Modular oscillatory flow plate reactor

Patent metadata

Field	Value
Publication number	US-2019111402-A1
Application number	US-201716092010-A
Country	US
Kind code	A1
Filing date	Apr 10, 2017
Priority date	Apr 8, 2016
Publication date	Apr 18, 2019
Grant date	—

Abstract

The present application relates to an improved apparatus for mixing intensification in multiphase systems, which can be operating in continuous or batch mode. In particular, it relates to a reactor, which can be assembled and disassembled easily for cleaning. The apparatus is based on oscillatory flow mixing (OFM) and comprises an oscillatory flow plate reactor (OFPR) provided with 2D Smooth Periodic Constrictions (2D-SPCs). The apparatus can be fully thermostatized and it is based on a modular system, in order to achieve most of the industrial application. The OFPR is suitable for multiphase applications such as screening reactions, bioprocess, gas-liquid absorption, liquid-liquid extraction, precipitation and crystallization. Regarding its size and geometry and the ability to operate at low flow rates, reagent requirements and waste are significantly reduced, as well as the manufacturing and operating costs, compared to the common reactor, such as continuous stirred tank reactor (CSTR) and the “conventional” OFR.

First claim

1 . An apparatus for mixing intensification comprising:
a plate reactor provided with a reactor vessel provided with smooth periodic constrictions (SPC), wherein the said smooth periodic constrictions (SPC) are present in two parallels faces of the rectangular or square cross section tube, characterizing the 2D smooth periodic constrictions; a mixing chamber; and oscillation means to oscillate the liquid or multiphase fluid within the reactor vessel.

2 . An apparatus according to claim 1 , wherein said plate reactor is built-up by stacking two or more slices resulting in tubes with rectangular or square cross section.

3 . An apparatus according to claim 1 , wherein said reactor vessel is provided with smooth edges.

4 . An apparatus according to claim 1 , wherein said reactor vessel is provided with at least two inlets or outlets.

5 . An apparatus according to claim 1 , wherein said reactor plate is assemblable and disassemblable.

6 . An apparatus according to claim 1 , wherein said reactor vessel is in the form of single plate reactor or at least two plate reactors, displaced in parallel, by stack up the plates.

7 . An apparatus according to claim 1 , wherein said reactor vessel is totally thermostatized.

8 . An apparatus according to claim 1 , wherein the said apparatus comprises a jacket.

9 . An apparatus according to claim 1 , wherein the mixing chamber is provided with at least two inlet or outlet ports.

10 . An apparatus according to claim 1 , wherein the distance (L) between consecutive convergent sections is 1 to 5 times the tube width (Dw) of the straight section.

11 . An apparatus according to claim 1 , wherein the convergent-divergent section length (L 1 ) of the reactor vessel is 0.5 to 3 times the tube width (Dw) of the straight section.

12 . An apparatus according to claim 1 , wherein the shortest tube width (dow) of the convergent
divergent section of the reactor vessel is 0.1 to 0.5 times the tube width (Dw) of the straight section.

13 . An apparatus according to claim 1 , wherein the radius of curvature (Re) of the sidewall of the convergent section of the reactor vessel is 0.1 to 0.5 times the tube width (Dw) of the straight section.

14 . An apparatus according to claim 1 , wherein the radius of curvature (Rd) of the sidewall of the divergent section of the reactor vessel is 0.1 to 0.5 times the tube width (Dw) of the straight section.

15 . An apparatus according to claim 1 , wherein the radius of curvature (Rt) at the convergent-divergent section centre of the reactor vessel is 0.1 to 0.5 times the tube width (Dw) of the straight section.

16 . An apparatus according to claim 1 , wherein the thickness perpendicular to xOy plane (m) is 0.2 to 3 times the tube width (Dw) of the straight section.

17 . An apparatus according to claim 1 , wherein the open area (a) is between 10% and 50%.

18 . Use of the apparatus disclosed in claim 1 in multiphase applications such as screening reactions, bioprocess, gas-liquid absorption, liquid-liquid extraction, precipitation and crystallization.

Assignees

• Univ Do Minho
• Univ Do Porto

Inventors

• Azevedo Ferreira Antonio Manuel
• Nogueira Da Rocha Femando Alberto
• Couto Teixeira Jose Antonio
• Castro Freitas Filipa Juliana Femandes

Classifications

• B01F2215/0431

  Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof · CPC title

• B01F5/0647

  Operations & Transport · mapped topic

• B01F5/0655 Primary

  Operations & Transport · mapped topic

• B01J19/2425

  in parallel · CPC title

• B01F11/0071

  Operations & Transport · mapped topic