Method For Treating A Biological Fluid

Patent metadata

Field	Value
Publication number	US-2017340802-A1
Application number	US-201715490594-A
Country	US
Kind code	A1
Filing date	Apr 18, 2017
Priority date	May 26, 2016
Publication date	Nov 30, 2017
Grant date	—

Abstract

A method for detoxifying a patient's blood by removing bilirubin from the patient's blood includes obtaining a batch of blood from the patient; controlling a pH of the blood so as to maintain the pH at approximately pH 7.4; controlling a temperature of the blood so as to maintain the temperature at approximately 37° C.; providing date pit-derived activated carbon; soaking the date pit-derived activated carbon within the blood for approximately 10-16 hours; and returning the detoxified blood to the patient.

First claim

1 . A method for treating a biological fluid obtained from a patient, for detoxifying the biological fluid, the method comprising:
providing date pit-derived activated carbon; and contacting the biological fluid with the date pit-derived activated carbon.

2 . The method for treating as claimed in claim 1 , wherein the method for treating is a method for detoxifying the biological fluid by removing protein bound impurities from the biological fluid.

3 . The method for treating as claimed in claim 2 , wherein the contacting of the biological fluid with the date pit-derived activated carbon results in sorption of the protein bound impurities present in the biological fluid, by the date pit-derived activated carbon.

4 . The method for treating as claimed in claim 1 , wherein the contacting of the biological fluid with the date pit-derived activated carbon comprises soaking the date pit-derived activated carbon within the biological fluid.

5 . The method for treating as claimed in claim 4 , wherein the date pit-derived activated carbon is soaked within the biological fluid for a period of time of approximately 10-16 hours.

6 . The method for treating as claimed in claim 1 , wherein the method includes grinding the date pit-derived activated carbon so as to obtain granules of the date pit-derived activated carbon.

7 . The method for treating as claimed in claim 1 , wherein the method further includes controlling a pH of the biological fluid so as to maintain the pH at approximately pH 6.9-7.9, preferably pH 7.4.

8 . The method for treating as claimed in claim 1 , wherein the method further includes controlling a temperature of the biological fluid so as to maintain the temperature at approximately 36.9-37.9° C. preferably approximately 37° C.

9 . The method for treating as claimed in claim 1 , wherein the method includes obtaining the biological fluid from the patient.

10 . The method for treating as claimed in claim 1 , wherein the method includes treating batches of the biological fluid, whereby a volume of the biological fluid is obtained from the patient and thereafter, the treated biological fluid is returned to the patient.

11 . The method for treating as claimed in claim 1 , wherein the biological fluid is in the form of blood and wherein the method is for the removal of protein bound impurities from the patient's blood.

12 . The method for treating as claimed in claim 11 , wherein the protein bound impurities removed from the blood are in the form of albumin bound toxins.

13 . The method for treating as claimed in claim 11 , wherein the protein bound impurities removed from the blood are in the form of bilirubin.

14 . The method for treating as claimed in claim 1 , wherein providing date pit-derived activated carbon includes providing date pits and physically and chemically activating the date pits so as to obtain said date pit-derived activated carbon.

15 . The method for treating as claimed in claim 14 , wherein the physical activation includes carbonizing the date pits in an inert atmosphere.

16 . The method for treating as claimed in claim 15 wherein the physical activation further includes exposing the carbonized date pits at an elevated temperature to at least one of oxidizing gasses and steam.

17 . The method for treating as claimed in claim 15 wherein the chemical activation includes exposing the carbonized date pits to dehydrating chemicals.

Assignees

• Univ United Arab Emirates

Inventors

• Alnaqbi Ali Hilal
• Mourad Abdel Hamid
• Alshehhi Azza Abdulla
• Almarzooqi Mariam Sultan
• Aljaberi Rania Yaslam
• Almuhairi Sherina Matar

Classifications

• C12N5/067

  Hepatocytes · CPC title

• A61M1/3679 Primary

  by absorption (A61M1/3675 takes precedence) · CPC title

• B01J20/20

  comprising free carbon; comprising carbon obtained by carbonising processes · CPC title

• A61M2202/07

  Proteins · CPC title

• A61K35/14

  Blood; Artificial blood (perfluorocarbons A61K31/02; umbilical cord blood A61K35/51; haemoglobin A61K38/42) · CPC title