Cyclic amine compound and pest control agent

Patent metadata

Field	Value
Publication number	US-2019191702-A1
Application number	US-201716098986-A
Country	US
Kind code	A1
Filing date	May 2, 2017
Priority date	May 9, 2016
Publication date	Jun 27, 2019
Grant date	—

Abstract

A compound represented by a formula (I), or a salt thereof:

wherein
Ar 1 is a substituted or unsubstituted C 6-10 aryl group, or the like; the number of X 1 groups that can be substituted on Ar 1 is 5 or less; X 1 is a halogeno group, a substituted or unsubstituted C 1-6 alkyl group, or the like; Z is a single bond, a sulfur atom, or an oxygen atom; A is a nitrogen atom or a carbon atom; X 2 is a halogeno group, a substituted or unsubstituted C 1-6 alkyl group, or the like; m is an integer of 0 to 2 when A is a nitrogen atom and is an integer of 0 to 3 when A is a carbon atom; R 1 to R 4 and R 6 to R 9 each independently represent a hydrogen atom, a substituted or unsubstituted C 1-6 alkyl group, or the like; R 5 is a hydrogen atom, a substituted or unsubstituted C 1-6 alkyl group, or the like; k represents the number of CR 6 R 7 moieties in a parenthesis and is 0 or 1; h represents the number of CR 3 R 4 moieties in a parenthesis and is 0 or 1; and Ar is a substituted or unsubstituted C 6-10 aryl group, or the like.

First claim

1 . A compound represented by a formula (I), or a salt thereof:

wherein
Ar 1 is a substituted or unsubstituted C 6-10 aryl group or a substituted or unsubstituted 5- to 6-membered heteroaryl group;
Z is a single bond, a sulfur atom, or an oxygen atom;
A is a nitrogen atom or a carbon atom;
X 2 represents a halogeno group, a substituted or unsubstituted C 1-6 alkyl group, a substituted or unsubstituted C 2-6 alkenyl group, a substituted or unsubstituted C 2-6 alkenyloxy group, a substituted or unsubstituted C 2-6 alkynyl group, a hydroxyl group, a substituted or unsubstituted C 1-6 alkoxy group, an amino group, a substituted or unsubstituted C 1-6 alkylamino group, a formyl group, a substituted or unsubstituted C 1-6 alkylcarbonyl group, a substituted or unsubstituted C 1-6 , alkylcarbonylamino group, a carboxyl group, a substituted or unsubstituted C 1-6 alkoxycarbonyl group, a carbamoyl group, a substituted or unsubstituted C 1-6 alkylaminocarbonyl group, a substituted or unsubstituted C 1-6 alkylaminocarbonyloxy group, a substituted or unsubstituted C 1-6 alkylcarbonyloxy group, a mercapto group, a substituted or unsubstituted C 1-6 alkylthio group, a substituted or unsubstituted C 1-6 alkylsulfinyl group, a substituted or unsubstituted C 1-6 alkylsulfonyl group, a substituted or unsubstituted C 1-6 alkoxysulfonyl group, a thiocarbamoyl group, a substituted or unsubstituted C 1-6 alkylaminothiocarbonyl group, an imino (substituted or unsubstituted C 1-6 alkylthio) methyl group, a substituted or unsubstituted C 1-6 alkylaminosulfonyl group, a substituted or unsubstituted C 3-8 cycloalkyl group, a substituted or unsubstituted C 6-10 aryl group, a substituted or unsubstituted heteroaryl group, a substituted or unsubstituted C 6-10 aryloxy group, a substituted or unsubstituted heteroaryloxy group, a nitro group, a cyano group, or a group represented by a foil mla: “R c O—N═CR d —” (wherein R c is a hydrogen atom, a substituted or unsubstituted C 1-6 alkyl group, or a substituted or unsubstituted C 1-6 alkylcarbonyl group, R d is a hydrogen atom, a substituted or unsubstituted C 1-6 alkyl group, or an amino group);
when there are 2 or more X 2 groups, X 2 groups may be the same as or different from each other;
m is an integer of 0 to 2 when A is a nitrogen atom and is an integer of 0 to 3 when A is a carbon atom;
R 1 to R 4 and R 6 to R 9 each independently represent a hydrogen atom, a substituted or unsubstituted C 1-6 alkyl group, a substituted or unsubstituted C 1-6 alkoxy group, a substituted or unsubstituted C 1-6 alkoxycarbonyl group, a hydroxyl group, or a halogeno group; R 1 and R 9 may form a C 2-6 alkylene group together, R 3 and R 6 may form a C 2-6 alkylene group together, and R 2 and R 3 may form a C 3-6 alkylene group together;
R 5 represents a hydrogen atom, a substituted or unsubstituted C 1-6 alkyl group, a substituted or unsubstituted C 1-6 alkoxy group, a substituted or unsubstituted C 1-6 alkylcarbonyl group, a substituted or unsubstituted C 1-6 alkoxycarbonyl group, a substituted or unsubstituted C 1-6 alkylaminocarbonyl group, a substituted or unsubstituted C 1-6 alkylcarbonyloxy group, a substituted or unsubstituted C 1-6 alkoxycarbonyloxy group, a substituted or unsubstituted phenyl group, a hydroxyl group, a halogeno group, or a cyano group; one of atoms constituting R 5 and one of atoms constituting Ar may be bonded to form a ring together with a carbon atom to which R 5 and Ar are bonded; and R 3 and R 3 may form a C 1-6 alkylenedioxy group together;
k represents the number of CR 6 R 7 moieties in a parenthesis and is 0 or 1;
h represents the number of CR 3 R 4 moieties in a parenthesis and is 0 or 1; and
Ar is a dihydrooxazolyl group, a substituted or unsubstituted C 6-10 aryl group or a substituted or unsubstituted heteroaryl group.

2 . The compound according to claim 1 represented by a formula (II), or a salt thereof:

wherein, Ar 1 , R 1 to R 4 , R 6 to R 9 , R 5 , and Ar are the same as those defined in the formula (I);
X 2a represents a hydrogen atom, or is the same as X 2 defined in the formula (I);
X 2b represents hydrogen atom, or is the same as X 2 defined in the formula (I); and
X 2b is the same as X 2 defined in the formula (I).

3 . The compound according to claim 1 , or a salt thereof, wherein a group that can be substituted on a C 6-10 aryl group or a 5- or 6-membered heteroaryl group represented by Ar 1 (a substitutable group is referred to as “X 1 ”, the number of the X 1 group is 5 or less, and when the number of the X 1 group is 2 or more, the X 1 groups may be the same as or different from each other, and two X 1 groups may form a divalent organic group together) is a halogeno group, a substituted or unsubstituted C 1-6 alkyl group, a substituted or unsubstituted C 2-6 alkenyl group, a substituted or unsubstituted C 2-6 alkenyloxy group, a substituted or unsubstituted C 2-6 alkynyl group, a hydroxyl group, a substituted or unsubstituted C 1-6 alkoxy group, an amino group, a substituted or unsubstituted C 1-6 alkylamino group, a formyl group, a substituted or unsubstituted C 1-6 alkylcarbonyl group, a substituted or unsubstituted C 1-6 alkylcarbonylamino group, a carboxyl group, a substituted or unsubstituted C 1-6 alkoxycarbonyl group, a carbamoyl group, a substituted or unsubstituted C 1-6 alkylaminocarbonyl group, a substituted or unsubstituted C 1-6 alkylaminocarbonyloxy group, a substituted or unsubstituted C 1-6 alkylcarbonyloxy group, a mercapto group, a substituted or unsubstituted C 1-6 alkylthio group, a substituted or unsubstituted C 1-6 alkylsulfinyl group, a substituted or unsubstituted C 1-6 alkylsulfonyl group, a substituted or unsubstituted C 1-6 alkoxysulfonyl group, a thiocarbamoyl group, a substituted or unsubstituted C 1-6 alkylaminothiocarbonyl group, a substituted or unsubstituted C 1-6 alkylaminosulfonyl group, a substituted or unsubstituted C 3-8 cycloalkyl group, a substituted or unsubstituted C 6-10 aryl group, a substituted or unsubstituted heteroaryl group, a substituted or unsubstituted C 6-10 aryloxy group, a substituted or unsubstituted heteroaryloxy group, a nitro group, a cyano group, a pentafluorosulfanyl group, or a group represented by a formula: “R a O—N═CR b —” (wherein R a is a hydrogen atom or a substituted or unsubstituted C 1-6 alkyl group, and le is a hydrogen atom or a substituted or unsubstituted C 1-6 alkyl group).

4 . The compound according to claim 1 represented by a formula (III), or a salt thereof:

wherein R 1 to R 4 , R 6 to R 9 , R 5 and Ar are the same as those defined in the formula (I);
X 1 represents a halogeno group, a substituted or unsubstituted C 1-6 alkyl group, a substituted or unsubstituted C 2-6 alkenyl group, a substituted or unsubstituted C 2-6 alkenyloxy group, a substituted or unsubstituted C 2-6 alkynyl group, a hydroxyl group, a substituted or unsubstituted C 1-6 alkoxy group, an amino group, a substituted or unsubstituted C 1-6 alkylamino group, a formyl group, a substituted or unsubstituted C 1-6 alkylcarbonyl group, a substituted or unsubstituted C 1-6 alkylcarbonylamino group, a carboxyl group, a substituted or unsubstituted C 1-6 alkoxycarbonyl group, a carbamoyl group, a substituted or unsubstituted C 1-6 alkylaminocarbonyl group, a substituted or unsubstituted C 1-6 alkylami

Assignees

• Nippon Soda Co

Inventors

• Iwata Jun
• NISHIO Fumiya
• Iwasa Takao
• Makino Satoshi
• Hirata Koichi

Classifications

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A61P33/00

  Antiparasitic agents · CPC title

• A01N43/82

  five-membered rings with three ring hetero atoms · CPC title

• C07D401/06

  linked by a carbon chain containing only aliphatic carbon atoms · CPC title

• A01N43/40

  six-membered rings · CPC title