Liquid urease inhibitor formulations

Patent metadata

Field	Value
Publication number	US-2019039962-A1
Application number	US-201716075695-A
Country	US
Kind code	A1
Filing date	Feb 24, 2017
Priority date	Feb 24, 2016
Publication date	Feb 7, 2019
Grant date	—

Abstract

The present application generally relates to a method for the manufacture of a liquid composition essentially consisting of an organic solvent of the type glycol and a urease inhibitor of the type phosphoric triamide and products obtained therewith.

First claim

1 - 20 . (canceled)

21 . A method for the manufacture of a liquid composition essentially consisting of an organic solvent of the type glycol and a urease inhibitor of the type phosphoric triamide, and optionally a dye system, the method comprising the step of heating an amount of said organic solvent of the type glycol to a first temperature at least above 20° C. but below the melt temperature of said urease inhibitor of the type phosphoric triamide, and subsequently adding an amount of solid urease inhibitor of the type phosphoric triamide in said amount of organic solvent of the type glycol at a second temperature which is at most about equal to the first temperature, characterized in that the method comprises the step of
i) maintaining the liquid composition essentially consisting of an organic solvent of the type glycol and a urease inhibitor of the type phosphoric triamide, and optionally a dye system, at a third temperature, which temperature is greater than the first temperature, in the range of 60 to 80° C.

22 . The method according to claim 21 further comprising the step of subjecting the liquid composition essentially consisting of an organic solvent of the type glycol and a urease inhibitor of the type phosphoric triamide, and optionally a dye system, to an ultrasonic treatment.

23 . The method according to claim 21 , wherein the urease inhibitor of the type phosphoric triamide is a compound of formula (I):

wherein:
X is oxygen or sulphur;
R 1 is selected from the group consisting of alkyl, cycloalkenyl, aralkyl, aryl, alkenyl, alkynyl, and cycloalkyl; and
R 2 is selected from the group consisting of hydrogen, alkyl, cycloalkenyl, aralkyl, aryl, alkenyl, alkynyl, and cycloalkyl, or
R 1 and R 2 together may form an alkylene or alkenylene chain which may optionally include one or more heteroatoms of divalent oxygen, nitrogen or sulphur, completing a 4-, 5-, 6-, 7-, or 8-membered ring structure; and
R 3 , R 4 , R 5 and R 6 are individually selected from the group consisting of hydrogen and alkyl having 1 to 6 carbon atoms, and
R 1 , R 2 , R 3 , R 4 , R 5 and R 6 , when not hydrogen, may each be optionally substituted with one or more selected from the group consisting of trihalomethyl, naphtoxy, alkyl, halogen, arylmercapto, phenoxy, phenyl, nitro, cyano, amino, alkylamino, dialkylamino, alkoxy, mercapto, alkylmercapto, alkylcarbonyl, arylamino, arylcarbonyl, alkoxycarbonyl, carboxy, diarylamino, and carbonamide.

24 . The method according to claim 21 , wherein the organic solvent of the type glycol is a compound of formula (II)

wherein
R 7 is hydrogen or alkyl;
R 8 is hydrogen or alkyl
R 9 is hydrogen, ═O, or alkyl;
R 10 is hydrogen, alkyl, or acyl; and
m is 1 to 4;
wherein R 7 and R 8 , or R 7 and R 10 together may form a ring comprising one or more oxygen atoms;
preferably wherein the organic solvent of the type glycol is a compound of formula (III)

wherein:
R 7 is hydrogen or alkyl;
R 8 is hydrogen or alkyl; and
m is 1 to 4.

25 . The method according to claim 21 , wherein the urease inhibitor is N-(n-butyl) thiophosphoric triamide (nBTPT) and/or wherein the organic solvent is propylene glycol, diethylene glycol monomethyl ether (DEGMME), diethylene glycol monobutyl ether (DEGMBE), or combinations thereof.

26 . The method according to claim 21 , wherein the amount of said urease inhibitor of the type phosphoric triamide ranges from 1 to 45 weight %, relative to the total weight of said liquid composition and/or wherein the amount of said organic solvent of the type glycol ranges between 55 and 99 weight %, relative to the total weight of said liquid composition.

27 . The method according to claim 21 , wherein the first temperature is in the range of 20 to 60° C. and/or wherein the second temperature is in the range of 20 to 60° C.

28 . The method according to claim 21 , wherein the liquid composition essentially consisting of an organic solvent of the type glycol and a urease inhibitor of the type phosphoric triamide, and optionally a dye system, is kept at a third temperature for a period of a few minutes to 4 hours.

29 . The method according to claim 21 , wherein the liquid composition essentially consisting of an organic solvent of the type glycol and a urease inhibitor of the type phosphoric triamide, and optionally a dye system, is ultrasonically treated for a period of a few minutes to 4 hours.

30 . The method according to claim 21 further comprising a step wherein an amount of a dye system is added to the liquid composition essentially consisting of an organic solvent of the type glycol and a urease inhibitor of the type phosphoric triamide at a fourth temperature, preferably at least 20° C.

31 . The method according to claim 30 , wherein the amount of said dye system ranges between 0 and 1.0 weight %.

32 . The method according to claim 21 , comprising the steps of:
heating up an amount of propylene glycol to 35 to 50° C.; adding 10 to 25 weight %, relative to the total weight of said liquid composition, of N-(n-butyl) thiophosphoric triamide (nBTPT) in said propylene glycol; applying an ultrasonic treatment for 15 minutes; maintaining said liquid composition essentially consisting of propylene glycol and nBTPT at 60 to 80° C.; and optionally, adding 0.25 weight %, relative to the total weight of said liquid composition, of a dye system to said liquid composition essentially consisting of propylene glycol and nBTPT at least at 20° C.

33 . A liquid composition essentially consisting of an organic solvent of the type glycol and a urease inhibitor of the type phosphoric triamide, and optionally a dye system, having a crystallization temperature of the urease inhibitor of the type phosphoric triamide in said organic solvent of the type glycol of less than 0° C.

34 . A liquid composition according to claim 33 , having a crystallization temperature of the urease inhibitor of the type phosphoric triamide in said organic solvent of the type glycol of less than −2° C., preferably less than −4° C., more preferably less than −6° C., most preferably less than −8° C.

35 . A liquid composition according to claim 33 , essentially consisting of propylene glycol (PG), in particular propaan-1,2-diol, as a solvent and 10 to 20 weight % of N-(n-butyl) thiophosphoric triamide (nBTPT), in particular 15 to 18 weight %, more in particular about 17.5 weight %, relative to the total weight of the liquid solution.

36 . A liquid composition according to claim 33 , essentially consisting of diethylene glycol monomethyl ether (DEGMME), diethylene glycol monobutyl ether (DEGMBE), or combinations thereof, optionally further including propylene glycol (PG), as a solvent and 10 to 40 weight % of N-(n-butyl) thiophosphoric triamide (nBTPT), in particular 15 to 30 weight %, more in particular about 25 weight %, relative to the total weight of the liquid solution.

37 . A solid particulate urea-based composition, comprising a solid particulate urea-based compound and the liquid composition according to claim 33 , wherein the liquid composition forms at least partially a coating on at least

Assignees

• Yara Int Asa

Inventors

• Colpaert Filip
• Ledoux Francois
• Van Belzen Ruud

Classifications

• C05G3/90

  for affecting the nitrification of ammonium compounds or urea in the soil · CPC title

• C05C9/005 Primary

  Post-treatment · CPC title

• C05G3/08

  Chemistry & Metallurgy · mapped topic

• C05G3/0064

  Chemistry & Metallurgy · mapped topic

• C05G5/30

  Layered or coated, e.g. dust-preventing coatings · CPC title