Postoperative modification of an intraocular lens

Patent metadata

Field	Value
Publication number	US-2018200112-A1
Application number	US-201615746415-A
Country	US
Kind code	A1
Filing date	Jul 6, 2016
Priority date	Jul 22, 2015
Publication date	Jul 19, 2018
Grant date	—

Abstract

Systems and methods for localizing intraocular lens and/or existing refractive index patterns, to laser write-patterns, and to refractive index patterns in order to modify the refractive index by application of femtosecond laser pulses. OCT-based confocal detection and sectional image systems are provided for localization purposes, the systems being particularly suitable for the detection of phase patterns in addition to the localization of the IOL. With respect to laser write-patterns, the modification of existing refractive index patterns in the IOL is carried out by destroying existing structures or supplementing existing refractive index patterns.

First claim

1 .- 19 . (canceled)

20 . A system for refractive index modification of IOL with a femtosecond laser, comprising:
a femtosecond pulse laser system that has a femtosecond laser source a lens, which focuses the laser beam in the eye and the IOL, and a scanner, which scans the focal point at the laser beam laterally and axially to the optical axis of the lens; an optical coherence tomography (OCT) measurement/imaging system that has an OCT light source/OCT detector and a lateral scanner, which conducts the light of the OCT light source into the eye via the same lens that is used for the femtosecond pulse laser beam and detects the light reflected by the eye or its inner structures; a control device, which analyzes signals from the OCT system to determine a position of the IOL in the eye, a shape of the IOL or both a position and a shape of the IOL in the eye, and which controls the femtosecond pulse laser system to apply a writing pattern in the IOL.

21 .- 25 . (canceled)

26 . A system for refractive index modification of an IOL with a femtosecond laser, comprising:
a femtosecond pulse laser system that has a femtosecond laser source, a lens, which focuses the laser beam in the eye and the IOL, and a scanner, which scans the focal point of the laser beam laterally and axially to the optical axis of the lens. an optical coherence tomography (OCT) measurement/imaging system that has an OCT light source/detector and a lateral scanner, which conducts the light of the OCT light source into the eye also through the lens which focuses the laser beam in the eye, and detects the light reflected by the eye or its inner structures; a confocal detection measurement/imaging system that has a light source/detector and a lateral scanner, which conducts the light of the light source into the eye also through the lens which focuses the laser beam in the eye, and detects the light reflected by the eye or its inner structures; a control device, which analyzes signals from the confocal system in order to determine the position and/or shape of the IOL in the eye, which analyzes the signals of the OCT system in order to record the position and/or expansion of a refractive index pattern inside the IOL in three dimensions, and which controls the laser system for the application of the writing pattern.

27 . The system according to claim 26 , wherein the lens acts as a scanning element.

28 . The system according to claim 26 , wherein the scanner and the lateral scanner are the same scanner.

29 . A method for refractive index modification of an IOL by application of femtosecond laser pulses, comprising:
recording a measurement and imaging signal of the eye or of structures in the eye; locating a position of the IOL, a location of the IOL in the eye or both a position and a location of the IOL in the eye in the measurement and imaging signal; and writing a writing pattern of femtosecond laser pulses in the IOL, taking into account data obtained regarding the position, the location or both the position and the location of the IOL in the eye.

30 . The method according to claim 29 , further comprising:
locating at least one of a position, a location or dimensions of a pre-existing refractive index pattern inside the IOL; writing the writing pattern of femtosecond laser pulses in the IOL, taking into account, in addition to the data obtained regarding the position, the location or both the position and the location of the IOL, in the eye, data regarding at least one of the position, location or dimensions of a refractive index pattern inside the IOL.

31 . The method according to claim 29 , further comprising: writing a first writing pattern in a previously untreated IOL, axially posterior—with respect to an optical axis of the IOL—to a middle of the previously untreated IOL.

32 . The method according to claim 29 , further comprising: writing a first or further writing pattern of femtosecond laser pulses in the IOL to correct a previously existing multi-focal structure or the IOL, at most 200 μm posterior or anterior to the previously existing multi-focal structure.

33 . The method according to claim 30 , further comprising: writing a further writing pattern to correct a previously existing refractive index pattern or writing pattern.

34 . The method according to claim 33 , comprising writing the further writing pattern at an axial position to the eye axis, anterior to the previously existing refractive index pattern.

35 . The method according to claim 33 , further comprising writing a writing pattern such that it surrounds or embeds a pre-existing refractive index pattern.

36 . The method according to claim 35 , wherein the pre-existing refractive index pattern and the supplemented refractive index pattern collectively form a geometrically simple, coherent refractive index pattern that does not have a diffractive optical effect, or an optical effect corresponding to a wrapped lens.

37 . The method according to claim 35 , wherein the writing pattern and the previously existing refractive index pattern overlap.

38 . The method according to claim 33 , wherein the previously existing refractive index pattern is erased by the writing pattern.

39 . The method according to claim 33 , wherein the writing pattern completely covers the previously existing refractive index pattern, and also covers parts of the IOL region that has not been inscribed.

40 . The method according to claim 30 ,
further comprising using OCT signals to calculate the position of the refractive index pattern and the position of the IOL in relation to the coordinate system of an OCT system, further comprising using confocal detection signals to calculate the position of the IOL in relation to the coordinate system of a confocal detection system, further comprising calculating a coordinate transformation of the IOL position in relation to the coordinate system of the OCT system and the IOL position in relation to the coordinate system of the confocal detection system, further comprising converting the position of the refractive index pattern in relation to the coordinate system of the OCT system on the basis of the coordinate transformation to a position of the refractive index pattern in relation to the coordinate system of the confocal detection system, and further comprising using position data of the IOL and the refractive index pattern in relation to the coordinate system of the confocal detection system for calculating the writing pattern.

41 . The method according to claim 29 , further comprising writing the writing pattern in the IOL to convert:
a mono-focal IOL into a multi-focal IOL, a multi-focal IOL into a mono-focal IOL, or
a non-prismatic IOL into an IOL with a supplementary prismatic effect.

Assignees

• Zeiss Carl Meditec Ag

Inventors

• Krampert Gerhard
• Kindt Johannes
• Bublitz Daniel
• Pomraenke Robert
• Kühner Martin

Classifications

• A61F2009/0087

  Lens · CPC title

• A61F2009/00887

  Cataract · CPC title

• A61F9/00834 Primary

  Inlays; Onlays; Intraocular lenses [IOL] · CPC title

• A61F9/0084

  Laser features or special beam parameters therefor · CPC title

• A61F2009/00844

  Feedback systems · CPC title