Pharmaceutical composition for preventing or treating diabetic complications and angioedema, containing natural mixture extract as active ingredient
US-11191801-B2 · Dec 7, 2021 · US
US2018264058A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2018264058-A1 |
| Application number | US-201715792530-A |
| Country | US |
| Kind code | A1 |
| Filing date | Oct 24, 2017 |
| Priority date | Mar 15, 2017 |
| Publication date | Sep 20, 2018 |
| Grant date | — |
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The present disclosure relates to the field of health food technology, in particular to a traditional Chinese medicine composition, preparation method and use thereof. The traditional Chinese medicine composition is made from Poria, Angelicae Sinensis Radix, Aurantii Fructus Immaturus and Atractylodis Macrocephalae Rhizoma. The traditional Chinese medicine composition uses less species of Chinese herbs and has significant effect on reducing the circumference of waist and abdomen, reducing the weight of visceral fat and anti-inflammation by reasonable combination, and does not have side effects.
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1 . A traditional Chinese medicine composition, which is made from: Poria; Angelicae Sinensis Radix; Aurantii Fructus Immaturus ; and Atractylodis Macrocephalae Rhizoma. 2 . The traditional Chinese medicine composition according to claim 1 , wherein by weight, the dosage of each raw material is: Poria 10 to 90 parts; Angelicae Sinensis Radix 5 to 60 parts; Aurantii Fructus Immaturus 5 to 60 parts; and Atractylodis Macrocephalae Rhizoma 5 to 60 parts. 3 . The traditional Chinese medicine composition according to claim 1 , wherein by weight, the dosage of each raw material is: Poria 20 to 90 parts; Angelicae Sinensis Radix 10 to 40 parts; Aurantii Fructus Immaturus 10 to 40 parts; and Atractylodis Macrocephalae Rhizoma 10 to 40 parts. 4 . The traditional Chinese medicine composition according to claim 1 , wherein by weight, the dosage of each raw material is: Poria 30 parts; Angelicae Sinensis Radix 20 parts; Aurantii Fructus Immaturus 20 parts; and Atractylodis Macrocephalae Rhizoma 20 parts. 5 . A method for treating abdominal obesity in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of the traditional Chinese medicine composition according to claim 1 . 6 . The method according to claim 5 , wherein the treating abdominal obesity refers to one or more of reducing circumference of waist and abdomen, decreasing Lee's index, or reducing weight of visceral fat, improving the concentrations of inflammation-related factors IL-10, IL-18, PAI-1, adiponectin, TNF-α, IL6 and CRP in serum. 7 . A method for preparing the traditional Chinese medicine composition according to claim 1 , comprising: mixing Poria, Angelicae Sinensis Radix, Aurantii Fructus Immaturus and Atractylodis Macrocephalae Rhizoma; adding water and soaking; decocting; and filtering to obtain the traditional Chinese medicine composition. 8 . The method according to claim 7 , wherein the water is 3 to 10 times by weight as much as the raw materials; soaking time is 0.25 h to 2 h; numbers to decoct is 1 to 5 times; time of each decoction is 1 h to 4 h. 9 . A health food, comprising the traditional Chinese medicine composition according to claim 1 .
Poria · CPC title
Angelica · CPC title
Citrus, e.g. lime, orange or lemon · CPC title
Atractylodes · CPC title
Anorexiants; Antiobesity agents · CPC title
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