Blood gas exchanger with restriction element or elements to reduce gas exchange

Patent metadata

Field	Value
Publication number	US-2018133388-A1
Application number	US-201515571548-A
Country	US
Kind code	A1
Filing date	May 12, 2015
Priority date	May 12, 2015
Publication date	May 17, 2018
Grant date	—

Abstract

A gas exchanger with a restriction element or elements to reduce gas exchange as desired to avoid hypo-capnia and hyper-oxygenation in small patients. The gas exchanger includes a gas exchanger housing with an outer wall and a core which defines an inner wall and having a blood inlet for receiving a blood supply and a blood outlet. The gas exchanger also includes a hollow fiber bundle disposed within the housing between the core and the outer wall, and a gas inlet compartment for receiving an oxygen supply and directing the oxygen supply to the first ends of the hollow fiber bundle, wherein the gas inlet compartment includes at least one restriction element configured to allow the oxygen supply to reach only a portion of the hollow fiber bundle.

First claim

1 - 20 . (canceled)

21 . A gas exchanger comprising:
a gas exchanger housing including an outer wall and a core which defines an inner wall and having a blood inlet for receiving a blood supply and a blood outlet, the gas exchanger housing defining a gas exchanger volume; a hollow fiber bundle disposed within the housing between the core and the outer wall, the hollow fiber bundle comprising hollow gas permeable fibers, each fiber having first and second ends and a hollow interior; and a gas inlet compartment for receiving an oxygen supply and directing the oxygen supply to the first ends of the hollow gas permeable fibers; wherein the gas inlet compartment includes at least one restriction element configured to allow the oxygen supply to reach only a portion of the hollow gas permeable fibers.

22 . The gas exchanger of claim 21 , wherein the at least one restriction element comprises a gasket.

23 . The gas exchanger of claim 21 , wherein the at least one restriction element is moveable such that the at least one restriction element can assume a first position that is opened in order to allow the oxygen supply to reach all of the hollow gas permeable fibers and a second position that is closed such that the oxygen supply only reaches a portion of the hollow gas permeable fibers.

24 . The gas exchanger of claim 21 , wherein the gas exchanger includes at least two restriction elements and the at least two restriction elements are concentrically arranged.

25 . The gas exchanger of claim 21 , wherein the gas exchanger housing is tubular in shape, the gas inlet compartment includes a gas inlet that is located at or near the center of the lid, and the at least one restriction element concentrically surrounds the gas inlet.

26 . The gas exchanger of claim 21 , wherein 50% of the fiber bundle is provided with oxygen supply for a small, neonatal patient.

27 . A gas exchanger comprising:
a gas exchanger housing including an outer wall, at least one lid, and a core which defines an inner wall and having a blood inlet for receiving a blood supply and a blood outlet, the gas exchanger housing defining a gas exchanger volume; a hollow fiber bundle disposed within the housing between the core and the outer wall, the hollow fiber bundle comprising hollow gas permeable fibers, each fiber having first and second ends and a hollow interior, wherein the first ends of the hollow gas permeable fibers are located in a first potting that is located at or near the lid; and a gas inlet compartment including a gas inlet for receiving an oxygen supply and directing the oxygen supply to the first ends of the hollow gas permeable fibers; wherein the gas inlet compartment includes at least one restriction element that concentrically surrounds the gas inlet, wherein the one or more restriction elements are moveable such that the one or more restriction elements can assume a first position that is open in order to allow the oxygen supply to reach all of the first ends of the hollow gas permeable fibers and a second position that is compressed against the potting such that the oxygen supply only reaches a portion of the hollow gas permeable fibers.

28 . The gas exchanger of claim 27 , further comprising at least one rigid lever that is connected to the at least one restriction element and that is configured to move the at least one restriction element between the first and second positions.

29 . The gas exchanger of claim 27 , wherein the gas inlet compartment is located within the at least one lid.

30 . The gas exchanger of claim 27 , wherein the oxygenator includes at least two restriction elements and the at least two restriction elements are concentrically arranged.

31 . The gas exchanger of claim 27 , wherein the at least one restriction element comprises a gasket.

32 . The gas exchanger of claim 27 , wherein 50% of the fiber bundle is provided with oxygen supply for a small, neonatal patient.

33 . A method of oxygenation comprising:
providing a gas exchanger comprising: a gas exchanger housing including an outer wall and a core which defines an inner wall and having a blood inlet for receiving a blood supply and a blood outlet, the gas exchanger housing defining a gas exchanger volume; a hollow fiber bundle disposed within the housing between the core and the outer wall, the hollow fiber bundle comprising hollow gas permeable fibers, each fiber having first and second ends, hollow interior and an exterior; and a gas inlet compartment for receiving an oxygen supply and directing the oxygen supply to the first ends of the hollow gas permeable fibers; wherein the gas inlet compartment includes at least one restriction element configured to allow the oxygen supply to reach only a portion of the hollow gas permeable fibers; activating the at least one restriction element; causing the oxygen supply to flow through the hollow interior of the portion of the hollow gas permeable fibers; delivering blood to the gas exchanger through the blood inlet; causing the blood to flow through the gas exchanger housing over the exterior of the hollow gas permeable fibers; and discharging the blood through the blood outlet.

34 . The method of claim 33 , wherein the at least one restriction element comprises a gasket.

35 . The method of claim 33 , wherein the at least one restriction element is moveable such that the at least one restriction element can assume a first position that is open in order to allow the oxygen supply to reach all of the hollow gas permeable fibers and a second position that is closed such that the oxygen supply only reaches a portion of the hollow gas permeable fibers.

36 . The method of claim 35 , wherein activating the at least one restriction element comprises moving the at least one restriction element to the second position.

37 . The method of claim 33 , wherein the gas exchanger includes at least two restriction elements and the at least two restriction elements are concentrically arranged.

38 . The method of claim 33 , wherein the gas exchanger housing is tubular in shape, the gas inlet compartment includes a gas inlet that is located at or near the center of the lid, and the at least one restriction element concentrically surrounds the gas inlet.

39 . The method of claim 33 , wherein the at least one restriction element concentrically surrounds the gas inlet, wherein the one or more restriction elements are moveable such that the one or more restriction elements can assume a first position that is open in order to allow the oxygen supply to reach all of the first ends of the hollow gas permeable fibers and a second position that is compressed against the potting such that the oxygen supply only reaches a portion of the hollow gas permeable fibers.

40 . The method of claim 33 , wherein 50% of the fiber bundle is provided with oxygen supply for a small, neonatal patient.

Assignees

• Sorin Group Italia Srl

Inventors

• Mazzoli Adriano
• Reggiani Stefano

Classifications

• B01D2313/19

  Specific flow restrictors · CPC title

• A61M1/1698 Primary

  Blood oxygenators with or without heat-exchangers (intracorporal A61M1/1678; manufacturing of membranes therefor B01D67/00; semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi-permeable membranes characterised by their material B01D71/00) · CPC title

• B01D2313/08

  Flow guidance means within the module or the apparatus · CPC title

• A61M1/26

  {and internal elements} which are moving · CPC title

• B01D63/02

  Hollow fibre modules · CPC title