Compositions for spore removal

Patent metadata

Field	Value
Publication number	US-2018360728-A1
Application number	US-201615736853-A
Country	US
Kind code	A1
Filing date	Jun 27, 2016
Priority date	Jul 1, 2015
Publication date	Dec 20, 2018
Grant date	—

Abstract

Disclosed herein are compositions that include at least about 85 wt % of a hydroalcoholic solution that includes at least about 1 wt % water; and about 30 to about 85 wt % of at least one C1 to C4 alkyl alcohol based on the total weight of the hydroalcoholic solution; and acrylate copolymer particles dispersed in the hydroalcoholic solution, the acrylate copolymers particles being the reaction product of a reaction mixture, the reaction mixture including monomers, the monomers including from about 5 wt % to about 50 wt % of at least one high Tg monomer; and from about 20 w% to about 80 wt % of at least one low Tg monomer where the wt % of the low and high Tg monomers are with respect to the total weight of the monomers in the reaction mixture, wherein the particles have a number average diameter of at least about 100 nm.

First claim

1 . A composition comprising:
a) at least about 85 wt % of a hydroalcoholic solution, the hydroalcoholic solution comprising:
at least about 1 wt % water based on the total weight of the hydroalcoholic solution; and
about 30 wt % to about 85 wt % of at least one C 1 to C 4 alkyl alcohol based on the total weight of the hydroalcoholic solution; and
b) acrylate copolymer particles dispersed in the hydroalcoholic solution, the acrylate copolymer particles comprising the reaction product of a reaction mixture, the reaction mixture comprising monomers, the monomers comprising:
from about 5 wt % to about 50 wt % of at least one high Tg monomer where the wt % of the high Tg monomer is with respect to the total weight of the monomers in the reaction mixture; and
from about 20 wt % to about 80 wt % of at least one low Tg monomer where the wt % of the low Tg monomer is with respect to the total weight of the monomers in the reaction mixture,
wherein the particles have a number average diameter of at least about 100 nm.

2 . The composition according to claim 1 , wherein there is more of the at least one low Tg monomer than there is of the at least one high Tg monomer by weight in the reaction mixture.

3 . The composition according to claim 1 , wherein there is not greater than about 5 wt % of the acrylate copolymer particles in the composition based on the total weight of the composition.

4 . The composition according to claim 1 , wherein there is from about 0.5 wt % to about 4 wt % of the acrylate copolymer particles in the composition based on the total weight of the composition.

5 . The composition according to claim 1 , wherein there is at least about 60 wt % of the at least one alcohol in the composition based on the total weight of the composition.

6 . The composition according to claim 1 , wherein the acrylate copolymer is the reaction product of about 20 wt % to about 40 wt % of the at least one high Tg monomer based on the total weight of the monomers in the reaction mixture.

7 . The composition according to claim 1 , wherein the acrylate copolymer is the reaction product of about 60 wt % to about 80 wt % of the at least one low Tg monomer based on the total weight of the monomers in the reaction mixture.

8 . The composition according to claim 1 , wherein the at least one low Tg monomer has an alkyl carbon chain length from about 4 to about 10.

9 . The composition according to claim 1 , wherein the at least one low Tg monomer has a Tg from about −20° C. to about −60° C.

10 . The composition according to claim 1 , wherein the at least one high Tg monomer has a carbon chain length from about 1 to about 3.

11 . The composition according to claim 1 , wherein the at least one high Tg monomer has a Tg from about 40° C. to about 150° C.

12 . The composition according to claim 1 , wherein the acrylate copolymer particles have a number average diameter from about 200 to about 500 nm.

13 . The composition according to claim 1 , wherein the at least one C 1 to C 4 alcohol is selected from ethanol, n-propanol, 2-propanol or mixtures thereof.

14 . The composition according to claim 1 further comprising an antimicrobial agent in addition to the alcohol.

15 . The composition according to claim 14 , wherein the antimicrobial agent is cationic.

16 . A composition comprising:
at least about 1 wt % water based on the total weight of the composition; from about 30 wt % to about 98 wt % of at least one C 1 to C 4 alkyl alcohol based on the total weight of the composition; and not greater than about 5 wt % acrylate copolymer particles based on the total weight of the composition, where the acrylate copolymer particles are dispersed in the water and alcohol, the acrylate copolymer particles comprising the reaction product of a reaction mixture, the reaction mixture comprising monomers, the monomers comprising:
from about 5 wt % to about 50 wt % of at least one high Tg monomer, where the wt % of the at least one high Tg monomer is with respect to the total weight of the monomers in the reaction mixture; and
from about 20 wt % to about 80 wt % of at least one low Tg monomer where the wt % of the at least one low Tg monomer is with respect to the total weight of the monomers in the reaction mixture and
wherein the particles have a number average diameter of at least 100 nm.

17 . A method of dislodging at least one spore from a surface, the method comprising:
a) contacting the surface with a composition, the composition comprising: at least about 60 wt % of at least one C 1 to C 4 alkyl alcohol based on the total weight of the composition; and
acrylate copolymer particles dispersed in the alcohol; and
b) subjecting the surface in contact with the composition to mechanical action.

18 . The method of claim 17 , wherein at least some of the mechanical action is occurring at the same time that some of the composition is present on the surface.

19 . The method according to claim 17 , wherein the step of contacting the surface with the composition comprises applying the composition to skin.

20 .- 32 . (canceled)

33 . A method of removing at least one spore from a surface, the method comprising:
contacting the surface with a composition, the composition comprising: at least about 85 wt % of a hydroalcoholic solution based on the total weight of the composition, the hydroalcoholic solution comprising:
at least about 1 wt % water based on the weight of the hydroalcoholic solution, and
about 30 wt % to about 95 wt % of at least one C 1 to C 4 alkyl alcohol based on the total weight of the hydroalcoholic solution; and
acrylate copolymer particles dispersed in the hydroalcoholic solution, the acrylate copolymer particles comprising the reaction product of a reaction mixture, the reaction mixture comprising monomers, the monomers comprising:
from about 5 wt % to about 50 wt % of at least one high Tg monomer where the wt % of the at least one high Tg monomer is with respect to the total weight of the monomers in the reaction mixture; and
from about 20 w% to about 80 wt % of at least one low Tg monomer where the wt % of the at least one low Tg monomer is with respect to the total weight of the monomers in the reaction mixture,
wherein the acrylate copolymer particles have an average diameter of at least about 100 nm.

34 .- 39 . (canceled)

Assignees

• 3M Innovative Properties Co

Inventors

• Parthasarathy Ranjani V
• Kumar Ramesh C
• Scholz Matthew T
• Swanson Steven P
• Satterwhite Erin A

Classifications

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A61K8/0241

  Containing particulates characterized by their shape and/or structure (see also A61K8/04, A61K8/11, and A61K8/14, further aspects are classified in A61K2800/40 and subcodes) · CPC title

• A61P31/04

  Antibacterial agents · CPC title

• A61L2/18

  Liquid substances · CPC title

• A01N43/40

  six-membered rings · CPC title