Vena-caval occlusion element

Patent metadata

Field	Value
Publication number	US-2018228951-A1
Application number	US-201815888771-A
Country	US
Kind code	A1
Filing date	Feb 5, 2018
Priority date	Mar 13, 2013
Publication date	Aug 16, 2018
Grant date	—

Abstract

Apparatus and methods are described including a catheter, a first pump disposed on the catheter, and a second pump disposed on the catheter, proximally to the first pump. A control unit is configured to control activation of the first and second pumps. The first and second pumps are configured, when activated, to pump fluid in opposite directions from one another. Other applications are also described.

First claim

1 - 68 . (canceled)

69 . Apparatus, comprising:
an occlusion element configured to be placed inside a vena cava of a subject at a first location that is upstream of junctions of the vena cava with all renal veins of the subject, and to partially occlude the vena cava at the location; one or more sensors configured to detect one or more physiological parameter of the subject; and a computer processor configured to modulate an extent to which the occlusion element occludes the vena cava at the location, responsively to the one or more detected physiological parameters of the subject.

70 . The apparatus according to claim 69 , wherein the one or more sensors comprise one or more sensors selected from the group consisting of: a pressure sensor configured to detect venous blood pressure at a second location that is upstream of the occlusion element, a pressure sensor configured to detect venous blood pressure at a third location that is downstream of the occlusion element, a flow sensor, a thermal flow sensor, and an oxygen-saturation sensor.

71 . The apparatus according to claim 69 , wherein the occlusion element comprises a balloon, and wherein the computer processor is configured modulate the extent to which the occlusion element occludes the vena cava at the location by controlling inflation of the balloon.

72 . The apparatus according to claim 69 , wherein the occlusion element comprises a frame that is covered in a blood-impermeable material, and wherein the computer processor is configured modulate the extent to which the occlusion element occludes the vena cava at the location by controlling expansion of the frame.

73 . The apparatus according to claim 72 , wherein the computer processor is configured to control expansion of the frame by heating the frame.

74 . The apparatus according to claim 72 , wherein the computer processor is configured to control expansion of the frame by applying an electrical current to the frame.

75 . A method, comprising:
partially occluding a vena cava of a subject at a first location that is upstream of junctions of the vena cava with all renal veins of the subject; detecting one or more physiological parameter of the subject; and modulating an extent to which the vena cava is occluded at the location, responsively to the one or more detected physiological parameters of the subject.

76 . The method according to claim 75 , wherein detecting one or more physiological parameter of the subject comprises detecting one or more physiological parameter of the subject, the one or more physiological parameters being selected from the group consisting of: venous blood pressure at a second location that is upstream of the first location, venous blood pressure at a third location that is downstream of the first location, blood flow, and oxygen saturation.

77 . The method according to claim 75 , wherein partially occluding the subject's vena cava at the location comprises partially occluding the subject's vena cava at the location with a balloon, and wherein modulating the extent to which the vena cava is occluded at the location comprises controlling inflation of the balloon.

78 . The method according to claim 75 , wherein partially occluding the subject's vena cava at the location comprises partially occluding the subject's vena cava at the location with a frame that is covered in a blood-impermeable material, and wherein modulating the extent to which the vena cava is occluded at the location comprises controlling expansion of the frame.

79 . The method according to claim 78 , wherein controlling expansion of the frame comprises heating the frame.

80 . The method according to claim 78 , wherein controlling expansion of the frame comprises applying an electrical current to the frame.

81 . Apparatus, comprising:
a blood pump configured to be placed inside a vena cava of a subject at a first location that is upstream of junctions of the vena cava with all renal veins of the subject, and pump blood in a retrograde direction through the vena cava at the location; one or more sensors configured to detect one or more physiological parameter of the subject; and a computer processor configured to modulate a rate at which the blood pump pumps the blood in the retrograde direction through the vena cava, responsively to the one or more detected physiological parameters of the subject.

82 . The apparatus according to claim 81 , wherein the one or more sensors comprise one or more sensors selected from the group consisting of: a pressure sensor configured to detect venous blood pressure at a second location that is upstream of the pump, a pressure sensor configured to detect venous blood pressure at a third location that is downstream of the pump, a flow sensor, a thermal flow sensor, and an oxygen-saturation sensor.

83 . A method, comprising:
pumping blood in a retrograde direction through a vena cava of a subject at a first location within the vena cava that is upstream of junctions of the vena cava with all renal veins of the subject; detecting one or more physiological parameter of the subject; and modulating a rate at which the blood is pumped in the retrograde direction through the vena cava, responsively to the one or more detected physiological parameters of the subject.

84 . The method according to claim 83 , wherein detecting one or more physiological parameter of the subject comprises detecting one or more physiological parameter of the subject, the one or more physiological parameters being selected from the group consisting of: venous blood pressure at a second location that is upstream of the first location, venous blood pressure at a third location that is downstream of the first location, blood flow, and oxygen saturation.

Assignees

• Magenta Medical Ltd

Inventors

• Schwammenthal Ehud
• Tuval Yosi
• Glozman Daniel

Classifications

• A61B2017/12127

  Double occlusion, e.g. for creating blood-free anastomosis site · CPC title

• A61B17/12168

  having a mesh structure (A61B17/1214 takes precedence) · CPC title

• A61M2230/30

  Blood pressure (A61M2230/04 takes precedence) · CPC title

• A61M2205/505

  Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches · CPC title

• A61M2205/80

  voice-operated command · CPC title