Dry powder nebulizer

Patent metadata

Field	Value
Publication number	US-2017340845-A1
Application number	US-201715676705-A
Country	US
Kind code	A1
Filing date	Aug 14, 2017
Priority date	Mar 8, 2010
Publication date	Nov 30, 2017
Grant date	—

Abstract

A dry powder delivery device may be configured to provide micronized dry powder particles to airways of a user. The device may include a cylindrical container delimiting a chamber containing at least one magnetically-responsive object, a motor external to said chamber, a magnet external to the chamber and rotatably coupled with the motor, and an outflow member configured to direct airflow to a user. The magnetically-responsive object may be coated with micronized dry powder particles, and the motor may be operable to rotate the magnet about an axis. Rotation of the magnet creates a magnetic field that causes the magnetically-responsive object to move in response to the magnetic field and collide with a side wall of the container to deaggregate the dry powder particles and aerosolize the dry powder in the chamber.

First claim

1 . A drug powder delivery device comprising:
a container defining a chamber, the chamber containing a magnetically-responsive object and a dose of micronized drug powder particles; an outflow member configured to direct an airflow from the chamber; a motor; and a magnet coupled with the motor, the motor being operable to move the magnet, wherein magnetic attraction between the magnet and the magnetically-responsive object causes a responsive movement of the magnetically-responsive object in response to movement of the magnet by the motor and deaggregates at least a portion of the dose of the micronized drug powder particles into the airflow.

2 . The drug powder delivery device of claim 1 , wherein the magnetically-responsive object comprises a second magnet.

3 . The drug powder delivery device of claim 1 , wherein the magnetically-responsive object is coated with a polymer.

4 . (canceled)

5 . (canceled)

6 . The drug powder delivery device of claim 3 , wherein the polymer is Teflon.

7 . The drug powder delivery device of claim 1 , wherein the outflow member includes a mouthpiece in fluid communication with the chamber.

8 . The drug powder delivery device of claim 1 , further comprising at least one air inlet arranged to direct air into the chamber.

9 . The drug powder delivery device of claim 8 , wherein the at least one air inlet comprises one or more hollow shafts extending tangentially from a side wall of the container.

10 . The drug powder delivery device of claim 1 , wherein the container includes a wall having an uneven inner surface.

11 . The drug powder delivery device of claim 1 , wherein the dry powder drug particles comprise at least one of an antibiotic, a long-acting beta agonist, a steroid, and an immunosuppressive.

12 . A method comprising:
providing or receiving a magnet and a container defining a chamber containing a magnetically-responsive object and a dose of micronized drug powder particles, wherein the magnetically-responsive object is magnetically attracted to the magnet; moving the magnet, wherein the magnetic attraction between the magnet and the magnetically-responsive object causes a responsive movement of the magnetically-responsive object that deaggregates at least a portion of the micronized drug powder particles into the chamber; and directing the airflow including the deaggregated micronized drug powder particles from the chamber through an outflow member.

13 . (canceled)

14 . (canceled)

15 . The method of claim 12 , wherein the moving of the magnet begins in response to activation by a user.

16 . The method of claim 15 , wherein the activation comprises inhalation by a user at a mouthpiece fluidly coupled with the outflow member.

17 . (canceled)

18 . The drug powder delivery device of claim 1 , wherein the responsive movement of the magnetically-responsive object deaggregates and at least partially aerosolizes the micronized drug powder particles.

19 . The drug powder delivery device of claim 1 , wherein the dose of the micronized drug powder particles in the chamber comprises a pre-measured amount of the micronized drug powder particles.

20 . The drug powder delivery device of claim 1 , wherein the motor is operable to rotate the magnet and wherein the responsive movement comprises a rotation of the magnetically-responsive object that deaggregates at least the portion of the dose of the micronized drug powder particles.

21 . The method of claim 12 , wherein the magnetically-responsive object comprises a second magnet.

22 . The method of claim 12 , wherein the moving of the magnet is such that the responsive movement of the magnetically-responsive object deaggregates and at least partially aerosolizes the micronized drug powder particles.

23 . The method of claim 12 , wherein the moving of the magnet comprises rotating the magnet and wherein the responsive movement comprises a corresponding rotation of the magnetically-responsive object that deaggregates the micronized drug powder particles.

24 . The method of claim 12 , wherein the magnet is coupled to a motor, and wherein the moving of the magnet comprises running the motor to move the magnet.

25 . The method of claim 12 , wherein the dose of the micronized drug powder particles in the chamber comprises a pre-measured amount of the micronized drug powder particles.

Assignees

• Stc Unm

Inventors

• Maynard Nicola Jeanne
• Smyth Hugh D C

Classifications

• A61M15/0035

  Piercing means · CPC title

• A61M15/0006

  using rotating means · CPC title

• A61M2016/0015

  inhalation detectors · CPC title

• A61M15/0021

  Mouthpieces therefor · CPC title

• A61M15/0086 Primary

  Inhalation chambers · CPC title