An external composition for skin

Patent metadata

Field	Value
Publication number	US-2017304167-A1
Application number	US-201515520738-A
Country	US
Kind code	A1
Filing date	Oct 20, 2015
Priority date	Oct 21, 2014
Publication date	Oct 26, 2017
Grant date	—

Abstract

An object of the present invention is to provide an external composition for skin excellent in ultraviolet-ray absorbability. The present invention relates to the external composition for skin comprising (a) an ultraviolet-ray absorber, and (b) an inorganic phosphor. (a) The ultraviolet-ray absorber preferably contains at least one ultraviolet-ray absorber which absorbs UVB. Also, (a) the ultraviolet-ray absorber is more preferably at least one ultraviolet-ray absorber selected from the group consisting of 2-ethylhexyl paramethoxycinnamate, phenylbenzimidazole sulfonic acid, etc.

First claim

1 . An external composition for skin which comprises
(a) an ultraviolet-ray absorber and (b) an inorganic phosphor.

2 . The external composition for skin according to claim 1 , wherein (a) the ultraviolet-ray absorber contains at least one kind of an ultraviolet-ray absorber which absorbs UVB.

3 . The external composition for skin according to claim 1 , wherein (a) the ultraviolet-ray absorber is at least one kind of an ultraviolet-ray absorber selected from the group consisting of 2-ethylhexyl paramethoxycinnamate, phenylbenzimidazole sulfonic acid, isopropyl methoxycinnamate, octyl methoxycinnamate, para-amino-benzoic acid, ethyl PABA, ethyl-dihydroxypropyl PABA, ethylhexyl-dimethyl PABA, homosalate, ethylhexyl salicylate, 3-benzylidene camphor, 4-methylbenzylidene camphor, benzylidene camphor sulfonic acid, camphor benzalkonium methosulfate, polyacrylamidomethyl benzylidene camphor, diethylhexyl butamidotriazone, octyl triazone, disodium phenyl dibenzimidazole tetrasulfonate, a polyorganosiloxane having a benzalmalonate functional group, 4-tert-butyl-4-methoxybenzoylmethane, hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate, 2-(2′-hydroxy-5 ‘ -methyl-phenyl)benzotriazole, 2-[4,6-bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl] -5-[(octyl)oxy]-phenol, 2-ethylhexyl dimethoxybenzylideneoxoimidazolidine propionate, 6-(4-methoxyphenyl)-1,3,5-triazine, tetrahydroxybenzophenone, 2-hydroxy-4-methoxy-benzophenone, 2,4-bis-[{4-(2-ethylhexyloxy)-2-hydroxy} -phenyl]-drometrizole trisiloxane, 2,2’-methylenebis [6-(2H-benzotriazole-2-yl)-4-(1,1,3,3-tetramethyl-butyl)phenol] and octocrylene.

4 . The external composition for skin according to claim 1 , wherein (b) the inorganic phosphor is aluminate phosphor and/or titanate phosphor.

5 . The external composition for skin according to claim 4 , wherein the inorganic phosphor is an alkaline earth metal aluminate phosphor and/or an alkaline earth metal titanate phosphor.

6 . The external composition for skin according to claim 5 , wherein the alkaline earth metal aluminate phosphor is calcium manganese aluminate.

7 . The external composition for skin according to claim 6 , wherein the calcium manganese aluminate is represented by the following formula (1);
Ca X Al y O (2X+3Y+4Z)/2 :Mn 4+ Z   (1)
wherein 0.1<X<1.05, 11.9<Y≦12 and 0.0005<Z<0.1.

8 . The external composition for skin according any one of claims 1 to 3 , wherein (a) the ultraviolet-ray absorber contains 2-ethylhexyl paramethoxycinnamate.

9 . The external composition for skin according to any one of claims 1 to 3 , wherein (a) the ultraviolet-ray absorber contains 2-ethylhexyl paramethoxycinnamate and hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate.

10 . The external composition for skin according to any one of claims 1 to 3 , wherein a content of (b) the inorganic phosphor is 0.1 to 10% by mass based on the whole external composition for skin.

11 . The external composition for skin according to any one of claims 1 to 3 , wherein it is a sunscreen composition.

12 . The external composition for skin according to claim 4 , wherein (a) the ultraviolet-ray absorber contains 2-ethylhexyl paramethoxycinnamate.

13 . The external composition for skin according to claim 4 , wherein (a) the ultraviolet-ray absorber contains 2-ethylhexyl paramethoxycinnamate and hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate.

14 . The external composition for skin according to claim 4 , wherein a content of (b) the inorganic phosphor is 0.1 to 10% by mass based on the whole external composition for skin.

15 . The external composition for skin according to claim 4 , wherein it is a sunscreen composition.

16 . The external composition for skin according to claim 5 , wherein (a) the ultraviolet-ray absorber contains 2-ethylhexyl paramethoxycinnamate.

17 . The external composition for skin according to claim 5 , wherein (a) the ultraviolet-ray absorber contains 2-ethylhexyl paramethoxycinnamate and hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate.

18 . The external composition for skin according to claim 5 , wherein a content of (b) the inorganic phosphor is 0.1 to 10% by mass based on the whole external composition for skin.

19 . The external composition for skin according to claim 5 , wherein it is a sunscreen composition.

Assignees

• Rohto Pharma

Inventors

• Tate Yumiko
• Kimura Shun

Classifications

• A61K8/26 Primary

  Aluminium; Compounds thereof · CPC title

• A61Q19/00

  Preparations for care of the skin · CPC title

• A61K2800/40

  Chemical, physico-chemical or functional or structural properties of particular ingredients · CPC title

• A61K8/347 Primary

  Phenols · CPC title

• A61K8/24

  Phosphorous; Compounds thereof · CPC title