Biosensor and method for forming the same and glucose control system, method for forming the glucose system, and method for controlling glucose thereby

Patent metadata

Field	Value
Publication number	US-2018353684-A1
Application number	US-201615735563-A
Country	US
Kind code	A1
Filing date	Jun 3, 2016
Priority date	Jun 12, 2015
Publication date	Dec 13, 2018
Grant date	—

Abstract

The glucose control system comprises a sensor unit comprising a glucose sensor, a glucose regulation unit regulating glucose concentration in a body of a user and a control unit controlling the sensor unit and the glucose regulation unit. The method for forming a glucose control system comprises forming a sensor unit comprising a glucose sensor, forming a glucose regulation unit and packaging the sensor unit and the glucose regulation unit.

First claim

1 - 21 . (canceled)

22 . A glucose control system comprising:
a sensor unit comprising a glucose sensor; a glucose regulation unit regulating glucose concentration in a body of a user; and a control unit controlling the sensor unit and the glucose regulation unit.

23 . The glucose control system of claim 22 , wherein the sensor unit further comprises at least one selected from a humidity sensor, a pH sensor and a strain gauge.

24 . The glucose control system of claim 23 , wherein the control unit receives signals from the glucose sensor to measure glucose concentration in sweat of the user, receives signals from the pH sensor to measure pH value, and amends the measured glucose concentration based on the pH value.

25 . The glucose control system of claim 24 , wherein the control unit receives signals from the humidity sensor to measure humidity, receives signals from the strain gauge to measure strain, and amends the measured glucose concentration based on the pH value, the humidity and the strain.

26 . The glucose control system of claim 24 , wherein the control unit receives signals from the humidity sensor to measure humidity, and receives signals from the glucose sensor to measure the glucose concentration in sweat of the user when the humidity is equal to or more than a predetermined value.

27 . The glucose control system of claim 24 , wherein the control unit diagnoses a blood sugar state in the body of the user based on the amended glucose concentration.

28 . The glucose control system of claim 27 , wherein the control unit controls the glucose regulation unit in order to inject a glucose regulation drug into the user based on the diagnosed blood sugar state in the body of the user.

29 . The glucose control system of claim 23 , wherein the control unit receives signals from the strain gauge to measure strain, and diagnoses a blood sugar state in the body of the user as a low blood sugar state based on the strain.

30 . The glucose control system of claim 22 , wherein the glucose regulation unit comprises a drug delivery part that comprises a fine needle comprising a glucose regulation drug and a heating part that is disposed on the drug delivery part and heats the drug delivery part to increase a temperature of the drug delivery part, a surface of the drug delivery part is coated with a phase change material whose phase is changed at critical temperature or more, and the glucose regulation drug is released from the fine needle by heating the heating part.

31 . The glucose control system of claim 30 , wherein the drug delivery part injects the glucose regulation drug through the user's skin by the fine needle, and the glucose regulation drug comprises blood sugar depressing agents.

32 . The glucose control system of claim 30 , wherein the heating part comprises a first heating part, a second heating part adjacent to the first heating part, and a temperature sensor that is disposed between the first and second heating parts and measures temperature of the first and second heating parts, and further wherein the control unit controls temperature of the first and second heating parts when the temperature measured by the temperature sensor is equal to or more than a predetermined temperature.

33 . The glucose control system of claim 30 , wherein the heating part comprises multiply-bent patterns.

34 . The glucose control system of claim 22 , wherein the sensor unit comprises a sensing unit, a bridge unit connected to the sensing unit and an electrode unit connected to the bridge unit, and the sensing unit comprises a graphene layer.

35 . The glucose control system of claim 34 , wherein the graphene layer comprises a doped conductive substance, and the conductive substance comprises at least one selected from metal nanoparticles and metal nanowires.

36 . The glucose control system of claim 34 , wherein the sensing unit further comprises a conductive electrode layer disposed under the graphene layer and a reaction layer disposed on the graphene layer, the conductive electrode layer comprises net patterns or mesh patterns, and the reaction layer is formed of different substances depending on a type of the sensing unit.

37 . The glucose control system of claim 34 , wherein the bridge unit has a multiply-bent shape.

38 . The glucose control system of claim 22 , further comprising a network transmission and reception unit that sends the blood sugar state in the body of the user diagnosed by the control unit to a user terminal interacting with the glucose control system.

39 - 49 . (canceled)

Assignees

• Seoul Nat Univ R&Db Foundation
• Inst Basic Science

Inventors

• Kim Daehyeong
• Hyeon Taeghwan
• Choi Seunghong
• Lee Hyunjae
• Choi Taekyu

Classifications

• A61B5/4266

  sweat secretion · CPC title

• G01N33/84

  involving inorganic compounds or pH · CPC title

• G01N33/66

  involving blood sugars, e.g. galactose · CPC title

• A61M5/1723 Primary

  using feedback of body parameters, e.g. blood-sugar, pressure (measurement of body parameters A61B5/00) · CPC title

• G01N27/3271

  Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood (amperometry per se G01N27/49; aspects concerning the enzyme reagent C12Q1/001) · CPC title