Solid pharmaceutical tablet
US-2024226038-A9 · Jul 11, 2024 · US
Patch preparations with misuse prevention features
US2019175585A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2019175585-A1 |
| Application number | US-201916282215-A |
| Country | US |
| Kind code | A1 |
| Filing date | Feb 21, 2019 |
| Priority date | Mar 24, 2016 |
| Publication date | Jun 13, 2019 |
| Grant date | — |
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- Title
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- Abstract
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- Assignees and inventors
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Abstract
Official abstract text for this publication.
The present disclosure provides a patch preparation having features that prevent misuse. In some embodiments, a patch preparation containing a plaster on a support, wherein the plaster comprises a solvent that is a combination of ethyl acetate and n-heptane. The patch preparation can lose its adhesion after the plaster is exposed to air and at least some of the solvent has evaporated, or if the patch is removed from the skin. This feature prevent the used patch from being applied to the skin again, and can prevent misuse. A method of forming a patch preparation is also disclosed.
First claim
Opening claim text (preview).
What is claimed is: 1 . A patch preparation comprising a plaster disposed on a support, wherein the plaster comprises a solvent that is a combination of ethyl acetate and n-heptane, and the amount of the solvent is about 2% to 35% by weight of the plaster. 2 . The patch preparation of claim 1 , wherein the amount of solvent is about 5% to about 25% by weight of the plaster. 3 . The patch preparation of claim 1 , wherein the plaster further comprises a medicament. 4 . The patch preparation of claim 3 , wherein the medicament comprises one or more compound selected from the group consisting of morphine, codeine, fentanyl, oxycodone, and hydromorphone, and combinations thereof. 5 . The patch preparation of claim 3 , wherein the medicament comprises fentanyl or oxycodone. 6 . The patch preparation of claim 1 , wherein the plaster further comprises a base material. 7 . The patch preparation of claim 6 , wherein the base material comprises an elastic polymer. 8 . The patch preparation of claim 7 , wherein the elastic polymer is selected from the group consisting of an acrylic polymer, a rubber polymer, and a silicone-based polymer, and combinations thereof. 9 . The patch preparation of claim 1 , wherein the plaster further comprises one or more additives. 10 . The patch preparation of claim 1 , wherein the support is a solvent impermeable support. 11 . The patch preparation of claim 1 , wherein the support is a solvent permeable support.
Assignees
Inventors
Classifications
Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches · CPC title
manufacturing of adhesive dressings · CPC title
wound covering film layers without a fluid retention layer · CPC title
- A61K31/485Primary
Morphinan derivatives, e.g. morphine, codeine · CPC title
having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl · CPC title
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Frequently asked questions
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- What does patent US2019175585A1 cover?
- The present disclosure provides a patch preparation having features that prevent misuse. In some embodiments, a patch preparation containing a plaster on a support, wherein the plaster comprises a solvent that is a combination of ethyl acetate and n-heptane. The patch preparation can lose its adhesion after the plaster is exposed to air and at least some of the solvent has evaporated, or if the…
- Who is the assignee on this patent?
- Medrx Co Ltd
- What technology area does this patent fall under?
- Primary CPC classification A61K31/485. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Thu Jun 13 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).