Method for preparing high-water-content emulsion gel using oil gelling agent

Patent metadata

Field	Value
Publication number	US-2018280296-A1
Application number	US-201615755266-A
Country	US
Kind code	A1
Filing date	Aug 25, 2016
Priority date	Aug 25, 2015
Publication date	Oct 4, 2018
Grant date	—

Abstract

A stable high-water-content W/O-type emulsion gel comprising: a gelator composed of a compound of Formula (1) or (2) below

(wherein, R 1 and R 3 are each independently a linear or branched alkyl group having a carbon atom number of 1 to 20, a cyclic alkyl group having a carbon atom number of 3 to 20, or a linear or branched alkenyl group having a carbon atom number of 2 to 20, n is an integer of 0 or 1 to 4, R 2 is a hydrogen atom, a linear or branched alkyl group having a carbon atom number of 1 to 10, or an aryl group optionally having a substituent, and R 4 and R 5 are a hydroxyl group); a surfactant; and a mixed solvent of a hydrophobic organic solvent and water, wherein the content of the gelator is 0.1-20% by mass with respect to the mass of the mixed solvent.

First claim

1 . A W/O-type emulsion gel comprising:
a gelator composed of a compound of Formula (1) or (2) below

(wherein, R 1 and R 3 are each independently a linear or branched alkyl group having a carbon atom number of 1 to 20, a cyclic alkyl group having a carbon atom number of 3 to 20, or a linear or branched alkenyl group having a carbon atom number of 2 to 20, n is an integer of 0 or 1 to 4,
R 2 is a hydrogen atom, a linear or branched alkyl group having a carbon atom number of 1 to 10, or an aryl group optionally having a substituent, and
R 4 and R 5 are a hydroxyl group);
a surfactant; and
a mixed solvent of a hydrophobic organic solvent and water,
wherein the content of the gelator is 0.1-20% by mass with respect to the mass of the mixed solvent.

2 . The gel according to claim 1 , wherein the surfactant is at least one surfactant selected from among a nonionic surfactant, an anionic surfactant, or a cationic surfactant, the nonionic surfactant being selected from the group consisting of sorbitan monolaurate, sorbitan monostearate, sorbitan trioleate, polyoxyethylene sorbitan monolaurate, and polyoxyethylene sorbitan monooleate, the anionic surfactant being selected from the group consisting of sodium lauryl sulfate and di(2-ethylhexyl) sodium sulfosuccinate (AOT), and the cationic surfactant being selected from the group consisting of hexadecyltrimethylammonium bromide and cetylpyridinium chloride.

3 . The gel according to claim 1 , wherein the compound of Formula (1) is a compound of Formula (7) below

wherein, R 1 is as defined in Formula (1), and Me is a methyl group.

4 . The gel according to claim 1 , wherein the hydrophobic organic solvent is at least one selected from the group consisting of vegetable oils, esters, silicone oils, and hydrocarbons.

5 . A cosmetic or pharmaceutical base material containing the gel according to claim 1 .

6 . A cosmetic or pharmaceutical base material containing the gel according to claim 1 , and at least one polymeric compound.

7 . A method for preparing a W/O-type emulsion gel, the method comprising:
a step in which
a hydrophobic organic solvent and water,
0.1-20% by mass of a gelator with respect to the total mass of the hydrophobic organic solvent and the water, the gelator being composed of a compound of Formula (1) or (2) below

wherein, R 1 and R 3 are each independently a linear or branched alkyl group having a carbon atom number of 1 to 20, a cyclic alkyl group having a carbon atom number of 3 to 20, or a linear or branched alkenyl group having a carbon atom number of 2 to 20, n is an integer of 0 or 1 to 4,
R 2 is a hydrogen atom, a linear or branched alkyl group having a carbon atom number of 1 to 10, or an aryl group optionally having a substituent, and
R 4 and R 5 are a hydroxyl group, and
a surfactant are mixed, and the resultant mixture is dissolved via heating; and

a step for cooling the resultant solution.

Assignees

• Nissan Chemical Ind Ltd
• Univ Kyushu
• Institute Of Systems Information Tech And Nanotech
• Institute Of Systems Information Tech And Nanotech

Inventors

• Saruhashi Koichiro
• Hirata Osamu
• Ono Fumiyasu
• Shinkai Seiji
• Yamamoto Tatsuhiro

Classifications

• A61Q19/00

  Preparations for care of the skin · CPC title

• A61K8/042

  Gels · CPC title

• A61K8/31 Primary

  Hydrocarbons · CPC title

• A61K47/44

  Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin (synthetic glycerides, e.g. medium-chain triglycerides, A61K47/14) · CPC title

• A61K8/92

  Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof · CPC title