Delivery Device Including Reactive Material For Programmable Discrete Delivery Of A Substance
US-2017119960-A1 · May 4, 2017 · US
US2019024823A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2019024823-A1 |
| Application number | US-201715656126-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jul 21, 2017 |
| Priority date | Jul 21, 2017 |
| Publication date | Jan 24, 2019 |
| Grant date | — |
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Embodiments of the present invention are directed to a liquid delivery apparatus. A non-limiting example of the apparatus includes a substrate including a cavity formed in a surface of the substrate. The apparatus can also include a membrane disposed on the surface of the substrate covering an opening of the cavity. The apparatus can also include a hydrophobic layer disposed on the membrane. The apparatus can also include a seal disposed between the membrane and the substrate, wherein the seal surrounds the opening of the cavity. The apparatus can also include an electrode layer coupled to the membrane.
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What is claimed is: 1 . A liquid delivery apparatus comprising: a first substrate comprising a reservoir formed in the first substrate; a membrane disposed on the surface of the first substrate covering an opening of the reservoir; a second substrate bonded to the first substrate, wherein the second substrate comprises a reservoir seal; a hydrophobic layer disposed on an inside surface of the membrane; and electrodes in electrical contact with the membrane. 2 . The apparatus of claim 1 , wherein at least a portion of the membrane comprises a metal film. 3 . The apparatus of claim 1 , wherein at least a portion of the membrane comprises an electrically-insulating film. 4 . The apparatus of claim 1 , wherein the reservoir seal comprises indium. 5 . The apparatus of claim 1 further comprising a hydrophilic layer disposed on a surface of the reservoir opposite the membrane. 6 . The apparatus of claim 1 , wherein the hydrophobic layer comprises a fluorocarbon film. 7 . The apparatus of claim 1 further comprising a sensor. 8 . The apparatus of claim 1 , wherein the hydrophobic layer comprises a porous electrodeposited metal film. 9 . The apparatus of claim 1 , wherein the hydrophobic layer has a thickness of about 5 Angstroms (Å) to about 1 micron. 10 . The apparatus of claim 1 further comprising a liquid in the reservoir. 11 . The apparatus of claim 10 , wherein the liquid comprises an active pharmaceutical agent. 12 . The apparatus of claim 9 , wherein the liquid comprises a microbattery electrolyte. 13 . The apparatus of claim 1 , wherein the hydrophobic layer lines a portion of the cavity. 14 . A liquid delivery apparatus comprising: a substrate comprising a cavity formed in a surface of the substrate; a membrane connected to a hinged structure; a hydrophobic layer disposed on the membrane; and a seal disposed between the membrane and the substrate, wherein the seal surrounds the opening of the cavity. 15 . The apparatus of claim 14 , wherein at least a portion of the membrane comprises a metal film. 16 . The apparatus of claim 14 further comprising a hydrophilic layer disposed on a surface of the cavity opposite the membrane. 17 . The apparatus of claim 14 , wherein the hydrophobic layer comprises a material selected from the group consisting of fluorocarbon films, micro-structured polymers, carbon nanotubes, electrodeposited metal films, oxides, oxide composites, and patterned films. 18 . The apparatus of claim 14 , wherein the hydrophobic layer has a thickness of about 1 Angstrom (Å) to about 500 nanometers (nm). 19 . The apparatus of claim 14 further comprising a liquid in the cavity. 20 . The apparatus of claim 19 , wherein the liquid comprises an active pharmaceutical agent. 21 . The apparatus of claim 19 , wherein the liquid comprises a microbattery electrolyte. 22 . The apparatus of claim 19 , wherein the hydrophobic layer lines a portion of the cavity. 23 . An electronic delivery device comprising: a dispensing array comprising a plurality of reservoirs, wherein the dispensing array comprises a cavity, a membrane covering an opening of the cavity, and a hydrophobic layer disposed on the membrane; a microprocessor in communication with the dispensing array; and a wireless receiver in communication with the microprocessor. 24 . A method of delivering liquids comprising: forming a hydrophobic liner on a release membrane covering a delivery structure reservoir; depositing a liquid in the reservoir; sealing the reservoir with a hydrophilic layer; and providing an electric current to the release membrane to dispense the liquid. 25 . A computer program product for delivery of liquids comprising: a computer readable storage medium having program instructions embodied therewith, wherein the instructions are executable by a processor to cause the processor to perform a method comprising: receiving a signal from a sensor concerning a local environmental condition; sending, based at least in part upon the signal, an electric current to a release membrane lined with a hydrophobic liner, wherein the release membrane covers a delivery structure reservoir; and rupturing the membrane with the electric current.
electrical or electronic {(A61M5/16804, A61M5/16831 take precedence)} · CPC title
Other apparatus for introducing media into the body (for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30); Percutany, i.e. introducing medicines into the body by diffusion through the skin (salt baths A61H33/04) · CPC title
Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology · CPC title
using feedback of body parameters, e.g. blood-sugar, pressure (measurement of body parameters A61B5/00) · CPC title
Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time (artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50) · CPC title
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