Devices for injection and dosing

Patent metadata

Field	Value
Publication number	US-2019201635-A1
Application number	US-201916299029-A
Country	US
Kind code	A1
Filing date	Mar 11, 2019
Priority date	Oct 1, 2014
Publication date	Jul 4, 2019
Grant date	—

Abstract

Skin can be treated by piercing skin with a plurality of needles of an injection device and ejecting a dose of fluid therethrough. The device can include a housing, a plunger disposed in the housing, a cartridge disposed in the housing, and one or more dosing chambers. The plurality of needles can be coupled to the housing and be in fluid communication with the cartridge. Advancement of the plunger can cause a dose of fluid to be ejected from the plurality of needles.

First claim

What is claimed is:

1 . A dermal filler injection device comprising:
a handpiece comprising:
a handpiece housing including an interior space for containing a cartridge having a plunger slidable within the cartridge; and
a trigger coupled to the housing; and
a head, in communication with the interior space, the head comprising a needle array housing assembly and a needle hub disposed within the needle array housing assembly and at least one needle secured to the needle hub; wherein the device is structured such that operation of the trigger initially causes the needle to be moved from a retracted position to an extended position; and wherein the head being manually separable from, and replaceable with respect to, the handpiece.

2 . The device of claim 1 , further comprising at least one dosing chamber in communication with the at least one needle.

3 . The device of claim 2 , wherein the at least one needle comprises a plurality of needles and the at least one dosing chamber comprises a plurality of dosing chambers, with each needle being in communication with a corresponding dosing chamber.

4 . The device of claim 2 , wherein the at least one dosing chamber is disposed in the handpiece.

5 . The device of claim 2 , wherein radial compression to the trigger causes distal advancement of a plunger relative to the cartridge disposed within the housing to cause a dose of composition contained in the at least one dosing chamber to be delivered.

6 . A dermal filler injection device comprising:
a housing including an interior space for containing a cartridge; a trigger coupled to the housing; a head in communication with the interior space and including plurality of dosing chambers, and a plurality of retractable needles coupled thereto; wherein the device is structured such that operation of the trigger initially causes the needle to be moved from a retracted position to an extended position and subsequently causes a dose of fluid contained in the dosing chamber to be ejected from the needle when the needle is in the extended position; the device further structured to cause retraction of the needles after the dosing; and a mechanism capable of filling each dosing chamber between subsequent injections.

7 . The device of claim 6 , wherein the plurality of needles comprises adjacent needles spaced apart by at least about 10 mm.

8 . The device of claim 6 , wherein the plurality of needles comprises adjacent needles spaced apart by less than 10 mm.

9 . The device of claim 6 , wherein the plurality of needles comprises adjacent needles spaced apart by about 3 mm to about 14 mm.

10 . The device of claim 6 , wherein the plurality of needles comprises linearly arranged needles.

11 . The device of claim 6 , wherein the plurality of needles comprises at least four linearly arranged needles.

12 . The device of claim 6 , wherein the plurality of needles comprises a two by two array of needles.

13 . The device of claim 6 , wherein the head further includes a plurality of conical or tapered projections, each needle having a tip protruding from an individual conical or tapered projection.

14 . The device of claim 13 , wherein each conical or tapered projection is spaced apart from each other conical or tapered projections so as to effect a preloading of skin when the head is applied to skin, to facilitate penetration of the needle tips into the skin.

15 . A method of treating skin comprising:
piercing skin with a plurality of needles of an injection device, the device comprising a housing, a plunger, a cartridge disposed within the housing, and a plurality of dosing chambers providing fluid communication between the cartridge and the plurality of needles to provide a dose of fluid to the plurality of needles; and actuating the plunger to distally advance the plunger relative to the cartridge to move the dose of fluid through the plurality of dosing chambers to be ejected from the plurality of dosing chambers into lumens of the plurality of needles.

16 . The method of claim 15 , wherein the injection device further comprises a trigger extending along a longitudinal axis of the housing and the plurality of needles are positioned adjacent to a distal end portion of the housing, and wherein the piercing comprises radially compressing the trigger.

17 . The method of claim 16 , wherein the radially compressing the trigger causes the device to move the plurality of needles from a retracted position to an extended position relative to the housing in which the needles extend longitudinally beyond the distal end portion of the housing to penetrate the skin.

18 . The method of claim 17 , wherein the plurality of dosing chambers are refilled with an additional dose of fluid upon release of the trigger.

19 . The method of claim 15 , further comprising contacting the skin with a distal end portion the injection device prior to piercing skin with the plurality of needles.

20 . The method of claim 15 , wherein actuating the plunger comprises manually actuating the plunger.

Assignees

• Allergan Inc

Inventors

• Franklin Ethan
• Stroumpoulis Dimitrios
• Dominguez Zachary
• Schwab Justin
• Mandaroux Bastien
• Kayda Edwin

Classifications

• A61M5/3287

  Accessories for bringing the needle into the body; Automatic needle insertion (A61M5/20, A61M5/31525 take precedence) · CPC title

• A61M5/321

  Means for protection against accidental injuries by used needles · CPC title

• A61M5/3298 Primary

  Needles arranged in parallel · CPC title

• A61M5/31593

  Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir · CPC title

• A61M37/0015

  by using microneedles · CPC title