Diagnostic chip

Patent metadata

Field	Value
Publication number	US-2018024155-A1
Application number	US-201515546867-A
Country	US
Kind code	A1
Filing date	Jan 30, 2015
Priority date	Jan 30, 2015
Publication date	Jan 25, 2018
Grant date	—

Abstract

A microfluidic diagnostic chip may comprise a substrate, a plurality of fluidic slots extending through the substrate, a plurality of microfluidic channels each coupled to a respective one of the plurality of fluidic slots to receive a plurality of fluids from the plurality of fluidic slots, and a mixing region in fluid communication with the plurality of fluidic slots to receive the plurality of fluids such that the plurality of fluids are to mix. A diagnostic chip may comprise a number of fluid slots defined through a substrate and a plurality of microfluidic channels coupled to the fluid slots to receive from the fluid slots a plurality of different fluids wherein the microfluidic channels combine and mix the plurality of different fluids.

First claim

What is claimed is:

1 . A microfluidic diagnostic chip, comprising:
a substrate; a plurality of fluidic slots extending through the substrate; a plurality of microfluidic channels each coupled to a respective one of the plurality of fluidic slots to receive a plurality of fluids from the plurality of fluidic slots; and a mixing region in fluid communication with the plurality of fluidic slots to receive the plurality of fluids such that the plurality of fluids are to mix.

2 . The microfluidic diagnostic chip of claim 1 , wherein each of the plurality of microfluidic channels comprise at least one micropump.

3 . The microfluidic diagnostic chip of claim 2 , wherein the micropumps cooperate to cause the plurality of fluids to pass through the respective microfluidic channels to mix the plurality of fluids to produce a specified composition of the plurality of fluids.

4 . The microfluidic diagnostic chip of claim 3 , wherein a number of the plurality of microfluidic channels comprise a number of sensors to detect properties of the fluids.

5 . The microfluidic diagnostic chip of claim 4 , wherein the number of sensors are to detect the properties of the fluids before mixing.

6 . The microfluidic diagnostic chip of claim 4 , wherein the number of sensors are to detect the properties of the fluids after mixing.

7 . The microfluidic diagnostic chip of claim 4 , wherein the number of sensors are to detect impedance values of the fluids.

8 . A diagnostic chip, comprising:
a number of fluid slots defined through a substrate; and a plurality of microfluidic channels each coupled to a respective one of the fluid slots to receive from the fluid slots a plurality of different fluids; wherein the microfluidic channels are to combine the plurality of different fluids in a combining region.

9 . The diagnostic chip of claim 8 , wherein each of the plurality of microfluidic channels comprise at least one rnicropump.

10 . The diagnostic chip of claim 9 , wherein the micropumps cooperate to combine the plurality of fluids to produce a specified composition of the plurality of fluids.

11 . The diagnostic chip of claim 8 , wherein a number of the plurality of microfluidic channels comprise a number of sensors to detect properties of the fluids.

12 . The diagnostic chip of claim 8 , wherein the microfluidic channels are fluidly coupled to an uppermost level of the fluid slots defined in the substrate.

13 . The diagnostic chip of claim 11 , wherein each sensor is electrically coupled to an electrode for coupling the diagnostic chip to a computing device.

14 . A method of forming a microfluidic diagnostic chip, comprising:
forming a plurality of distinct fluid slots through a substrate; forming a plurality of microfluidic channels each fluidly coupled at their respective first ends to a respective one of the plurality of fluid slots and joining at their respective second ends in a mixing region; and forming a number of sensors within a number of the plurality of the microfluidic channels.

15 . The method of claim 14 , further comprising forming a number of microfluidic pumps within a number of the plurality of microfluidic channels.

Assignees

• Hewlett Packard Development Co Lp

Inventors

• Mcguinness Nicholas Matthew Cooper
• Domingue Chantelle Elizabeth
• Giri Manish
• Friesen Ed

Classifications

• B01L2300/0861

  Configuration of multiple channels and/or chambers in a single devices · CPC title

• B01L2200/10

  Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept · CPC title

• B01L2200/04

  Exchange or ejection of cartridges, containers or reservoirs · CPC title

• B01L2300/0627

  Sensor or part of a sensor is integrated · CPC title

• B01L2300/0867

  Multiple inlets and one sample wells, e.g. mixing, dilution · CPC title