18f - tagged inhibitors of prostate specific membrane antigen (psma) and their use as imaging agents for prostate cancer

US2018194729A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2018194729-A1
Application numberUS-201815915978-A
CountryUS
Kind codeA1
Filing dateMar 8, 2018
Priority dateSep 30, 2015
Publication dateJul 12, 2018
Grant date

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

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The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers and imaging agents for various disease states of prostate cancer.

First claim

Opening claim text (preview).

What is claimed is: 1 . A compound of Formula I: with: i, j 0, 1 m 1-5 n 0-3 R H, CH 3 AS Natural or non-natural amino acid Z: —CO 2 H, —SO 2 H, —SO 3 H, —SO 4 H, —PO 2 H, —PO 3 H, —PO 4 H 2 X: Naphthyl, Phenyl, Biphenyl, Indolyl (═2,3-benzopyrrolyl), Benzothiazolyl, Quinoyl Y: Aryl, Alkylaryl, Cyclopentyl, Cyclohexyl, Cycloheptyl, N-Piperidyl and N-methylated Piperidyl salt 18 F-Tag: With: x = 1-5 Carboydrate:

Assignees

Inventors

Classifications

  • of the prostate · CPC title

  • Antineoplastic agents · CPC title

  • Medicinal preparations containing peptides (peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00) · CPC title

  • Organic compounds · CPC title

  • C07D213/61Primary

    Halogen atoms or nitro radicals · CPC title

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Frequently asked questions

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What does patent US2018194729A1 cover?
The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers and imaging agents for various disease states of prostate cancer.
Who is the assignee on this patent?
Deutsches Krebsforsch, Univ Heidelberg Ruprecht Karls
What technology area does this patent fall under?
Primary CPC classification C07D213/61. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Thu Jul 12 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).