Magnetoelastic implantable actuation device and method

Patent metadata

Field	Value
Publication number	US-2018177638-A1
Application number	US-201615739625-A
Country	US
Kind code	A1
Filing date	Jun 24, 2016
Priority date	Jun 25, 2015
Publication date	Jun 28, 2018
Grant date	—

Abstract

An implantable actuation device that may be used with a glaucoma drainage device or attached to an ocular surface, a method of making an implantable actuation device, and a method of preventing cell adhesion resulting from a glaucoma treatment procedure. The implantable actuation device is made from a magnetoelastic material. Actuation of the magnetoelastic material may help control cellular adhesion that may develop and undesirably disrupt proper healing when recovering from invasive surgical treatments. The implantable actuation devices may have small form factors and customized geometries which include three-dimensional curvatures to help promote the actuation of liquid flow and facilitate the removal of unwanted cells.

First claim

1 . An implantable actuation device, comprising:
an anchor adapted for fixedly mounting the implantable actuation device to a surface; an actuating paddle comprised of a magnetoelastic material; and a suspension component having a first end attached to the anchor and a second end attached to the actuating paddle, wherein the suspension component allows for relative movement between the fixedly mounted anchor and the actuating paddle when the implantable actuation device is mounted to the surface.

2 . The implantable actuation device of claim 1 , wherein the anchor is fixedly mounted to an ocular surface.

3 . The implantable actuation device of claim 1 , wherein the actuating paddle includes a panel portion and a strip portion.

4 . The implantable actuation device of claim 1 , comprising a plurality of anchors and a plurality of suspension components.

5 . The implantable actuation device of claim 4 , comprising a plurality of actuating paddles.

6 . The implantable actuation device of claim 5 , wherein two actuating paddles are connected via a central anchor.

7 . The implantable actuation device of claim 4 , wherein the actuating paddle extends between two anchors attached via two suspension components.

8 . The implantable actuation device of claim 1 , wherein the actuating paddle has a three-dimensional, non-spherically shaped profile.

9 . A glaucoma drainage device, comprising:
a body having a surface; a drainage tube attached to the body; and the implantable actuation device of claim 1 , wherein the anchor of the implantable actuation device is fixedly mounted to the surface of the body of the glaucoma drainage device.

10 . The glaucoma drainage device of claim 9 , comprising a plurality of implantable actuation devices.

11 . An implantable ocular actuation device, comprising:
a magnetoelastic membrane having a three-dimensional, non-spherically shaped profile.

12 . A glaucoma drainage device comprising the implantable ocular actuation device of claim 11 .

13 . A method of fabricating an implantable ocular actuation device comprising the steps of:
patterning a magnetoelastic alloy membrane; and annealing the membrane to shape it so that the membrane has a three-dimensional, non-spherically shaped profile.

14 . The method of claim 13 , further comprising the step of coating the membrane with a biocompatible material.

15 . A method of preventing cell adhesion resulting from a glaucoma treatment procedure, comprising the steps of:
anchoring a magnetoelastic paddle actuator to an ocular surface or a surface of a glaucoma drainage device; and wirelessly applying a magnetic field to the magnetoelastic paddle actuator so that the paddle actuator vibrates and dispels at least some fibroblasts from the paddle actuator itself, the ocular surface, and/or the surface of the glaucoma drainage device.

16 . The method of claim 15 , wherein the magnetoelastic paddle actuator has a three-dimensional, non-spherically shaped profile.

17 . The method of claim 15 , wherein vibratory motion of the magnetoelastic paddle actuator is out of plane.

Assignees

• Univ Michigan Regents

Inventors

• Stein Joshua D
• Gianchandani Yogesh
• Pepakayala Venkatram

Classifications

• A61M27/002

  Implant devices for drainage of body fluids from one part of the body to another (intraocular A61F9/00781; middle ear A61F11/202) · CPC title

• A61F2250/0013

  for adjusting fluid pressure · CPC title

• A61F9/00781 Primary

  Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment (drainage implants in general A61M27/002) · CPC title