Production method for n-(alpha-hydroxyethyl)formamide, production method for n-(alpha-alkoxyethyl)formamide, production device for n-(alpha-hydroxyethyl)formamide, and production device for n-(alpha-alkoxyethyl)formamide

Patent metadata

Field	Value
Publication number	US-2019241502-A1
Application number	US-201916387608-A
Country	US
Kind code	A1
Filing date	Apr 18, 2019
Priority date	Dec 8, 2016
Publication date	Aug 8, 2019
Grant date	—

Abstract

Provided is a production method for N-(α-hydroxyethyl) formamide, having a step (1) in which a basic catalyst stored in a catalyst supply device and formamide are mixed in a mixing tank; and a step (2) in which the formamide mixed with the basic catalyst is brought in contact with acetaldehyde and N-(α-hydroxyethyl) formamide is obtained. In step (1), at least part of the catalyst supply device is vibrated while the basic catalyst is supplied to the mixing tank.

First claim

1 . A method for producing N-(α-hydroxyethyl)formamide, comprising:
a step (1) of mixing a basic catalyst stored in a catalyst supply facility with formamide in a mixing tank;
a step (2) of bringing the formamide mixed with the basic catalyst into contact with acetaldehyde and obtaining N-(α-hydroxyethyl)formamide; wherein
the basic catalyst is supplied to the mixing tank while vibrating at least a part of the catalyst supply facility in the step (1).

2 . The method for producing N-(α-hydroxyethyl)formamide according to claim 1 , wherein the catalyst supply facility includes a catalyst storage tank for storing the basic catalyst, a powder feeder for supplying the basic catalyst, and a catalyst supply pipe for supplying the basic catalyst.

3 . The method for producing N-(α-hydroxyethyl)formamide according to claim 1 , wherein at least a part of the catalyst supply facility is vibrated by hammering.

4 . The method for producing N-(α-hydroxyethyl)formamide according to claim 1 , wherein an amount of the basic catalyst supplied from the catalyst supply facility to the mixing tank is 90% by mass or more with respect to a total mass of the basic catalyst stored in the catalyst supply facility in the step (1).

5 . The method for producing N-(α-hydroxyethyl)formamide according to claim 2 , wherein the basic catalyst is filled in the powder feeder and then supplied to the mixing tank in the step (1).

6 . The method for producing N-(α-hydroxyethyl)formamide according to claim 1 , wherein the formamide and the acetaldehyde are brought into contact with each other in a state in which the basic catalyst is dissolved in the step (2).

7 . N-(α-hydroxyethyl)formamide obtained by the production method according to claim 1 .

8 . A method for producing N-(α-alkoxyethyl)formamide, comprising:
a step (3) of bringing N-(α-hydroxyethyl)formamide obtained by the production method according to claim 1 into contact with an alcohol in presence of an acid catalyst and obtaining N-(α-alkoxyethyl)formamide.

9 . N-(α-alkoxyethyl)formamide obtained by the production method according to claim 8 .

10 . A device for producing N-(α-hydroxyethyl)formamide, comprising:
a catalyst supply facility for storing a basic catalyst;
a mixing tank for mixing the basic catalyst supplied from the catalyst supply facility with formamide;
a third tank for bringing the formamide which is mixed with the basic catalyst and supplied from the mixing tank into contact with acetaldehyde and obtaining N-(α-hydroxyethyl)formamide; and
a vibration imparting means for vibrating at least a part of the catalyst supply facility.

11 . The device for producing N-(α-hydroxyethyl)formamide according to claim 10 , wherein
the catalyst supply facility includes a catalyst storage tank for storing the basic catalyst, a powder feeder for supplying the basic catalyst, and a catalyst supply pipe for supplying the basic catalyst, and the powder feeder and the catalyst supply pipe are provided between the catalyst storage tank and the mixing tank.

12 . The device for producing N-(α-hydroxyethyl)formamide according to claim 11 , wherein the vibration imparting means is to vibrate the catalyst storage tank.

13 . The device for producing N-(α-hydroxyethyl)formamide according to claim 10 , wherein the vibration imparting means is hammering.

14 . A device for producing N-(α-alkoxyethyl)formamide, comprising:
a catalyst supply facility for storing a basic catalyst;
a mixing tank for mixing the basic catalyst supplied from the catalyst supply facility with formamide;
a third tank for bringing the formamide which is mixed with the basic catalyst and supplied from the mixing tank into contact with acetaldehyde and obtaining N-(α-hydroxyethyl)formamide;
a fourth tank for bringing the N-(α-hydroxyethyl)formamide supplied from the third tank into contact with an alcohol in presence of an acid catalyst and forming N-(α-alkoxyethyl)formamide; and
a vibration imparting means for vibrating at least a part of the catalyst supply facility.

15 . The device for producing N-(α-alkoxyethyl)formamide according to claim 14 , wherein
the catalyst supply facility includes a catalyst storage tank for storing the basic catalyst, a powder feeder for supplying the basic catalyst, and a catalyst supply pipe for supplying the basic catalyst, and the powder feeder and the catalyst supply pipe are provided between the catalyst storage tank and the mixing tank.

16 . The device for producing N-(α-alkoxyethyl)formamide according to claim 15 , wherein the vibration imparting means is to vibrate the catalyst storage tank.

17 . The device for producing N-(α-alkoxyethyl)formamide according to claim 14 , wherein the vibration imparting means is hammering.

Assignees

• Mitsubishi Chem Corp

Inventors

• Teramoto Kouji
• Nishimura Hitoshi

Classifications

• B01J37/04

  Mixing {(B01J37/0009, B01J37/0018 take precedence)} · CPC title

• B01J23/04

  Alkali metals · CPC title

• C07C231/12 Primary

  by reactions not involving the formation of carboxamide groups · CPC title

• C07C233/18

  having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton · CPC title

• C07B61/00

  Other general methods · CPC title