Transient protection of hematopoietic stem and progenitor cells against ionizing radiation

US2018303838A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2018303838-A1
Application numberUS-201715839685-A
CountryUS
Kind codeA1
Filing dateDec 12, 2017
Priority dateMar 15, 2013
Publication dateOct 25, 2018
Grant date

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

This invention is in the area of improved compounds and methods for transiently protecting healthy cells, and in particular hematopoietic stem and progenitor cells (HSPC), from the damage associated with ionizing radiation (IR) exposure using selective radioprotectants.

First claim

Opening claim text (preview).

1 . A pharmaceutical composition comprising an effective amount of a compound having the formula: wherein R is C(X) 2 , wherein the two X groups together form an alkyl bridge to form a spiro compound; or its pharmaceutically acceptable salt thereof; in a pharmaceutically acceptable carrier.

Assignees

Inventors

Classifications

  • ortho- or peri-condensed with heterocyclic rings · CPC title

  • Growth factors; Growth regulators · CPC title

  • IL-12 · CPC title

  • Shielding, protecting against radiation · CPC title

  • Colony stimulating factors [CSF] · CPC title

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Frequently asked questions

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What does patent US2018303838A1 cover?
This invention is in the area of improved compounds and methods for transiently protecting healthy cells, and in particular hematopoietic stem and progenitor cells (HSPC), from the damage associated with ionizing radiation (IR) exposure using selective radioprotectants.
Who is the assignee on this patent?
G1 Therapeutics Inc
What technology area does this patent fall under?
Primary CPC classification A61K31/527. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Thu Oct 25 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).