Expression of foxp3 in edited cd34+ cells
US-2024117352-A1 · Apr 11, 2024 · US
US2017349882A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2017349882-A1 |
| Application number | US-201715610733-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jun 1, 2017 |
| Priority date | Jun 2, 2016 |
| Publication date | Dec 7, 2017 |
| Grant date | — |
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Provided is a cell culture substrate for trait induction control of a macrophage, which has a pattern of unevenness on a surface to which a cell adheres, the width of the unevenness being 50 nm or more and less than 1,000 nm.
Opening claim text (preview).
What is claimed is: 1 . A cell culture substrate for trait induction control of a macrophage, which has a pattern of unevenness on a surface to which a cell adheres, the width of the unevenness being 50 nm or more and less than 1,000 nm. 2 . The cell culture substrate for trait induction control of a macrophage according to claim 1 , wherein the pattern of unevenness is a lattice shape, a radial shape, a polygon continuous shape on a flat surface, a labyrinthine shape, a line shape, or a dot shape. 3 . A method of controlling trait of a macrophage, comprising: culturing a macrophage on the cell culture substrate for trait induction control of a macrophage according to claim 1 . 4 . The method of controlling trait of a macrophage according to claim 3 , wherein a culturing time of the macrophage is 1 hour or more and 100 hours or less. 5 . The method of controlling trait of a macrophage according to claim 3 , wherein the macrophage is trait-induced into foam cell.
Patterned coating · CPC title
Macrophages, e.g. Kuepfer cells in the liver; Monocytes · CPC title
Lipopolysaccharides [LPS] · CPC title
Interleukin-4 (IL-4) · CPC title
Interferons [IFN] · CPC title
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