Atherosclerosis-targeted liposome nanocarrier delivery system and preparation method therefor
US-2024424132-A1 · Dec 26, 2024 · US
US2018271982A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2018271982-A1 |
| Application number | US-201515537723-A |
| Country | US |
| Kind code | A1 |
| Filing date | Dec 12, 2015 |
| Priority date | Dec 22, 2014 |
| Publication date | Sep 27, 2018 |
| Grant date | — |
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
What the patent document calls the invention.
A short plain-language summary of the technical disclosure.
Who owns or filed the patent and who is credited as inventor.
Filing, priority, publication, and grant dates set the timeline.
The legal scope of protection — read this for what is actually claimed.
Technology tags used to group this patent with similar filings.
Prior art links and similar publications in this corpus.
Official abstract text for this publication.
The present invention discloses liquid compositions that include an active compound, water, and means for inhibiting crystal formation or precipitation of the active compound in the liquid composition.
Opening claim text (preview).
What is claimed is: 1 . A liquid composition comprising: an active compound; water; and means for inhibiting crystal formation or precipitation of the active compound in the liquid composition. 2 . The liquid composition of claim 1 , wherein the active compound is lysine in a free base form. 3 . The liquid composition of claim 1 , wherein the means for inhibiting crystal formation or precipitation of the active compound is lecithin. 4 . The liquid composition of claim 1 , wherein the active compound is present in the liquid composition at a concentration above a crystallization point of the active compound. 5 . The liquid composition of claim 1 , wherein the liquid composition comprises less than 50% fat. 6 . The liquid composition of claim 1 , wherein the active compound is selected from the group consisting of an amino acid, ammonium sulfate, a dried biomass, a bioactive, a nutrient, an antioxidant, a polyol, a protein, a plant residue obtain from removing oil from the plant, and combinations of any thereof. 7 . The liquid composition of claim 6 , wherein the active compound is lysine. 8 . The liquid composition of claim 1 , wherein the means for inhibiting crystal formation or precipitation is present at a concentration of 0.1-5% by weight, at a concentration of between 0.5-4% by weight, at a concentration of between 1-3% by weight, or at a concentration of between 1-2% by weight. 9 . The liquid composition of claim 1 , wherein the means for inhibiting crystal formation or precipitation is lecithin. 10 . The liquid composition of claim 3 , wherein the lecithin is selected from the group consisting of crude filtered lecithin, fluid lecithin, de-oiled lecithin, chemically modified lecithin enzymatically modified lecithin, standardized lecithin, and combinations of any thereof. 11 . The liquid composition of claim 1 , further comprising a suspending agent. 12 . The liquid composition of claim 11 , wherein the suspending agent is a water soluble polymer. 13 . The liquid composition of claim 1 , wherein the lysine is present at an amount of at least 55% by weight, at least 60% by weight, at least 65% by weight, at least 70% by weight, at least 75% by weight, or at least 80% by weight. 14 . The liquid composition of claim 1 , wherein the means for inhibiting crystal formation or precipitation further comprises a co-emulsifier having an HLB of between 10-18. 15 . A method of preventing crystal formation or precipitation of an active compound in a liquid composition, the method comprising: mixing means for inhibiting crystal formation or precipitation of an active compound in an aqueous solution. 16 . The method of claim 15 , wherein the means for inhibiting crystal formation or precipitation of the active compound is lecithin. 17 . The method of claim 16 , wherein the active compound is lysine. 18 . (canceled) 19 . The method of claim 17 , wherein the lysine is in a free base form. 20 . A liquid composition comprising: an active compound; water; and lecithin; wherein the active compound is present in the liquid composition at a concentration above a crystallization point of the active compound
Alpha-amino acids, e.g. alanine or edetic acid [EDTA] (betaine A61K31/205; proline A61K31/401; tryptophan A61K31/405; histidine A61K31/4172; peptides not degraded to individual amino acids A61K38/00) · CPC title
Fatty acids; Fats; Products containing oils or fats · CPC title
Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin · CPC title
containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids · CPC title
Amino acids; Derivatives thereof · CPC title
Related publications grouped by family.
Answers are generated from the same data shown on this page.