Optical coherence tomography-based ophthalmic testing methods, devices and systems

Patent metadata

Field	Value
Publication number	US-2019090733-A1
Application number	US-201816184772-A
Country	US
Kind code	A1
Filing date	Nov 8, 2018
Priority date	Mar 27, 2008
Publication date	Mar 28, 2019
Grant date	—

Abstract

In accordance with one aspect of the present invention, an optical coherence tomography-based ophthalmic testing center system includes an optical coherence tomography instrument comprising an eyepiece for receiving at least one eye of a user or subject; a light source that outputs light that is directed through the eyepiece into the user's or subject's eye, an interferometer configured to produce optical interference using light reflected from the user's/subject's eye, an optical detector disposed so as to detect said optical interference; and a processing unit coupled to the detector. The ophthalmic testing center system can be configured to perform a multitude of self-administered functional and/or structural ophthalmic tests and output the test data

First claim

What is claimed is:

1 . An optical coherence tomography-based system comprising:
an optical coherence tomography device configured to obtain an optical coherence tomography scan of at least one first anterior eye region and at least one of a second intermediate or posterior eye region; a processor configured to analyze the optical coherence tomography scan or to generate an optical coherence tomography-based image based on the optical coherence tomography scan; and an output device configured to output on the output device a report based on the analysis of the optical coherence tomography scan or the optical coherence tomography-based image.

2 . The optical coherence tomography-based system of claim 1 , the optical coherence tomography-based image comprising the first and second regions.

3 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan is a plurality of B-scans.

4 . The optical coherence tomography-based system of claim 3 , wherein the plurality of B-scans are arranged in the direction of an axis, the axis is substantially parallel to an optical axis extending between the anterior eye region and the posterior eye region.

5 . The optical coherence tomography-based system of claim 1 , wherein the anterior eye region comprises a cornea.

6 . The optical coherence tomography-based system of claim 1 , wherein the anterior eye region comprises a iris.

7 . The optical coherence tomography-based system of claim 1 , wherein the anterior eye region comprises an angle.

8 . The optical coherence tomography-based system of claim 1 , wherein the anterior eye region comprises an anterior chamber.

9 . The optical coherence tomography-based system of claim 1 , wherein the anterior eye region comprises a lens.

10 . The optical coherence tomography-based system of claim 1 , wherein the anterior eye region comprises a tear film.

11 . The optical coherence tomography-based system of claim 1 , wherein the intermediate eye region comprises a vitreous.

12 . The optical coherence tomography-based system of claim 1 , wherein the posterior eye region comprises a choroid.

13 . The optical coherence tomography-based system of claim 1 , wherein the posterior eye region comprises an optic nerve.

14 . The optical coherence tomography-based system of claim 1 , wherein the posterior eye region comprises a retinal pigment epithelium.

15 . The optical coherence tomography-based system of claim 1 , wherein the posterior eye region comprises a retina.

16 . The optical coherence tomography-based system of claim 1 , wherein the posterior eye region comprises a posterior sclera.

17 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan further comprising at least one of any pre-corneal structure, retinal pigment epithelial, choroid, optic nerve, or a sclera.

18 . The optical coherence tomography-based system of claim 1 , the optical coherence tomography device configured to enable a user to self-administer the scan by using the device.

19 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan is a plurality of A-scans, each A-scan extending between the first region and the second region.

20 . The optical coherence tomography-based system of claim 19 , wherein the plurality of A-scans form a three-dimensional optical coherence tomography-based image.

21 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan is a plurality of B-scans.

22 . The optical coherence tomography-based system of claim 21 , wherein the B-scans are stacked in the direction of the axis

23 . The optical coherence tomography-based system of claim 22 , wherein the plurality of B-scans form a three-dimensional optical coherence tomography-based scan.

24 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan comprises at least a first optical coherence tomography scan and at least a second optical coherence tomography scan, wherein the first and second optical coherence tomography scans are of first and second eye regions.

25 . The optical coherence tomography-based system of claim 24 , wherein a gap exists between the eye regions.

26 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan is a Doppler optical coherence tomography scan.

27 . The optical coherence tomography-based system of claim 1 , wherein the processor is further configured to measure exophthalmometry measurements on the eye based on the optical coherence tomography scan.

28 . The optical coherence tomography-based system of claim 1 , wherein the processor is further configured to conduct a pupillometry test based on the optical coherence tomography scan.

29 . The optical coherence tomography-based system of claim 1 , wherein the processor is further configured to conduct a corneal topography test based on the optical coherence tomography scan.

30 . The optical coherence tomography-based system of claim 1 , wherein the processor is further configured to conduct a corneal pachymetry test based on the optical coherence tomography scan.

31 . The optical coherence tomography-based system of claim 1 , wherein the processor is further configured to conduct a gonioscopy test based on the optical coherence tomography scan.

32 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan comprises anterior chamber fluid or pathological tissue in the anterior chamber of the eye.

33 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan comprises anterior chamber angle tissue or pathological tissue in the anterior chamber angle of the eye.

34 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan comprises iris tissue or pathological tissue in the iris.

35 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan comprises lens tissue or pathological tissue in the lens

36 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan comprises lens capsule tissue or pathological tissue in the lens capsule.

37 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan includes vitreous tissue or pathological tissue in the vitreous.

38 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan includes retina tissue or pathological tissue in the retina.

39 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan includes choroid tissue or pathological tissue in the choroid.

40 . The optical coherence tomography-based system of claim 1 , wherein the optical coherence tomography scan includes contact lens material.

41 . The optical coherence tomography-

Assignees

• Doheny Eye Inst

Inventors

• Walsh Alexander C
• Updike Paul G
• Sadda Srinivas R

Classifications

• A61B5/0066

  Optical coherence imaging · CPC title

• A61B5/0073

  by tomography, i.e. reconstruction of 3D images from 2D projections (A61B5/0066 takes precedence) · CPC title

• A61B3/085

  for testing strabismus · CPC title

• A61B3/0091

  Fixation targets for viewing direction · CPC title

• A61B3/117

  for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes · CPC title