Processing biomass
US-2015353974-A1 · Dec 10, 2015 · US
Method to produce L-methionine by a fermentative production
US2018355390A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2018355390-A1 |
| Application number | US-201615774267-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jan 8, 2016 |
| Priority date | Jan 8, 2016 |
| Publication date | Dec 13, 2018 |
| Grant date | — |
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Abstract
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A method can produce L-methionine and/or a derivative of L-methionine. The method includes: culturing a microorganism for the fermentative production of L-methionine and/or a L-methionine derivative in a culture medium comprising a carbon source, a sulphur source and nitrogen source to produce L-methionine and/or a L-methionine derivative; recovering the L-methionine or L-methionine derivative obtained from the culturing; adding an alcohol solvent or acetonitrile to the L-methionine and/or the L-methionine derivative thereof containing fraction obtained from the recovering to precipitate the L-methionine and/or L-methionine derivative; and recovering L-methionine and/or L-methionine derivative.
First claim
Opening claim text (preview).
1 : A method for the a fermentative production of L-methionine and/or a derivative thereof, the method comprising: i) culturing a microorganism for the fermentative production of L-methionine and/or a derivative thereof in a culture medium comprising a carbon source, a sulphur source and nitrogen source to produce L-methionine and/or a derivative thereof; ii) recovering the L-methionine and/or a derivative thereof obtained from said i) culturing; iii) adding an alcohol solvent or acetonitrile to the L-methionine and/or a derivative thereof containing fraction obtained from said ii) recovering to precipitate the L-methionine and/or a derivative thereof; and iv) recovering L-methionine and/or a derivative thereof. 2 : The method according to claim 1 , wherein the microorganism of said i) culturing is the sole microorganism. 3 : The method according to claim 1 , which does not comprise any enzymatic processing of an L-methionine precursor. 4 : The method according to claim 1 , wherein said ii) recovering comprises a clarification of the fermentation medium, optionally followed by a crystallization of L-methionine and/or a derivative thereof. 5 : The method according to claim 1 , wherein the alcohol solvent of said iii) adding is at least one member selected from the group consisting of ethanol and isopropanol. 6 : The method according to claim 1 , wherein the alcohol solvent of said iii) adding is ethanol. 7 : The method according to claim 1 , wherein, in said iii) adding, ratio solvent/(methionine containing fraction+solvent) is from 50 to 80% by weight. 8 : The method according to claim 1 , wherein in said iii) adding, a residual solubility of L-methionine in a supernatant after said iii) adding is from 5 to 6 g·L −1 at room temperature. 9 : The method according to claim 1 , wherein, in said iii) adding, ratio solvent/(methionine containing fraction+solvent) is from 65 to 78% by weight.
Assignees
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Classifications
with amino groups bound to the carbon skeleton · CPC title
- C12P13/12Primary
Methionine; Cysteine; Cystine · CPC title
Separation; Purification · CPC title
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- What does patent US2018355390A1 cover?
- A method can produce L-methionine and/or a derivative of L-methionine. The method includes: culturing a microorganism for the fermentative production of L-methionine and/or a L-methionine derivative in a culture medium comprising a carbon source, a sulphur source and nitrogen source to produce L-methionine and/or a L-methionine derivative; recovering the L-methionine or L-methionine derivative …
- Who is the assignee on this patent?
- Evonik Degussa Gmbh
- What technology area does this patent fall under?
- Primary CPC classification C12P13/12. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Thu Dec 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).