cores is as follows: dissolving FeCl 3 .6H 2 O in ethylene glycol, adding anhydrous sodium acetate and trisodium citrate, continuously stirring for 0.5 to 2 h, and allowing the reaction liquid to react at 160 to 250° C. for 2 to 5 h to obtain a Fe 3 O 4 mother liquid.

4 . The synthesis method according to claim 2 , wherein preparation of the Fe 3 O 4 @SiO 2 nanoparticles is as follows: adding Fe 3 O 4 magnetic liquid to anhydrous ethanol, adding ammonia water dropwise, reacting for 30 min, then, adding tetraethyl orthosilicate dropwise, and reacting for 2 to 5 hours to obtain a Fe 3 O 4 @SiO 2 core-shell nanoparticle dispersion.

5 . The synthesis method according to claim 2 , wherein amination of the Fe 3 O 4 @SiO 2 nanoparticles is as follows: adding 3-aminopropyltrimethoxysilane dropwise to the Fe 3 O 4 @SiO 2 dispersion and stirring for 1 to 3 h to obtain aminated Fe 3 O 4 @SiO 2 nanoparticles.

6 . The synthesis method according to claim 2 , wherein the synthesis of the Fe 3 O 4 @SiO 2 @CS nanoparticles comprises preparing a CS acetic acid solution as follows: placing CS powder in 2% acetic acid, and performing heating and stirring to dissolve the CS powder to obtain a CS acetic acid solution having a concentration of 8 to 15 g/L.

7 . The synthesis method according to claim 2 , wherein the preparation of Fe 3 O 4 @SiO 2 @CS-GO nanoparticle is as follows: mixing the aminated Fe 3 O 4 @SiO 2 dispersion with the CS acetic acid solution, performing stirring at 45 to 60° C. for 0.5 to 2 h, then adding a GO dispersion and continuing stirring for 0.5 to 2 h, finally, raising the temperature to 70 to 90° C., and dropwise adding a glutaraldehyde solution with a mass fraction of 5% to obtain the Fe 3 O 4 @SiO 2 @CS-GO nanoparticles.

8 . The synthesis method according to claim 2 , wherein the synthesis of Fe 3 O 4 @SiO 2 @CS-GO@MIP comprises preparation of a pre-assembly liquid of template molecules and functional monomers as follows: adding 2-oxindole and acrylamide to a mixed solution of acetonitrile and toluene, and performing stirring to obtain the pre-assembly liquid of template molecules and functional monomers; synthesis of Fe 3 O 4 @SiO 2 @CS-GO@MIP is as follows: adding the Fe 3 O 4 @SiO 2 @CS-GO dispersion modified with vinyl to the pre-assembly liquid for dispersion, then, sequentially adding a cross-linking agent ethylene glycol dimethacrylate and an initiator azobisisobutyronitrile, and reacting at 60° C. for 24 h to obtain magnetic nanoparticles.

9 . The nanomaterial prepared by the method according to claim 1 .

10 . The nanomaterial prepared by the method according to claim 2 .

11 . The nanomaterial prepared by the method according to claim 3 .

12 . The nanomaterial prepared by the method according to claim 4 .

13 . The nanomaterial prepared by the method according to claim 5 .

14 . The nanomaterial prepared by the method according to claim 6 .

15 . The nanomaterial prepared by the method according to claim 7 .

16 . The nanomaterial prepared by the method according to claim 8 .

Assignees

• Univ Jiangnan

Inventors

• Sun Xiulan
• Ji Jian
• Pi Fuwei
• Zhang Yinzhi
• Guo Wei
• Shan Xueqing

Classifications

• H01F1/0054

  Coated nanoparticles, e.g. nanoparticles coated with organic surfactant · CPC title

• B82Y25/00

  Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance · CPC title

• B01J20/28007

  with size in the range 1-100 nanometers, e.g. nanosized particles, nanofibers, nanotubes, nanowires or the like (carbon nanostructures B01J20/205) · CPC title

• B01J20/3212

  consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds · CPC title

• A23L2/80

  by adsorption · CPC title