Treatment of addiction and impulse-control disorders using PDE7 inhibitors
US-9220715-B2 · Dec 29, 2015 · US
US2018303838A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2018303838-A1 |
| Application number | US-201715839685-A |
| Country | US |
| Kind code | A1 |
| Filing date | Dec 12, 2017 |
| Priority date | Mar 15, 2013 |
| Publication date | Oct 25, 2018 |
| Grant date | — |
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This invention is in the area of improved compounds and methods for transiently protecting healthy cells, and in particular hematopoietic stem and progenitor cells (HSPC), from the damage associated with ionizing radiation (IR) exposure using selective radioprotectants.
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1 . A pharmaceutical composition comprising an effective amount of a compound having the formula: wherein R is C(X) 2 , wherein the two X groups together form an alkyl bridge to form a spiro compound; or its pharmaceutically acceptable salt thereof; in a pharmaceutically acceptable carrier.
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