Multi-Component Voxel Separation Using Magnetic Resonance Fingerprinting With Compartment Exchange
US-2016282434-A1 · Sep 29, 2016 · US
US2017276751A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2017276751-A1 |
| Application number | US-201515512085-A |
| Country | US |
| Kind code | A1 |
| Filing date | Aug 17, 2015 |
| Priority date | Sep 18, 2014 |
| Publication date | Sep 28, 2017 |
| Grant date | — |
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The present invention relates to a method for side-band suppression in a Magnetic Resonance imaging, MRI, system ( 100 ), the method comprising providing a first multiband RF pulse for simultaneously exciting at least two slices in a subject ( 118 ) at a first and a second frequency band ( 301,303 ) and to acquire using the MRI system ( 100 ) signals ( 307, 308 ) from the excited two slices and at least one additional signal ( 309 ) at a third frequency band ( 305 ), the additional signal ( 309 ) resulting from a sideband excitation of a slice different from the two slices; using the first multiband RF pulse for determining the additional signal ( 309 ); deriving a pre-compensating term from the first multiband RF pulse and the additional signal ( 309 ), adding the pre-compensating term to the first multiband RF pulse to obtain a second multiband RF pulse, thereby replacing the first multiband RF pulse by the second multiband RF pulse for suppressing at least part of the additional signal ( 309 ).
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1 . A method for side-band suppression in a Magnetic Resonance imaging, MRI, system, the method comprising: a) providing a first multiband RF pulse for simultaneously exciting at least two slices in a subject at a first and a second frequency band and using the MRI system acquire MR signals from the excited two slices and at least one additional MR signal at a third frequency band, the additional MR signal resulting from a sideband excitation due to the first multiband RF pulse of a slice different from the two slices; and b) deriving a pre-compensating term from the first multiband RF pulse and the additional signal, adding the pre-compensating term to the first multiband RF pulse to obtain a second multiband RF pulse, thereby replacing the first multiband RF pulse by the second multiband RF pulse for suppressing at least part of the additional signal upon exciting at least two slices in a subject by the second multiband RF pulse. 2 . The method of claim 1 , further comprising: repeating the determining of the additional signal and the deriving step c) using the second multiband RF pulse as the first multiband RF pulse in step b) until the supressed at least part of the additional signal is higher than a predetermined minimum side-band signal amplitude. 3 . The method of claim 1 , further comprising: exciting the at least two slices using the second multiband RF pulse for reconstructing signals from RF coils of the MRI system, wherein reconstructing a signal from an RF coil of the RF coils is performed in accordance with formula S q *(f * x) q,1 where: q refers to a slice of the two slices and the additional slice, S q is a sensitivity of the RF coil for q, f is the normalized measured signal amplitudes of all lobes (main lobes and side lobes representing the main and additional signal components) at q and x is the signal from q. 4 . The method of claim 1 , wherein determining the additional signal comprises: exciting the two slices using the first multiband RF pulse; reconstructing an image using acquired MR data for the two slices in response to the first multiband RF pulse; and identifying using the reconstructed image the additional signal. 5 . The method of claim 1 , wherein the MRI system comprises an RF amplifier for amplifying RF pulses generated at the MRI system, wherein determining the additional signal comprises: exciting the two slices using the first multiband RF pulse; receiving the first multiband RF pulse as the output of the RF amplifier or the output of an RF coil of the MRI system; applying a Fourier transformation or a Block simulation to the received first multiband RF pulse for obtaining a frequency spectrum of the received first multiband RF pulse; and identifying the additional signal in the frequency spectrum. 6 . The method of claim 1 , wherein determining the additional signal comprises receiving from a user of the MRI system data indicative of the additional signal being a sideband signal at the third frequency band. 7 . The method of claim 1 , wherein determining the additional signal comprises: providing history data indicative of one or more multiband RF pulses and associated frequency spectrums; identifying a multiband RF pulse of the one or more multiband RF pulses that corresponds to the first multiband RF pulse; identifying the additional signal ( 309 ) using the frequency spectrum associated with the identified multiband RF pulse. 8 . The method of claim 4 , wherein identifying comprises: determining the geometry of the subject; using the determined geometry for determining a circumference area around the first and second frequency bands in the frequency spectrum; and identifying the additional signal within the circumference area. 9 . The method of claim 1 , wherein the first multiband RF pulse is defined as Ae i(φ+2πft) +Ae i(φ−2πft) =Ae iφ ·2·cos(2πf·t), wherein the second multiband RF pulse is defined as Ae iφ ·(2·cos(2πf·t)−h(f,t)) where Ae iφ · h ( f,t )= Ae iφ ·Σ k=1 N s k cos(( k )·2πf·t+φ k ) is the pre-compensating term, s k being a tuning parameter representing the ratio between the amplitude of one of the signals at the first or second frequency band and the amplitude of the additional signal at the third frequency band, ( 2 k)f comprising the third frequency band, φ k being the phase difference between the additional signal and one of the signals from the two slices, N determining the number of the at least one additional signal. 10 . The method of claim 1 , the second multiband RF pulse is defined as Ae iφ ·g(f,t)·m(f,t) where m(f,t) is a harmonic function and g(f,t)=2·cos(2πf·t), wherein the Fourier transform of g(f,t)m(f,t) over t gives response close to 1 at f and −f, and close to 0 elsewhere. 11 . A computer program product comprising computer executable instructions to perform the method steps of the method of claim 1 . 12 . A RF pulse generator for a magnetic resonance imaging, MRI, system for side-band suppression, wherein a first multiband RF pulse is provided for simultaneously exciting at least two slices in a subject at a first and a second frequency band and to acquire using the MRI system MR signals from the excited two slices and at least one additional MR signal at a third frequency band, the additional MR signal resulting from a sideband excitation of a slice different from the two slices, the RF pulse generator being configured for using the first multiband RF pulse for determining the additional MR signal; deriving a pre-compensating term from the first multiband RF pulse and the additional signal, adding the pre-compensating term to the first multiband RF pulse to obtain a second multiband RF pulse, thereby replacing the first multiband RF pulse by the second multiband RF pulse for suppressing at least part of the additional MR signal upon exciting at least two slices in a subject by the second multiband RF pulse. 13 . A magnetic resonance imaging, MRI, system for acquiring magnetic resonance data comprising an RF pulse generator according to claim 12 .
Correction of image distortions, e.g. due to magnetic field inhomogeneities · CPC title
Signal processing systems, e.g. using pulse sequences {; Generation or control of pulse sequences; Operator console} · CPC title
Control of the operation of the MR system, e.g. setting of acquisition parameters prior to or during MR data acquisition, dynamic shimming, use of one or more scout images for scan plane prescription (G01R33/546 takes precedence) · CPC title
with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy · CPC title
of multiple slices · CPC title
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