Utilization of electrode spatial arrangements for characterizing cardiac conduction conditions

Patent metadata

Field	Value
Publication number	US-2018153428-A1
Application number	US-201715725128-A
Country	US
Kind code	A1
Filing date	Oct 4, 2017
Priority date	May 7, 2013
Publication date	Jun 7, 2018
Grant date	—

Abstract

A system and method are provided for determining electrophysiological data. The system comprises an electronic control unit that is configured to receive electrical signals from a set of electrodes, receive position and orientation data for the set of electrodes from a mapping system, compensate for position and orientation artifacts of the set of electrodes, compose cliques of a subset of neighboring electrodes in the set of electrodes, determine catheter orientation independent information of a target tissue, and output the orientation independent information to a display. The method comprising receiving electrogram data for a set of electrodes ( 80 ), compensating for artifacts in sensor positions in the mapping system ( 81 ), resolving the bipolar signals into a 3D vector electrogram in the mapping system coordinates ( 82 ), manipulating observed unipolar voltage signals and the tangent component of the e-field to estimate the conduction velocity vector ( 83 ), and outputting the catheter orientation independent information ( 84 ).

First claim

1 .- 20 . (canceled)

21 . A system for determining electrophysiological data, comprising:
an electronic control unit configured to:
receive electrogram data for a set of electrodes,
compose a clique of at least three neighboring electrodes from the set of electrodes, wherein the electrogram data comprises a plurality of signals taken from the at least three neighboring electrodes in the clique;
receive position and orientation information for the set of electrodes from a mapping system;
derive an E-field from the plurality of signals of the clique;
determine catheter orientation independent information of a tissue based on the electrogram data and position and orientation information from the set of electrodes, wherein the catheter orientation independent information comprises a local tangent E-field and an orthogonal unit vector in the direction along which the wavefront is propagating (â); and
output the orientation independent information to a user or process.

22 . The system according to claim 21 , wherein the orientation independent information further comprises at least one of a 2D vector electric field, a 3D vector electric field, a normal electric field, the eccentricity of the tangent electric field loop, derived normal and tangent bipolar electrogram signals, a wavefront conduction velocity, or a unit direction vector.

23 . The system according to claim 21 , wherein the electronic control unit is further configured to compensate for artifacts in the position and orientation information received from the mapping system.

24 . The system according to claim 21 , wherein the electronic control unit is further configured to resolve the electrogram data into a 3D vector electrogram in a coordinate system of the mapping system.

25 . The system according to claim 21 , wherein the catheter orientation independent information further comprises a wavefront conduction velocity and a 2D vector electric field.

26 . The system according to claim 21 , wherein the electronic control unit is further configured to resolve the electrogram data into a 2D vector electrogram in a coordinate system of the mapping system.

27 . The system according to claim 26 , wherein the catheter orientation independent information further comprises a conduction velocity magnitude.

28 . The system according to claim 21 , wherein the plurality of signals comprise unipole signals.

29 . The system according to claim 21 , wherein the plurality of signals comprise bipolar signals.

30 . The system according to claim 21 , wherein the plurality of signals are received when the at least three neighboring electrodes in the clique are in contact with a tissue.

31 . A system for determining electrophysiological data, comprising:
an electronic control unit configured to:
receive electrical signals from a set of electrodes;
receive position and orientation data for the set of electrodes from a mapping system;
compensate for position and orientation artifacts of the set of electrodes;
compose cliques of a subset of neighboring electrodes in the set of electrodes, wherein each of the cliques comprise at least three electrodes, wherein the electrical signals comprise a plurality of signals taken from the at least three neighboring electrodes in each of the cliques;
derive an E-field for a tissue adjacent to each of the cliques from the plurality of signals;
determine catheter orientation independent information of a target tissue based on the electrogram data and position and orientation information from the set of electrodes, wherein the catheter orientation independent information comprises a local tangent E-field and an orthogonal unit vector in the direction along which the wavefront is propagating (â); and
output the orientation independent information to a display.

32 . The system according to claim 31 , wherein the orientation independent information further comprises a local estimate of the conduction velocity vector.

33 . The system according to claim 31 , wherein the plurality of signals are received when the at least three neighboring electrodes in the clique are in contact with a tissue.

34 . The system according to claim 31 , wherein the plurality of signals comprise bipolar signals.

35 . A method of determining electrophysiological data, comprising:
receiving electrogram data for a set of electrodes, composing a clique of at least three neighboring electrodes from the set of electrodes, wherein the electrogram data comprises a plurality of signals taken from the at least three neighboring electrodes in the clique; receiving position and orientation information for the set of electrodes from a mapping system; deriving an E-field from the plurality of signals; determining catheter orientation independent information of a tissue based on the electrogram data and position and orientation information from the set of electrodes, wherein the catheter orientation independent information comprises a local tangent E-field and an orthogonal unit vector in the direction along which the wavefront is propagating (â); and outputting the orientation independent information to a user or process.

36 . The method according to claim 35 , wherein the orientation independent information further comprises at least one of a 2D vector electric field, a 3D vector electric field, a normal electric field, the eccentricity of the tangent electric field loop, derived normal and tangent bipolar electrogram signals, a wavefront conduction velocity, or a unit direction vector.

37 . The method according to claim 35 further comprising compensating for artifacts in the position and orientation information received from the mapping system.

38 . The method according to claim 35 , wherein the plurality of signals comprise bipolar signals.

39 . The method according to claim 35 , wherein the orientation independent information further comprises a local estimate of the conduction velocity vector.

40 . The method according to claim 39 , wherein the plurality of signals are received when the at least three neighboring electrodes in the clique are in contact with a tissue.

Assignees

• St Jude Medical Atrial Fibrillation Div Inc

Inventors

• Balachandran Ram K
• Deno D Curtis

Classifications

• A61B2017/00039

  Electric or electromagnetic phenomena other than conductivity, e.g. capacity, inductivity, Hall effect · CPC title

• A61B2017/00044

  Sensing electrocardiography, i.e. ECG · CPC title

• A61B5/7203

  for noise prevention, reduction or removal · CPC title

• A61B2218/002

  Irrigation · CPC title

• A61B34/20

  Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis · CPC title